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The map label for this gene is hipA [C]

Identifier: 54027298

GI number: 54027298

Start: 5626724

End: 5627923

Strand: Reverse

Name: hipA [C]

Synonym: nfa53240

Alternate gene names: 54027298

Gene position: 5627923-5626724 (Counterclockwise)

Preceding gene: 54027299

Following gene: 54027297

Centisome position: 93.47

GC content: 67.08

Gene sequence:

>1200_bases
GTGTACAAGTGCGGTCGCCTGGCGGGAACCCTTCGCAGGGACGGTGACGACGTGGTCTTCACCTACCTCGAGGAGTATCG
AGCCGACCCCGAGACACCGCCGATCGCGTTCACCCTGCCCAAGCATTCCGAGGCCGTCCGAACGACCGGCGGTTCGGTCC
CACCGTTCTTCGCCGGCCTGCTCCCCGAGGGAGCTCGCTTGGTCGCGATCACGGCGCTCACCAGAACGAGCGAGGACGAC
CACCTCAGCCTGCTTCTCGCGGTCGGTGCGGACACCGTCGGCGACGTCCAGGTGCTCCCCACCGGGCTGTCTCTCACCGA
GCCGCCGCCACTGTTCGGCGAAGATCCCGCCACCGCGGACTTCGCCGAGGTGTTTGCCCGGGCCACCGCGATCACCGGCG
ATGAGTTCGACCGCACCGCACTGCCGGGGATTCAGGTGAAGGTGTCCGCCCGGATGATCTCCACTCCCGTGCGAACCGGG
CATGGGGCAGCCATCCTGAAACTGAATCCACCGGAGTTCCCCCGCCTGGTGGAGAACGAGAACTTCTTTCTCGACATGGC
CGCGGAGTGTGGAATCCGGGTCCCACCGCATCAACTCGCGATCGACCGGCTTGGGCGAGCCGGACTGTTCGTCGAACGCT
TCGACCGAGTGGTGGAGGGAGACGGGATACGGCGCCTCGCGCAAGAGGATGCCTGCCAGGTACTCGGCAGGTATCCGGCC
GCGAAGTACCGGATATCGTTGCAGGAAGCGATCAAGGGACTCGGGCAGGCGGTGGAGGCCGGGGAAGGATCGCGCCGGGC
CGCCATTCTCACCATGCTCGAGATCGCGGCGTTCAGTTACCTCATCGGCAACGGCGATTTACACGGCAAGAACCTCTCCA
TCCTTCGGGCGCCGAGCGGGATCTGGGAGGTCACCCCCGCCTACGACCTGCTCACCACGCAGCCGTACCTGTCCTGGAAA
GACCCGATGGCGCTGGCACTGTATGGCCGGAATGCCAGGCTCGGGCACCGATGGTGGATGGAGGCCGCCGAGCGTCTCGG
TGTTCCCCGGCGCGCGCTGGCCCGCAGCCTGGACCGCATCAGCGAGGCCGCCCAACCGTGGATCGGGAGGCTGGGCGAGA
TCGGGTTCGACGAAGCCTGGACGCGACGACTCGCGGAGCTGATCGAGCAGCGGCGGCAGGAGTTGTCCGCCCCCGAGTGA

Upstream 100 bases:

>100_bases
GCCATCACCGGCAGGGCCGCCAGGGTCCGCCCGGCACAGGAGGTCGACGATGAGCAACTGGCCTGAGCCCGGACGCCTCC
GCGACGTCGAGTCTGCCGAT

Downstream 100 bases:

>100_bases
GTCCGATCGAGCAGTTGCCCCTCTGTGAGGGCCGGTGGATGGGAGACTGGCCGTGGGGGTCGCGTCATATGGGTGGACCG
GATTCGGATGAACGAGAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MYKCGRLAGTLRRDGDDVVFTYLEEYRADPETPPIAFTLPKHSEAVRTTGGSVPPFFAGLLPEGARLVAITALTRTSEDD
HLSLLLAVGADTVGDVQVLPTGLSLTEPPPLFGEDPATADFAEVFARATAITGDEFDRTALPGIQVKVSARMISTPVRTG
HGAAILKLNPPEFPRLVENENFFLDMAAECGIRVPPHQLAIDRLGRAGLFVERFDRVVEGDGIRRLAQEDACQVLGRYPA
AKYRISLQEAIKGLGQAVEAGEGSRRAAILTMLEIAAFSYLIGNGDLHGKNLSILRAPSGIWEVTPAYDLLTTQPYLSWK
DPMALALYGRNARLGHRWWMEAAERLGVPRRALARSLDRISEAAQPWIGRLGEIGFDEAWTRRLAELIEQRRQELSAPE

Sequences:

>Translated_399_residues
MYKCGRLAGTLRRDGDDVVFTYLEEYRADPETPPIAFTLPKHSEAVRTTGGSVPPFFAGLLPEGARLVAITALTRTSEDD
HLSLLLAVGADTVGDVQVLPTGLSLTEPPPLFGEDPATADFAEVFARATAITGDEFDRTALPGIQVKVSARMISTPVRTG
HGAAILKLNPPEFPRLVENENFFLDMAAECGIRVPPHQLAIDRLGRAGLFVERFDRVVEGDGIRRLAQEDACQVLGRYPA
AKYRISLQEAIKGLGQAVEAGEGSRRAAILTMLEIAAFSYLIGNGDLHGKNLSILRAPSGIWEVTPAYDLLTTQPYLSWK
DPMALALYGRNARLGHRWWMEAAERLGVPRRALARSLDRISEAAQPWIGRLGEIGFDEAWTRRLAELIEQRRQELSAPE
>Mature_399_residues
MYKCGRLAGTLRRDGDDVVFTYLEEYRADPETPPIAFTLPKHSEAVRTTGGSVPPFFAGLLPEGARLVAITALTRTSEDD
HLSLLLAVGADTVGDVQVLPTGLSLTEPPPLFGEDPATADFAEVFARATAITGDEFDRTALPGIQVKVSARMISTPVRTG
HGAAILKLNPPEFPRLVENENFFLDMAAECGIRVPPHQLAIDRLGRAGLFVERFDRVVEGDGIRRLAQEDACQVLGRYPA
AKYRISLQEAIKGLGQAVEAGEGSRRAAILTMLEIAAFSYLIGNGDLHGKNLSILRAPSGIWEVTPAYDLLTTQPYLSWK
DPMALALYGRNARLGHRWWMEAAERLGVPRRALARSLDRISEAAQPWIGRLGEIGFDEAWTRRLAELIEQRRQELSAPE

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=322, Percent_Identity=27.9503105590062, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 43747; Mature: 43747

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKCGRLAGTLRRDGDDVVFTYLEEYRADPETPPIAFTLPKHSEAVRTTGGSVPPFFAGL
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCCCHHHHHH
LPEGARLVAITALTRTSEDDHLSLLLAVGADTVGDVQVLPTGLSLTEPPPLFGEDPATAD
CCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
FAEVFARATAITGDEFDRTALPGIQVKVSARMISTPVRTGHGAAILKLNPPEFPRLVENE
HHHHHHHHHHCCCCCCCHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEECCCCCCHHHCCC
NFFLDMAAECGIRVPPHQLAIDRLGRAGLFVERFDRVVEGDGIRRLAQEDACQVLGRYPA
CEEEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
AKYRISLQEAIKGLGQAVEAGEGSRRAAILTMLEIAAFSYLIGNGDLHGKNLSILRAPSG
HHEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
IWEVTPAYDLLTTQPYLSWKDPMALALYGRNARLGHRWWMEAAERLGVPRRALARSLDRI
CEECCCCHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SEAAQPWIGRLGEIGFDEAWTRRLAELIEQRRQELSAPE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYKCGRLAGTLRRDGDDVVFTYLEEYRADPETPPIAFTLPKHSEAVRTTGGSVPPFFAGL
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCCCHHHHHH
LPEGARLVAITALTRTSEDDHLSLLLAVGADTVGDVQVLPTGLSLTEPPPLFGEDPATAD
CCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
FAEVFARATAITGDEFDRTALPGIQVKVSARMISTPVRTGHGAAILKLNPPEFPRLVENE
HHHHHHHHHHCCCCCCCHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEECCCCCCHHHCCC
NFFLDMAAECGIRVPPHQLAIDRLGRAGLFVERFDRVVEGDGIRRLAQEDACQVLGRYPA
CEEEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
AKYRISLQEAIKGLGQAVEAGEGSRRAAILTMLEIAAFSYLIGNGDLHGKNLSILRAPSG
HHEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
IWEVTPAYDLLTTQPYLSWKDPMALALYGRNARLGHRWWMEAAERLGVPRRALARSLDRI
CEECCCCHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SEAAQPWIGRLGEIGFDEAWTRRLAELIEQRRQELSAPE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]