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The map label for this gene is yegE [H]

Identifier: 54293173

GI number: 54293173

Start: 247036

End: 247914

Strand: Reverse

Name: yegE [H]

Synonym: lpl0219

Alternate gene names: 54293173

Gene position: 247914-247036 (Counterclockwise)

Preceding gene: 54293174

Following gene: 54293164

Centisome position: 7.41

GC content: 34.02

Gene sequence:

>879_bases
ATGCTTACAAACATTGAAAGAGCAAAACTTCAATTAATTGATGAAACCAGCGATATGGTCATTATAACCAAAGCGGAACC
ACTTGATGCACCTAATGGTCCGGAAGTGGTTTGGGTGAATAAAGCCTTTGAAAAAATTTCAAAATATAAAGCCAATGAAA
TTATTGGCCAAACACCACGCATCCTTCAAGGTAAGGAAACCGATCAAAACACATTAAAAATGATAAAAGAAGCAATCAAA
GCTCAAATGAATATCAATGTGGATTTATTAAATTATACTAAGGATGGAACACCTTATTGGATTAATTTTTCAATAGTATA
TTTGAGAGACGGACAGGGTAATTTATGTTATTTAGGCGCAATAGAAAAAGACATCTCCGCAATCAAGAATTTAAATATTC
AATTATCTGAAAAAGCAAAGACTGATCCACTTACCAATGTTTACAATCAGGAAAATTTCTTCATTGCAGGGAATGAAGCG
GTTAAAAACTTTCATCAGAACCAGGAAACAGTTGGATTATTATTTTTCGATATTGATGATTTTAAAGGAATAAACGATAC
GCAAGGGCATATTTATGGTGATAAGATATTAAAAAAAGTTGCCCAGGAATCTTTAAAGCTTGTTCGTAAAACGGATAATG
TATTTCGATATGGCGGCGATGAGTTTGCTATTATTTTTTCAGGCATTGACGTGAAAATCCTGGAAAGAAAAGCACAACAG
CTACAAAAAAAGCTGGCAAAATCTCACATCTCTGTGAGCATTGGAGGGACCATTTCAAAGCAAAGTGACAAATCGATAAG
CACCCTCTTGGCAAGAGCGGATGAAGCACTCTATTACGTCAAAGCCAATAAAAAAGGATTATTTTTTATCAGAAAATAA

Upstream 100 bases:

>100_bases
ATCAAGGTTTTTTGTTTGAGAAACCTATGCCTTACGAAAAAATACCCGACTATATCAAAACAAGCACACAAAAATGAATT
GGCTATTGGATATATGACAA

Downstream 100 bases:

>100_bases
TCACATTTTGATGCTGCCAAATTGCGAGGAAATTAAAACCAGTGACGCTCAATCCAATGACATCTACTTTTAAACAATTC
CTTTATGCCATATTTTCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLTNIERAKLQLIDETSDMVIITKAEPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETDQNTLKMIKEAIK
AQMNINVDLLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIEKDISAIKNLNIQLSEKAKTDPLTNVYNQENFFIAGNEA
VKNFHQNQETVGLLFFDIDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSISTLLARADEALYYVKANKKGLFFIRK

Sequences:

>Translated_292_residues
MLTNIERAKLQLIDETSDMVIITKAEPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETDQNTLKMIKEAIK
AQMNINVDLLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIEKDISAIKNLNIQLSEKAKTDPLTNVYNQENFFIAGNEA
VKNFHQNQETVGLLFFDIDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSISTLLARADEALYYVKANKKGLFFIRK
>Mature_292_residues
MLTNIERAKLQLIDETSDMVIITKAEPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETDQNTLKMIKEAIK
AQMNINVDLLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIEKDISAIKNLNIQLSEKAKTDPLTNVYNQENFFIAGNEA
VKNFHQNQETVGLLFFDIDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSISTLLARADEALYYVKANKKGLFFIRK

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=264, Percent_Identity=24.6212121212121, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=32.7380952380952, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787541, Length=261, Percent_Identity=23.7547892720307, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=180, Percent_Identity=31.6666666666667, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=30, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=29.1925465838509, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788956, Length=116, Percent_Identity=35.3448275862069, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787816, Length=114, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=30.1675977653631, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=31.1688311688312, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787056, Length=117, Percent_Identity=37.6068376068376, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=28.3950617283951, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 32986; Mature: 32986

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNIERAKLQLIDETSDMVIITKAEPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPR
CCCCCCHHHEEEEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
ILQGKETDQNTLKMIKEAIKAQMNINVDLLNYTKDGTPYWINFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEECCCCCEEEEEC
IEKDISAIKNLNIQLSEKAKTDPLTNVYNQENFFIAGNEAVKNFHQNQETVGLLFFDIDD
HHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECCHHHHHHHCCCCEEEEEEEEECC
FKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISKQSDKSISTLLARADEALYYVKANKKGLFFIRK
HHHHHHHHHEEEEECCEECCCCCHHHHHHHHHHCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MLTNIERAKLQLIDETSDMVIITKAEPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPR
CCCCCCHHHEEEEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
ILQGKETDQNTLKMIKEAIKAQMNINVDLLNYTKDGTPYWINFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEECCCCCEEEEEC
IEKDISAIKNLNIQLSEKAKTDPLTNVYNQENFFIAGNEAVKNFHQNQETVGLLFFDIDD
HHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECCHHHHHHHCCCCEEEEEEEEECC
FKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISKQSDKSISTLLARADEALYYVKANKKGLFFIRK
HHHHHHHHHEEEEECCEECCCCCHHHHHHHHHHCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]