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The map label for this gene is era [H]

Identifier: 54296963

GI number: 54296963

Start: 1115589

End: 1116524

Strand: Direct

Name: era [H]

Synonym: lpp1004

Alternate gene names: 54296963

Gene position: 1115589-1116524 (Clockwise)

Preceding gene: 54296959

Following gene: 54296964

Centisome position: 31.84

GC content: 36.11

Gene sequence:

>936_bases
ATGACATGGCTGCTAGAATGTTTTAAAAATAAACAGGAATCAAGATTAATGAGTAGTTATTGTGGTTATATTGCTTTAGT
TGGCAGGCCAAACGTTGGCAAATCAACCTTATTGAATCGTATTTTACAGCAAAAATTAAGTATTACCTCAAGAAAACCAC
AAACCACGCGCCATAGTATTTTAGGAATTCGCACAGAAGGTGAATTTCAGTTTGTTTATGTAGATACTCCTGGTATTCAT
CAGGGTAATGCGAAAGCAATTAATCGCATGATGAATAAAACAGCGATTAGTGTACTACGTGACGTGGATGTGATTGCCTT
TCTAGTCGATGGAACGCATTGGAAAGACGAAGATGAGTATGTATTGAATTTAATTAAACAAGCTAAAGTTCCTTGCATCC
TGGTAGTTAACAAAGTTGACAAGATAACTGATAAAACACAACTTTTGCCTTGGATAGAGCAAATAAGTCAGCGATATCAA
TTTGCAGCCATTATTCCTTTATCGGCGAAAACTGGTTTGCAGGTGGATGAATTGGAAGGCAAATTAAAGACTTATTTGCC
AGAAGGACCACATTTGTTTCCTGATGATCAATTCACCGATCGGTCTATAAAATTTTTATGTGCCGAATTGCTCCGTGAAA
AAATTTTCCGCTTTTGTGGACAAGAATTGCCTTATTCAGTAACAGTAGATATCGAATCATTTAAGGATGAGGGAAATTTA
ATTCGTATTCATGCCTTGATTTTAGTAGACAAGGATAATCACAAGCGCATGATCATTGGTGATAAAGGCCAAAAATTAAA
AGAAATGGCAACTAATGCCCGTTTGGACATGGAAAAAATGCTAGATAAAAAGGTTTTTTTACAATGTTGGTGTAAAGTGA
AATCAGGCTGGTCAGATGATGAGCGAATACTGAAGCAATTGGGATATGACCAGTAA

Upstream 100 bases:

>100_bases
AAAATCGTTTAATTTAATGCCATTAATGCACAGGGTACTCGAATTGGAGCAGAAATAGCAAGTCTATTTTAATGAAAAAT
TTGGTATCTCTGGAAGTTTT

Downstream 100 bases:

>100_bases
ATCGCTGAATGCTTGGGTAATTCATAAGCAATGGTCTGGAGATACCAGTGCCAGACTAAAGCTTTTTACTAGGGAACTGG
GATTAATTAATTGCTTGTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIH
QGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQ
FAAIIPLSAKTGLQVDELEGKLKTYLPEGPHLFPDDQFTDRSIKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ

Sequences:

>Translated_311_residues
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIH
QGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQ
FAAIIPLSAKTGLQVDELEGKLKTYLPEGPHLFPDDQFTDRSIKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ
>Mature_310_residues
TWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIHQ
GNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQF
AAIIPLSAKTGLQVDELEGKLKTYLPEGPHLFPDDQFTDRSIKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNLI
RIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=308, Percent_Identity=26.6233766233766, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=53.7671232876712, Blast_Score=343, Evalue=8e-96,
Organism=Escherichia coli, GI87082120, Length=154, Percent_Identity=30.5194805194805, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646434, Length=300, Percent_Identity=27, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35839; Mature: 35708

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSI
CCHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHE
LGIRTEGEFQFVYVDTPGIHQGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEY
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
VLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQFAAIIPLSAKTGLQVDELEG
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHCC
KLKTYLPEGPHLFPDDQFTDRSIKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCE
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDD
EEEEEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
ERILKQLGYDQ
HHHHHHCCCCC
>Mature Secondary Structure 
TWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSI
CHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHE
LGIRTEGEFQFVYVDTPGIHQGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEY
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
VLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQFAAIIPLSAKTGLQVDELEG
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHCC
KLKTYLPEGPHLFPDDQFTDRSIKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCE
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDD
EEEEEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
ERILKQLGYDQ
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA