| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is dnaN [H]
Identifier: 54292966
GI number: 54292966
Start: 1576
End: 2679
Strand: Direct
Name: dnaN [H]
Synonym: lpl0002
Alternate gene names: 54292966
Gene position: 1576-2679 (Clockwise)
Preceding gene: 54292965
Following gene: 54292967
Centisome position: 0.05
GC content: 34.51
Gene sequence:
>1104_bases TTGTTTGAGCTAACCATTAAAAAAGAAGATCTGCTTACCCCATTGCTTACTGTTTCCGGAGCCGTAGATAAGAAGCAGTC TTTGGCTATTTTGTCCCATTTTTTATTAAAACTGTCCGATGGACTTTTATATATTACGGCTACAGATTTGGAAATTGAAA TGTCCGCACAAGTGGCATGTGATTCCAAGAATACTAGTGGTTCTATTACAGTACCAGCCAAGAAATTCATTGATATTATC AGGTCATTAGATGAAAACGCTTCGCCATCTATCGTTTTTGATAAAGCTTTAGTGACGATAAAACAAAACCGAAGTACATT TAAACTGGCAACTTTGCCTGCTGAGAATTATCCCAGTAGTGAAGATGAATGCAATGATGTCGAGTTGACTATCCCGCGTT TGGTTTTGTTGCAGTTATTGCAATCTACTCATTTTGCTATGTCTCAGCAGGATGTTCGTATATTTTTAAATGGATTATTG CTGGAGTTTGACAGTAATATTATTTCAGCGGTTGCTACTGATGGACACAGAATGGCTATATCGCGATATTCCTGTAATAA TATTACTCAAAAAAAATTACTTATACCCAAAAAAGGGGTGCAAGAATTATTAAGATTATTGAATTGTATTAATGACGAAC AAGTTTTGTTGACAGCGGGAAAATCTCATATTAAGTTGATTACCAATCAATTTGTATTTTTGTCAAAATTAATCGAAGCA CGCTTTCCACCTTACACTAAAGCTATACCAAGAGAACAGGATAAATGTATTGTTATTGATTGCGCTTCGCTCAAGCGTGC ATTATCTCGTATTGTCATTTTAGCTCATGAAAAGTCAAAGGCTGTCTTGTTGCATTTACAACAAGGTCAGTTAACTTTAA TTGCCAATAATAATGAGCAAGAAGAGGCAATTGAAACATTAAGTGCTGAAACACAAGGTGATGAACTCAAAATCGGACTT AATGCAACCTATTTGCTGGATGTTTTAACTCACTTTTCTGAAGGTCAAATCAGGTTATCAATGTCTAATACGGAAAGCAG TATTTTAATTGAGTCATTAATCAATGATAATTATCAATACATTATTATGCCTATGAAAATATGA
Upstream 100 bases:
>100_bases GCTTGTCGGAAGGTTAAAGAATTAATCCAGGATGATAGCGATTTTGCTGAAGATTATAAAAATTTAATGCGAATATTATC TTCTTGATACGGAGTCTATC
Downstream 100 bases:
>100_bases TTTTATCTGAAGTTAGAATTCATAATTTTCGGAATATCGCTTCGACTAGTTTAATCCTAAATCCCAATTTTAATTGTATT ACAGGACCTAATGGCAGTGG
Product: DNA polymerase III, beta chain
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 367; Mature: 367
Protein sequence:
>367_residues MFELTIKKEDLLTPLLTVSGAVDKKQSLAILSHFLLKLSDGLLYITATDLEIEMSAQVACDSKNTSGSITVPAKKFIDII RSLDENASPSIVFDKALVTIKQNRSTFKLATLPAENYPSSEDECNDVELTIPRLVLLQLLQSTHFAMSQQDVRIFLNGLL LEFDSNIISAVATDGHRMAISRYSCNNITQKKLLIPKKGVQELLRLLNCINDEQVLLTAGKSHIKLITNQFVFLSKLIEA RFPPYTKAIPREQDKCIVIDCASLKRALSRIVILAHEKSKAVLLHLQQGQLTLIANNNEQEEAIETLSAETQGDELKIGL NATYLLDVLTHFSEGQIRLSMSNTESSILIESLINDNYQYIIMPMKI
Sequences:
>Translated_367_residues MFELTIKKEDLLTPLLTVSGAVDKKQSLAILSHFLLKLSDGLLYITATDLEIEMSAQVACDSKNTSGSITVPAKKFIDII RSLDENASPSIVFDKALVTIKQNRSTFKLATLPAENYPSSEDECNDVELTIPRLVLLQLLQSTHFAMSQQDVRIFLNGLL LEFDSNIISAVATDGHRMAISRYSCNNITQKKLLIPKKGVQELLRLLNCINDEQVLLTAGKSHIKLITNQFVFLSKLIEA RFPPYTKAIPREQDKCIVIDCASLKRALSRIVILAHEKSKAVLLHLQQGQLTLIANNNEQEEAIETLSAETQGDELKIGL NATYLLDVLTHFSEGQIRLSMSNTESSILIESLINDNYQYIIMPMKI >Mature_367_residues MFELTIKKEDLLTPLLTVSGAVDKKQSLAILSHFLLKLSDGLLYITATDLEIEMSAQVACDSKNTSGSITVPAKKFIDII RSLDENASPSIVFDKALVTIKQNRSTFKLATLPAENYPSSEDECNDVELTIPRLVLLQLLQSTHFAMSQQDVRIFLNGLL LEFDSNIISAVATDGHRMAISRYSCNNITQKKLLIPKKGVQELLRLLNCINDEQVLLTAGKSHIKLITNQFVFLSKLIEA RFPPYTKAIPREQDKCIVIDCASLKRALSRIVILAHEKSKAVLLHLQQGQLTLIANNNEQEEAIETLSAETQGDELKIGL NATYLLDVLTHFSEGQIRLSMSNTESSILIESLINDNYQYIIMPMKI
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped
COG id: COG0592
COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1790136, Length=367, Percent_Identity=38.1471389645777, Blast_Score=288, Evalue=3e-79,
Paralogues:
None
Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001001 - InterPro: IPR022635 - InterPro: IPR022637 - InterPro: IPR022634 [H]
Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 40958; Mature: 40958
Theoretical pI: Translated: 5.94; Mature: 5.94
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFELTIKKEDLLTPLLTVSGAVDKKQSLAILSHFLLKLSDGLLYITATDLEIEMSAQVAC CEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECEEEEEEEEEEE DSKNTSGSITVPAKKFIDIIRSLDENASPSIVFDKALVTIKQNRSTFKLATLPAENYPSS CCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCC EDECNDVELTIPRLVLLQLLQSTHFAMSQQDVRIFLNGLLLEFDSNIISAVATDGHRMAI CCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCHHHHHHCCCCCEEEE SRYSCNNITQKKLLIPKKGVQELLRLLNCINDEQVLLTAGKSHIKLITNQFVFLSKLIEA EEECCCCCCHHEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHHH RFPPYTKAIPREQDKCIVIDCASLKRALSRIVILAHEKSKAVLLHLQQGQLTLIANNNEQ CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHEEEEEECCCCEEEEEEECCCEEEEECCCCH EEAIETLSAETQGDELKIGLNATYLLDVLTHFSEGQIRLSMSNTESSILIESLINDNYQY HHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEE IIMPMKI EEEEECC >Mature Secondary Structure MFELTIKKEDLLTPLLTVSGAVDKKQSLAILSHFLLKLSDGLLYITATDLEIEMSAQVAC CEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECEEEEEEEEEEE DSKNTSGSITVPAKKFIDIIRSLDENASPSIVFDKALVTIKQNRSTFKLATLPAENYPSS CCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCC EDECNDVELTIPRLVLLQLLQSTHFAMSQQDVRIFLNGLLLEFDSNIISAVATDGHRMAI CCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCHHHHHHCCCCCEEEE SRYSCNNITQKKLLIPKKGVQELLRLLNCINDEQVLLTAGKSHIKLITNQFVFLSKLIEA EEECCCCCCHHEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHHH RFPPYTKAIPREQDKCIVIDCASLKRALSRIVILAHEKSKAVLLHLQQGQLTLIANNNEQ CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHEEEEEECCCCEEEEEEECCCEEEEECCCCH EEAIETLSAETQGDELKIGLNATYLLDVLTHFSEGQIRLSMSNTESSILIESLINDNYQY HHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEE IIMPMKI EEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]