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The map label for this gene is hmp [H]

Identifier: 54027379

GI number: 54027379

Start: 5709599

End: 5710771

Strand: Reverse

Name: hmp [H]

Synonym: nfa54050

Alternate gene names: 54027379

Gene position: 5710771-5709599 (Counterclockwise)

Preceding gene: 54027380

Following gene: 54027376

Centisome position: 94.84

GC content: 67.6

Gene sequence:

>1173_bases
ATGGATTCGCGGTCCGTCGCTCTGATCCGAACGACGTTCAAGGCGGTCGCCGCGGACGATGCGGGACCGGACGAGCTGGC
CAGGACGTTCTACGCGATCCTGTTCACCGACCACCCACAGATCCGCGACTTCTTCCCCGCCGCGATGGACGTCCAGCGCG
ACCGGCTGGTGAAGGCCATCTCCTATGCGCTCGACCGCCTGGAGGAGCCGGACAAACTGCTGCCCTTCCTCGCCCAACTC
GGCCGTGACCACCGCAAATACGGCGTGCGCCGCGAGCACTACGCCGCCGTCGCCGACTCGCTCAAGGCCGCGGTGCGACG
ATGCGCGGGCACCGAGATGTGGACCGACGAGGTGGACCGCGCCTGGGACGAGGGCCTGGCGCTGATCTCCGATGCCATGA
TCGGCGCGGCCGAGAAGGAGACCTCGCCGTCCGCGTGGACCGGGCGCGTCGTCGAAACCCGCCAGGTGTTGCGCAATCTC
ACGATCGTCCGGCTGCAACTGGACCAGCCGATGGAATACGCCGCAGGCCAGTACATGAGCGTCCAGATTCCCTCCCGGCC
ACGGATGTGGCGGTATCTCTCGCCCGCCGTTCCGGCGAATCCGCAGGGCGAGATCGAATTCCACGTCCGCAGCATCCTCG
GTGGCTGGGTGAGCCCCGCGGTGGTGAGTCAGACCCGCGTCGGCGACCAGTGGCTGATCGGCTCACCGCTGGGCGGGCTG
GGCGTCCCGCGCAATGCCAAACGGAAGATGCTGATGATCGGTTGCGGTACCGGTATCGCGCCGTTGCGCGCGCAATTGCT
GGAAATGGCGCAGCGGCGCAGTAATCCCAAGGTGCACCTGTTCGTCGGCGGTCACCACCCGTGCGATCTCTACGATCTGG
AGATGCTCAGCACCCTGGCGGTGACGAACAAGTGGCTCACGGTCACGCCGGTCACCGAGCACGAGGAGAATCCCTGGTGG
TTCTACCGCGCTCCGGACGAGCCGGAGCCGGTGTTCCCCGCGCTCGAACCGCGGCTGACCGGTCAGCTCGGCAAGGTCGT
CGCCGAGGCGGGGCCGTGGGCCGACCGTGACGTGCAGATCGCCGGCTCGCCCTCGATGGTGCAGACCACCAAGTTCCGCC
TGATGGCCGCGGGCATCCCGGCCAAGAACATCCGGCACGACCCGCTGTTCTGA

Upstream 100 bases:

>100_bases
CTCGCCTACACTCCAACCATCGGCTGCTGTCGAGTGTCCCGCAGCACCTCACTCGCCGGCGCGGTCAGTGTTTCGAGTGC
GAAATGGGGTTGTGAGGCAC

Downstream 100 bases:

>100_bases
GCCGTCAAACCCCTTCGTACTGGATGCGGTCGGCGGGAGTGCCGGTCTCGATCAGCCGGTCCACCGTCGCCCGCGTCATG
GCCGGTGAGCCGCAGACCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MDSRSVALIRTTFKAVAADDAGPDELARTFYAILFTDHPQIRDFFPAAMDVQRDRLVKAISYALDRLEEPDKLLPFLAQL
GRDHRKYGVRREHYAAVADSLKAAVRRCAGTEMWTDEVDRAWDEGLALISDAMIGAAEKETSPSAWTGRVVETRQVLRNL
TIVRLQLDQPMEYAAGQYMSVQIPSRPRMWRYLSPAVPANPQGEIEFHVRSILGGWVSPAVVSQTRVGDQWLIGSPLGGL
GVPRNAKRKMLMIGCGTGIAPLRAQLLEMAQRRSNPKVHLFVGGHHPCDLYDLEMLSTLAVTNKWLTVTPVTEHEENPWW
FYRAPDEPEPVFPALEPRLTGQLGKVVAEAGPWADRDVQIAGSPSMVQTTKFRLMAAGIPAKNIRHDPLF

Sequences:

>Translated_390_residues
MDSRSVALIRTTFKAVAADDAGPDELARTFYAILFTDHPQIRDFFPAAMDVQRDRLVKAISYALDRLEEPDKLLPFLAQL
GRDHRKYGVRREHYAAVADSLKAAVRRCAGTEMWTDEVDRAWDEGLALISDAMIGAAEKETSPSAWTGRVVETRQVLRNL
TIVRLQLDQPMEYAAGQYMSVQIPSRPRMWRYLSPAVPANPQGEIEFHVRSILGGWVSPAVVSQTRVGDQWLIGSPLGGL
GVPRNAKRKMLMIGCGTGIAPLRAQLLEMAQRRSNPKVHLFVGGHHPCDLYDLEMLSTLAVTNKWLTVTPVTEHEENPWW
FYRAPDEPEPVFPALEPRLTGQLGKVVAEAGPWADRDVQIAGSPSMVQTTKFRLMAAGIPAKNIRHDPLF
>Mature_390_residues
MDSRSVALIRTTFKAVAADDAGPDELARTFYAILFTDHPQIRDFFPAAMDVQRDRLVKAISYALDRLEEPDKLLPFLAQL
GRDHRKYGVRREHYAAVADSLKAAVRRCAGTEMWTDEVDRAWDEGLALISDAMIGAAEKETSPSAWTGRVVETRQVLRNL
TIVRLQLDQPMEYAAGQYMSVQIPSRPRMWRYLSPAVPANPQGEIEFHVRSILGGWVSPAVVSQTRVGDQWLIGSPLGGL
GVPRNAKRKMLMIGCGTGIAPLRAQLLEMAQRRSNPKVHLFVGGHHPCDLYDLEMLSTLAVTNKWLTVTPVTEHEENPWW
FYRAPDEPEPVFPALEPRLTGQLGKVVAEAGPWADRDVQIAGSPSMVQTTKFRLMAAGIPAKNIRHDPLF

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI2367314, Length=247, Percent_Identity=25.5060728744939, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788903, Length=410, Percent_Identity=22.1951219512195, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43554; Mature: 43554

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRSVALIRTTFKAVAADDAGPDELARTFYAILFTDHPQIRDFFPAAMDVQRDRLVKAI
CCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHCHHHHHHHHHHHHHHH
SYALDRLEEPDKLLPFLAQLGRDHRKYGVRREHYAAVADSLKAAVRRCAGTEMWTDEVDR
HHHHHHCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AWDEGLALISDAMIGAAEKETSPSAWTGRVVETRQVLRNLTIVRLQLDQPMEYAAGQYMS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCHHHHCCCEEE
VQIPSRPRMWRYLSPAVPANPQGEIEFHVRSILGGWVSPAVVSQTRVGDQWLIGSPLGGL
EEECCCCCHHHHCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCC
GVPRNAKRKMLMIGCGTGIAPLRAQLLEMAQRRSNPKVHLFVGGHHPCDLYDLEMLSTLA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
VTNKWLTVTPVTEHEENPWWFYRAPDEPEPVFPALEPRLTGQLGKVVAEAGPWADRDVQI
HCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
AGSPSMVQTTKFRLMAAGIPAKNIRHDPLF
CCCCCCCHHHHEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDSRSVALIRTTFKAVAADDAGPDELARTFYAILFTDHPQIRDFFPAAMDVQRDRLVKAI
CCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHCHHHHHHHHHHHHHHH
SYALDRLEEPDKLLPFLAQLGRDHRKYGVRREHYAAVADSLKAAVRRCAGTEMWTDEVDR
HHHHHHCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AWDEGLALISDAMIGAAEKETSPSAWTGRVVETRQVLRNLTIVRLQLDQPMEYAAGQYMS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCHHHHCCCEEE
VQIPSRPRMWRYLSPAVPANPQGEIEFHVRSILGGWVSPAVVSQTRVGDQWLIGSPLGGL
EEECCCCCHHHHCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCC
GVPRNAKRKMLMIGCGTGIAPLRAQLLEMAQRRSNPKVHLFVGGHHPCDLYDLEMLSTLA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
VTNKWLTVTPVTEHEENPWWFYRAPDEPEPVFPALEPRLTGQLGKVVAEAGPWADRDVQI
HCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
AGSPSMVQTTKFRLMAAGIPAKNIRHDPLF
CCCCCCCHHHHEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377 [H]