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The map label for this gene is murG

Identifier: 54296829

GI number: 54296829

Start: 979462

End: 980553

Strand: Direct

Name: murG

Synonym: lpp0870

Alternate gene names: 54296829

Gene position: 979462-980553 (Clockwise)

Preceding gene: 54296828

Following gene: 54296830

Centisome position: 27.96

GC content: 39.84

Gene sequence:

>1092_bases
ATGAGCCCAAGTATTGTTTTTACCGGGGGAGGAACTGCCGGACATGTAACGCCTAATATCGCTTTGATTAAGGAATTTCG
AAAAGAAGGCTGGAATGTAGAATATATCGGCTCTGTTTCCGGAATTGAAAAGGAGATGATTGAGCCGCTGGACATTCCTT
TTCATGGGGTCAGTAGCGGTAAATTGCGCAGGTATTTTAGTTTGAAGAACTTGCTTGATCCTTTCAAAATTGTTCTGGGA
ATTATTCAATCTTCTTTGCTATTTTATAAAATCAAACCCGATGTGGTTTTTTCAAAAGGTGGCTTTGTAGCCTTTCCTGT
GGTTGTAGGCGCCTGGTTAAATCGAATTCCTGTTGTCGCTCATGAGTCTGATATGAGCCCAGGACTTGCGAATCGCCTAT
CCTTTCCTTTCGTCAATAAAATATGTCTTACTTTTGATGCTGGCAAAAAATACTTTAAGCGTCAGGATAAAATAGAAGTG
ACGGGTACTCCAATTCGTCAACAGCTATTAACTGGAAATCGAATGAAAGGATTGGAGTTATGCGGATTTAATTCCTCCAA
ACCTTGCCTGCTTGTAGTGGGAGGAAGCTTAGGGGCTGGTTCAATTAACAGTTGTATTCGAAGCGCATTGAAACAATTGA
CATCAGAATTTCAAGTCATTCATCTTTGTGGCAAGGGAAAACTTGATTCTTCATTGGTTGGTGTGGAGGGATATTGCCAA
TTTGAATACGCCAATGAAGAGTTGGCTGATCTGTTCGCTGCTTCTTCTGTGGTGATTTCTCGAGCAGGAGCTAATTCTTT
GTATGAAATATTAGCATTAGGAAAACCACATATCTTAATTCCAATCTCTTCACAAGTAAGCAGAGGAGATCAAATTCAGA
ATGCAAGGTACTTCCAGGGATTGGGAATAAGCGTTGTGATTCAGGACGAGTTATTGAAAGCTGATGTTCTATTACAGGCA
GTACAGGACGTAATGCGAAAAAAAGATGAAATAGATAATAAAATCAAAGCATTAAAAATTGAGTCTGCCACTGATAAGAT
TGTGGCAATTATCAAGGAGCAAGCACATGTTCAAACCCCAAGGATTGTATGA

Upstream 100 bases:

>100_bases
TTGCAGACATTGCTCAAACCGGAGTGGATTTTATTTCAGTTGGATCCATCACCAAATCAATTCAAGCAATTGATTTGAGC
TTATTGATTAGGGAAACATT

Downstream 100 bases:

>100_bases
TTACATATGCCAACAGTGGCAAGAAGAGATATTGCCAAGTTTATGTGACTACATAAAAATCCCTAATAAATCTCCTCACT
TTGATGCAAAATGGGAAGAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
VQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Sequences:

>Translated_363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
VQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
>Mature_362_residues
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGI
IQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVT
GTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQF
EYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAV
QDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=27.3743016759777, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_LEGPA (Q5X6U5)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123198.1
- ProteinModelPortal:   Q5X6U5
- SMR:   Q5X6U5
- STRING:   Q5X6U5
- GeneID:   3119573
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0870
- LegioList:   lpp0870
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- BioCyc:   LPNE297246:LPP0870-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39653; Mature: 39522

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSG
CCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLEL
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCEEE
CGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCC
RIV
CCC
>Mature Secondary Structure 
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSG
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLEL
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCEEE
CGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCC
RIV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA