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The map label for this gene is lspA [H]

Identifier: 54296959

GI number: 54296959

Start: 1108315

End: 1108779

Strand: Direct

Name: lspA [H]

Synonym: lpp1000

Alternate gene names: 54296959

Gene position: 1108315-1108779 (Clockwise)

Preceding gene: 54296958

Following gene: 54296963

Centisome position: 31.63

GC content: 37.85

Gene sequence:

>465_bases
ATGAAAAAATGGCCTTGGCTTGTACTTAGTTTTTTAGTAATTATCTGCGATCAGTTAAGTAAGTATTGGGTTGGAGTGTT
ATTAACTCCATATAAACCCATGCCAGTTATGCCTATGTTGAATTTCACTTTAGCTTTTAACACAGGCGCTGCTTTTAGTT
TTTTAAGCGGTGCAGGTGATTGGCATAGGTGGTTTTTTGCAGGCTTTAGTTTTTTAATGAGTATTATTTTGCTGATTTGG
TTAGTGCGGACACCAGAACAGGCACGATTTCAATCTGTTGGGATAAGTCTTATTCTAGGAGGCGCTATAGGCAACTTGAT
TGACAGAGGTATTCATGGTTATGTGATTGATTTTATTGACGTTTATTATAAACACCACCATTTTGCCACGTTCAACGTGG
CCGATAGCGCTATATGTATAGGAGCCGCAATTTTAGTTCTGGATTTATTGATTCGTAGGGAATAG

Upstream 100 bases:

>100_bases
GGCATAGACGGGAAGATGTTGGTCAAAATCAAGAGCATCCTGAACTGTGCTTGCGTTGTGTAGGAAATATCAGCGGATAT
CATGAAGAGAGGCTTTACAT

Downstream 100 bases:

>100_bases
ACTCAAACTGCCTAGGAAATAATGTCATAAGTTAGTGTCCTCATGTTTGACTATCCTATAACAGTAGGGTTTGTGTTCTG
GTTAGATGCAAATAATCCTG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKKWPWLVLSFLVIICDQLSKYWVGVLLTPYKPMPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIW
LVRTPEQARFQSVGISLILGGAIGNLIDRGIHGYVIDFIDVYYKHHHFATFNVADSAICIGAAILVLDLLIRRE

Sequences:

>Translated_154_residues
MKKWPWLVLSFLVIICDQLSKYWVGVLLTPYKPMPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIW
LVRTPEQARFQSVGISLILGGAIGNLIDRGIHGYVIDFIDVYYKHHHFATFNVADSAICIGAAILVLDLLIRRE
>Mature_154_residues
MKKWPWLVLSFLVIICDQLSKYWVGVLLTPYKPMPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIW
LVRTPEQARFQSVGISLILGGAIGNLIDRGIHGYVIDFIDVYYKHHHFATFNVADSAICIGAAILVLDLLIRRE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=146, Percent_Identity=46.5753424657534, Blast_Score=133, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17469; Mature: 17469

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWPWLVLSFLVIICDQLSKYWVGVLLTPYKPMPVMPMLNFTLAFNTGAAFSFLSGAGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEECCCCHHHHHCCCCH
WHRWFFAGFSFLMSIILLIWLVRTPEQARFQSVGISLILGGAIGNLIDRGIHGYVIDFID
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHEEHHHHHHHHHCCCCHHHHHHHH
VYYKHHHFATFNVADSAICIGAAILVLDLLIRRE
HHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKWPWLVLSFLVIICDQLSKYWVGVLLTPYKPMPVMPMLNFTLAFNTGAAFSFLSGAGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEECCCCHHHHHCCCCH
WHRWFFAGFSFLMSIILLIWLVRTPEQARFQSVGISLILGGAIGNLIDRGIHGYVIDFID
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHEEHHHHHHHHHCCCCHHHHHHHH
VYYKHHHFATFNVADSAICIGAAILVLDLLIRRE
HHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA