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The map label for this gene is yciC [H]

Identifier: 54027292

GI number: 54027292

Start: 5619757

End: 5620923

Strand: Reverse

Name: yciC [H]

Synonym: nfa53180

Alternate gene names: 54027292

Gene position: 5620923-5619757 (Counterclockwise)

Preceding gene: 54027297

Following gene: 54027288

Centisome position: 93.35

GC content: 69.15

Gene sequence:

>1167_bases
ATGATTACCATTTACAGGATGACGACTTCATCGCCTTCCGACCTGCTGCCCGTCACCGTGCTCTCCGGATTCCTCGGCGC
GGGTAAGACCACCCTGCTCAACCACATCCTCGCCAACCGGGAGGGTCGCCGCGTCGCGGTGATCGTCAACGACATGAGCG
AGGTGAACATCGACGCGGCGCTCGTCGCGGGCCAGGGCCACCTGGACCGCACCGAGGAGAAGCTGGTGGAACTGACCAAC
GGCTGCATCTGCTGCACCCTGCGCGAGGACCTCATCGAGTCGGTGGGCAAGCTCGCGCGCGAGGGCCGCTTCGACCAGCT
GGTCATCGAGTCGACCGGCATCTCCGAGCCGATGCCGGTGGCGGCGAGCTTCGAATGGGAATTCGAGGACGGGTTCCGCC
TCGGCGACCTCGCGCGGCTGGACACGATGGTCACCGTGGTGGACGCCTCGACCTTCCTGGCCGAGGTGGTGCGCGGCCAC
ACGCTGGCCTCGCGGGATCTCCAGGCCGGGGAGGGCGACGAGCGCACCATCGCCGACCTGCTCGTCGACCAGGTGGAATT
CGCCGACGTGCTGTTGCTCAACAAGACCGATCTGGTCAGCGAGAACGCCGCGGGCACCGTCGAGGCCACCCTGCGGCGGA
TGAACCCGCGCGCCCGTGTGCTGCGCACCGCACACGGCGTGGTCGATCTCGCCGAAGTGCTCGGCACCGGGCGCTACAAC
CCGGTGCTGGCCGCCGCATCCGAGGGCTGGACCGAGGAACTGGCGGGCGGGCATGTTCCCGAGACCGAGGAGTACGGCAT
CCGCAGCCTCACCTTCACCGCCGAGCGGCCGTTCCATCCAGCGCGCCTGGCGGCCGTGCTCGACCAGCTGCGGGGGCTGT
TGCGCAGCAAGGGTTTCTGCTGGATCGCCAGCCGCAGCCAGTTCGCCGCGCTCTGGTCGCAGGCCGGTCCGAACCTCAGC
TTCGAACCGGCCTCCTGGTGGTCGGCGTTGGACATCCCGCCGGGCCAGGAGATCGTCTTCATCGGTGTGAAGCTCGACGT
CGACGGGCTGCGTGCCCAGCTGGCCGACGCGCTGCTCACCGACGCCGAGTTCGCCGCGGGCCCGGCCGCCTGGGCGACCT
ACCCGGATCCGTTTCCGGCGTGGGGCGAGCTGCACGAGCACGCCTGA

Upstream 100 bases:

>100_bases
GCGTCTGGCCTTCGGCGGGGAGCGGCAACAGCTTCACAGATGTGCACCATACGGTGGCGCGGCGGGGAATGGGGCAGCCG
GTGCGCGGTGCTAATTGAAA

Downstream 100 bases:

>100_bases
GCGCCGCTAACGCGGGGCGAGGAACAGGGTCTGGGTGCTGCGTCCGAGCGGGCCCTTCTCGTCGAACAGCGCCGACTCGG
CCATGCCGAGACCGCTGGGC

Product: putative GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MITIYRMTTSSPSDLLPVTVLSGFLGAGKTTLLNHILANREGRRVAVIVNDMSEVNIDAALVAGQGHLDRTEEKLVELTN
GCICCTLREDLIESVGKLAREGRFDQLVIESTGISEPMPVAASFEWEFEDGFRLGDLARLDTMVTVVDASTFLAEVVRGH
TLASRDLQAGEGDERTIADLLVDQVEFADVLLLNKTDLVSENAAGTVEATLRRMNPRARVLRTAHGVVDLAEVLGTGRYN
PVLAAASEGWTEELAGGHVPETEEYGIRSLTFTAERPFHPARLAAVLDQLRGLLRSKGFCWIASRSQFAALWSQAGPNLS
FEPASWWSALDIPPGQEIVFIGVKLDVDGLRAQLADALLTDAEFAAGPAAWATYPDPFPAWGELHEHA

Sequences:

>Translated_388_residues
MITIYRMTTSSPSDLLPVTVLSGFLGAGKTTLLNHILANREGRRVAVIVNDMSEVNIDAALVAGQGHLDRTEEKLVELTN
GCICCTLREDLIESVGKLAREGRFDQLVIESTGISEPMPVAASFEWEFEDGFRLGDLARLDTMVTVVDASTFLAEVVRGH
TLASRDLQAGEGDERTIADLLVDQVEFADVLLLNKTDLVSENAAGTVEATLRRMNPRARVLRTAHGVVDLAEVLGTGRYN
PVLAAASEGWTEELAGGHVPETEEYGIRSLTFTAERPFHPARLAAVLDQLRGLLRSKGFCWIASRSQFAALWSQAGPNLS
FEPASWWSALDIPPGQEIVFIGVKLDVDGLRAQLADALLTDAEFAAGPAAWATYPDPFPAWGELHEHA
>Mature_388_residues
MITIYRMTTSSPSDLLPVTVLSGFLGAGKTTLLNHILANREGRRVAVIVNDMSEVNIDAALVAGQGHLDRTEEKLVELTN
GCICCTLREDLIESVGKLAREGRFDQLVIESTGISEPMPVAASFEWEFEDGFRLGDLARLDTMVTVVDASTFLAEVVRGH
TLASRDLQAGEGDERTIADLLVDQVEFADVLLLNKTDLVSENAAGTVEATLRRMNPRARVLRTAHGVVDLAEVLGTGRYN
PVLAAASEGWTEELAGGHVPETEEYGIRSLTFTAERPFHPARLAAVLDQLRGLLRSKGFCWIASRSQFAALWSQAGPNLS
FEPASWWSALDIPPGQEIVFIGVKLDVDGLRAQLADALLTDAEFAAGPAAWATYPDPFPAWGELHEHA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=378, Percent_Identity=30.4232804232804, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI148727351, Length=378, Percent_Identity=30.1587301587302, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI33469141, Length=378, Percent_Identity=30.1587301587302, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI126722884, Length=367, Percent_Identity=30.2452316076294, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI223941779, Length=353, Percent_Identity=30.8781869688385, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI223941776, Length=357, Percent_Identity=29.6918767507003, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI119120938, Length=364, Percent_Identity=26.9230769230769, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI87082430, Length=354, Percent_Identity=31.9209039548023, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788499, Length=303, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=236, Percent_Identity=25.8474576271186, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 42103; Mature: 42103

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIYRMTTSSPSDLLPVTVLSGFLGAGKTTLLNHILANREGRRVAVIVNDMSEVNIDAA
CEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
LVAGQGHLDRTEEKLVELTNGCICCTLREDLIESVGKLAREGRFDQLVIESTGISEPMPV
EEECCCCCCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
AASFEWEFEDGFRLGDLARLDTMVTVVDASTFLAEVVRGHTLASRDLQAGEGDERTIADL
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LVDQVEFADVLLLNKTDLVSENAAGTVEATLRRMNPRARVLRTAHGVVDLAEVLGTGRYN
HHHHHHHHHEEEECCHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
PVLAAASEGWTEELAGGHVPETEEYGIRSLTFTAERPFHPARLAAVLDQLRGLLRSKGFC
CEEEECCCCCHHHHCCCCCCCCHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEE
WIASRSQFAALWSQAGPNLSFEPASWWSALDIPPGQEIVFIGVKLDVDGLRAQLADALLT
EEECCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHH
DAEFAAGPAAWATYPDPFPAWGELHEHA
CCHHCCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MITIYRMTTSSPSDLLPVTVLSGFLGAGKTTLLNHILANREGRRVAVIVNDMSEVNIDAA
CEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
LVAGQGHLDRTEEKLVELTNGCICCTLREDLIESVGKLAREGRFDQLVIESTGISEPMPV
EEECCCCCCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
AASFEWEFEDGFRLGDLARLDTMVTVVDASTFLAEVVRGHTLASRDLQAGEGDERTIADL
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LVDQVEFADVLLLNKTDLVSENAAGTVEATLRRMNPRARVLRTAHGVVDLAEVLGTGRYN
HHHHHHHHHEEEECCHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
PVLAAASEGWTEELAGGHVPETEEYGIRSLTFTAERPFHPARLAAVLDQLRGLLRSKGFC
CEEEECCCCCHHHHCCCCCCCCHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEE
WIASRSQFAALWSQAGPNLSFEPASWWSALDIPPGQEIVFIGVKLDVDGLRAQLADALLT
EEECCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHH
DAEFAAGPAAWATYPDPFPAWGELHEHA
CCHHCCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]