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The map label for this gene is katC [H]

Identifier: 54027513

GI number: 54027513

Start: 5868086

End: 5869747

Strand: Reverse

Name: katC [H]

Synonym: nfa55390

Alternate gene names: 54027513

Gene position: 5869747-5868086 (Counterclockwise)

Preceding gene: 54027515

Following gene: 54027512

Centisome position: 97.48

GC content: 64.92

Gene sequence:

>1662_bases
ATGACCGATGTCGCGTCGCAGGGCGCTGCCCAGGGAGACGACCGCCGCGTCCTGACCAACAGGCAGGGACATCCTGTCTT
CGACAACCAGAACCAGCGCACGGTGGGTGCCCGTGGACCCGCGACTCTGGAGAACTACCAGTTCTTGGAGAAGATCAGCC
ATTTCGATCGGGAACGCATCCCCGAGCGTGTCGTGCACGCCCGCGGGGCCGTCGCCTACGGCTATTTCGAGGCGACCGGC
AAGTGGGGTGACGAACCGATCGAGAATTACACCCGCGCAAAGATTTTCGCCGAAGCCGGCAAACGCACCGACCTCGCGAT
CCGTTTCTCCACCGTCATCGGCGGTCGGGATTCCTCGGAGGCCGCCCGCGACCCGCGCGGCTTCGCGATCAAGTTCTACA
CCGAGGACGGCAACTGGGATCTGGTCGGCAACAATCTCGGCGTGTTCTTCATCCGGGACGCGATCAAGTTCCCCGATGTC
ATCCACGCGCTCAAGCCCGACCCGGTGACCTTCCGGCAGGAGCCCGCGCGCATCTTCGACTTCATGTCGCAGACGCCCGA
GGCCATGCACATGCTGGTCAACCTGTTCAGCCCGCGCGGGATCCCGGCGAACTACCGCACCCAGCAGGGCTTCGGCGTGA
ACACCTACAAGTGGGTCAACGCCGAGGGCGTCACCCACCTGGTGAAGTACCACTGGATCCCGAAGGCGGGCGTGAAGAGC
CTCACCGAGGCCGACGCCGCCGCCATCCAGGCCCAGGATCTCGGGCACGCGAGCAAGGATCTGTACGAGCACATCGAGGC
CGGCGACTATCCCGAATGGGAGTTGCGGGTGCAGATCATGAGCGACGACGAGCATCCGGAGCTGAATTTCGATCCGCTCG
ACGACACCAAGGTCTGGCCGGAAAACGAGTTCCCGCCGAAACCGGTCGGCAAGATGGTGCTCAACCGGAACGTGAGCAAT
CACTTCCTGGAGAACGAGCAGATCTCCTTCGGCACCGGCGTGCTGGTCGACGGACTGGATTTCTCCGACGACAAGATGCT
GGTCGGCCGCACGTTCTCGTATTCGGACACCCAGCGCTACCGCGTCGGCCCGAACTATCTGCAGCTGCCGGTGAACCAGG
CCAAGAACGCGCACGTGGCCACCAATCAGCAGGGCGGGCCGATGGCCTACGGCATCGACGATGTCGGCGAGAACCCGCAC
GTCAACTACGAACCGTCGATCACCGGTGGTTTGCGGGAAGCCCAATATCCGACCCACGACGAACAGGGCCCGGAGATCAG
GGGCAGGCTCACCCGCAAGCGCATCCCGCGCACCAACGACTACGAGCAGGCCGGCCAGCGCTACCAGCTCATGGAGCAGT
GGGAGAAGGACGACCTGGTGACCAACCTGGTCGCCAACATCGGCCAGGCCACCCGCGAGGTGCAGGAGCGCATGGTGTGG
CACTTCTACATGTGCGACGACGAGCTGGGCGAACGCGTCGGCCAGGGGCTCGGCATCAGCGCCGACGACGTGCGCGGACT
GCCCCCGCTGCAGAGCCAGACGCTGTCCGACGAGGAATTGCAGCGCGCGGCCAACCTGGGCAAGAACGGCCCGCGCGACG
TCGAGGGGTTGCAGATGACCCACTGCGTCCCCGACGAACGCGAAGTGCACGCCGCCGCGTGA

Upstream 100 bases:

>100_bases
CCGCCGATTTGCTCGGTGCGATCAGCGGCCGCCCGGTGTTTGCGGGAGTAGCCTGCGGGTAGGCGGAAATGACCGGACTC
GCGAGCAGAGGAGCATTTCG

Downstream 100 bases:

>100_bases
TGGTGTGATCTCCGGTGGGGCGGGCGCGGGCCCGCCCCACCGTCGTCTGCCGGTACCCCGCCACGAGAGGACAGCCATGA
GCCGACCGGTTCGGATCGGA

Product: putative catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTDVASQGAAQGDDRRVLTNRQGHPVFDNQNQRTVGARGPATLENYQFLEKISHFDRERIPERVVHARGAVAYGYFEATG
KWGDEPIENYTRAKIFAEAGKRTDLAIRFSTVIGGRDSSEAARDPRGFAIKFYTEDGNWDLVGNNLGVFFIRDAIKFPDV
IHALKPDPVTFRQEPARIFDFMSQTPEAMHMLVNLFSPRGIPANYRTQQGFGVNTYKWVNAEGVTHLVKYHWIPKAGVKS
LTEADAAAIQAQDLGHASKDLYEHIEAGDYPEWELRVQIMSDDEHPELNFDPLDDTKVWPENEFPPKPVGKMVLNRNVSN
HFLENEQISFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRYRVGPNYLQLPVNQAKNAHVATNQQGGPMAYGIDDVGENPH
VNYEPSITGGLREAQYPTHDEQGPEIRGRLTRKRIPRTNDYEQAGQRYQLMEQWEKDDLVTNLVANIGQATREVQERMVW
HFYMCDDELGERVGQGLGISADDVRGLPPLQSQTLSDEELQRAANLGKNGPRDVEGLQMTHCVPDEREVHAAA

Sequences:

>Translated_553_residues
MTDVASQGAAQGDDRRVLTNRQGHPVFDNQNQRTVGARGPATLENYQFLEKISHFDRERIPERVVHARGAVAYGYFEATG
KWGDEPIENYTRAKIFAEAGKRTDLAIRFSTVIGGRDSSEAARDPRGFAIKFYTEDGNWDLVGNNLGVFFIRDAIKFPDV
IHALKPDPVTFRQEPARIFDFMSQTPEAMHMLVNLFSPRGIPANYRTQQGFGVNTYKWVNAEGVTHLVKYHWIPKAGVKS
LTEADAAAIQAQDLGHASKDLYEHIEAGDYPEWELRVQIMSDDEHPELNFDPLDDTKVWPENEFPPKPVGKMVLNRNVSN
HFLENEQISFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRYRVGPNYLQLPVNQAKNAHVATNQQGGPMAYGIDDVGENPH
VNYEPSITGGLREAQYPTHDEQGPEIRGRLTRKRIPRTNDYEQAGQRYQLMEQWEKDDLVTNLVANIGQATREVQERMVW
HFYMCDDELGERVGQGLGISADDVRGLPPLQSQTLSDEELQRAANLGKNGPRDVEGLQMTHCVPDEREVHAAA
>Mature_552_residues
TDVASQGAAQGDDRRVLTNRQGHPVFDNQNQRTVGARGPATLENYQFLEKISHFDRERIPERVVHARGAVAYGYFEATGK
WGDEPIENYTRAKIFAEAGKRTDLAIRFSTVIGGRDSSEAARDPRGFAIKFYTEDGNWDLVGNNLGVFFIRDAIKFPDVI
HALKPDPVTFRQEPARIFDFMSQTPEAMHMLVNLFSPRGIPANYRTQQGFGVNTYKWVNAEGVTHLVKYHWIPKAGVKSL
TEADAAAIQAQDLGHASKDLYEHIEAGDYPEWELRVQIMSDDEHPELNFDPLDDTKVWPENEFPPKPVGKMVLNRNVSNH
FLENEQISFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRYRVGPNYLQLPVNQAKNAHVATNQQGGPMAYGIDDVGENPHV
NYEPSITGGLREAQYPTHDEQGPEIRGRLTRKRIPRTNDYEQAGQRYQLMEQWEKDDLVTNLVANIGQATREVQERMVWH
FYMCDDELGERVGQGLGISADDVRGLPPLQSQTLSDEELQRAANLGKNGPRDVEGLQMTHCVPDEREVHAAA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=488, Percent_Identity=42.827868852459, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI48994891, Length=510, Percent_Identity=40.1960784313725, Blast_Score=349, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25147792, Length=486, Percent_Identity=43.0041152263374, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI25151141, Length=485, Percent_Identity=42.8865979381443, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71998444, Length=479, Percent_Identity=42.3799582463466, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6320462, Length=486, Percent_Identity=37.2427983539095, Blast_Score=307, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6321525, Length=520, Percent_Identity=31.5384615384615, Blast_Score=252, Evalue=1e-67,
Organism=Drosophila melanogaster, GI17981717, Length=485, Percent_Identity=41.4432989690722, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19920968, Length=488, Percent_Identity=39.344262295082, Blast_Score=364, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 62341; Mature: 62210

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVASQGAAQGDDRRVLTNRQGHPVFDNQNQRTVGARGPATLENYQFLEKISHFDRERI
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
PERVVHARGAVAYGYFEATGKWGDEPIENYTRAKIFAEAGKRTDLAIRFSTVIGGRDSSE
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHH
AARDPRGFAIKFYTEDGNWDLVGNNLGVFFIRDAIKFPDVIHALKPDPVTFRQEPARIFD
HHCCCCCEEEEEEEECCCEEEECCCCCEEEEECHHHCHHHHHHCCCCCCCCCCCHHHHHH
FMSQTPEAMHMLVNLFSPRGIPANYRTQQGFGVNTYKWVNAEGVTHLVKYHWIPKAGVKS
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHH
LTEADAAAIQAQDLGHASKDLYEHIEAGDYPEWELRVQIMSDDEHPELNFDPLDDTKVWP
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
ENEFPPKPVGKMVLNRNVSNHFLENEQISFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRY
CCCCCCCHHHHHHHHCCHHHHHCCCCCEECCCCEEEECCCCCCCCEEEEEEECCCCCCEE
RVGPNYLQLPVNQAKNAHVATNQQGGPMAYGIDDVGENPHVNYEPSITGGLREAQYPTHD
ECCCCEEEECCCCCCCCEEEECCCCCCEEECHHHCCCCCCCCCCCCCCCCCHHCCCCCCC
EQGPEIRGRLTRKRIPRTNDYEQAGQRYQLMEQWEKDDLVTNLVANIGQATREVQERMVW
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEE
HFYMCDDELGERVGQGLGISADDVRGLPPLQSQTLSDEELQRAANLGKNGPRDVEGLQMT
EEEECCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEE
HCVPDEREVHAAA
ECCCCCCCCCCCC
>Mature Secondary Structure 
TDVASQGAAQGDDRRVLTNRQGHPVFDNQNQRTVGARGPATLENYQFLEKISHFDRERI
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
PERVVHARGAVAYGYFEATGKWGDEPIENYTRAKIFAEAGKRTDLAIRFSTVIGGRDSSE
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHH
AARDPRGFAIKFYTEDGNWDLVGNNLGVFFIRDAIKFPDVIHALKPDPVTFRQEPARIFD
HHCCCCCEEEEEEEECCCEEEECCCCCEEEEECHHHCHHHHHHCCCCCCCCCCCHHHHHH
FMSQTPEAMHMLVNLFSPRGIPANYRTQQGFGVNTYKWVNAEGVTHLVKYHWIPKAGVKS
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHH
LTEADAAAIQAQDLGHASKDLYEHIEAGDYPEWELRVQIMSDDEHPELNFDPLDDTKVWP
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
ENEFPPKPVGKMVLNRNVSNHFLENEQISFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRY
CCCCCCCHHHHHHHHCCHHHHHCCCCCEECCCCEEEECCCCCCCCEEEEEEECCCCCCEE
RVGPNYLQLPVNQAKNAHVATNQQGGPMAYGIDDVGENPHVNYEPSITGGLREAQYPTHD
ECCCCEEEECCCCCCCCEEEECCCCCCEEECHHHCCCCCCCCCCCCCCCCCHHCCCCCCC
EQGPEIRGRLTRKRIPRTNDYEQAGQRYQLMEQWEKDDLVTNLVANIGQATREVQERMVW
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEE
HFYMCDDELGERVGQGLGISADDVRGLPPLQSQTLSDEELQRAANLGKNGPRDVEGLQMT
EEEECCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEE
HCVPDEREVHAAA
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]