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The map label for this gene is ruvC

Identifier: 54297205

GI number: 54297205

Start: 1387627

End: 1388151

Strand: Direct

Name: ruvC

Synonym: lpp1250

Alternate gene names: 54297205

Gene position: 1387627-1388151 (Clockwise)

Preceding gene: 54297204

Following gene: 54297206

Centisome position: 39.61

GC content: 40.95

Gene sequence:

>525_bases
ATGACGATTATATTAGGGATAGATCCAGGCTCACGGGTTACAGGATATGGATTGATTAAAGAATCTGACCGTAAAATCGC
GTACATCGATAGCGGTTGTATTCGCACATCAAACGATGTGGAATTAAGTCATAAATTATTGCAAATATATGATGGAATAT
GTGAGCTAATGGATCACTATTCCCCAACTGAGGTTGCTATTGAGCAGATATTTATGCATAACAATCCTAATTCAGCTTTG
AAATTAGGACATGCGCGGGGGGTTGCCATGGTAGCAGCAGCCTCACATCGTGCGAAAATCTGTGAGTATTCAGCAAGAGA
AATAAAACAAAGTGTGGTTGGTTATGGGGCTGCCGAAAAAGATCAAGTAAGTCATATGGTTGTAGAGCTTCTTCAGCTCA
ATCGAGCTCCTCAAAAAGACGCTGCCGATGCTTTGGCAATAGCAATATGTCATAGCCATATGAGAAATGGTTTGTCAAAA
TTAATCGGTTCAAGAGGAACGAAACGCAGGAGGATGAGACTATGA

Upstream 100 bases:

>100_bases
GCTTAATTAAACTGATTGATATGCTGGAAGATTTGGATGATGTCCAAGAAGTTTACAGCAATGCTGAATTTTCTGAAAAA
ATATTAGAATCAATGAATTA

Downstream 100 bases:

>100_bases
TAGGCTGGCTCCATGGTCAAATTATAGATAAGCATCAGCCAGGAAAATTGGTTCTGGATGTCAATGGCGTAGGATATGAT
GTAGAAACATCTTTGAATAC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDVELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL

Sequences:

>Translated_174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDVELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL
>Mature_173_residues
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDVELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSALK
LGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKL
IGSRGTKRRRMRL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=174, Percent_Identity=54.0229885057471, Blast_Score=163, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_LEGPA (Q5X5S0)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123574.1
- ProteinModelPortal:   Q5X5S0
- SMR:   Q5X5S0
- STRING:   Q5X5S0
- GeneID:   3116604
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1250
- LegioList:   lpp1250
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- BioCyc:   LPNE297246:LPP1250-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 19169; Mature: 19038

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDVELSHKLLQIYDGICELMDHY
CEEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDVELSHKLLQIYDGICELMDHY
EEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA