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The map label for this gene is degP [H]

Identifier: 54027199

GI number: 54027199

Start: 5518112

End: 5519206

Strand: Reverse

Name: degP [H]

Synonym: nfa52250

Alternate gene names: 54027199

Gene position: 5519206-5518112 (Counterclockwise)

Preceding gene: 54027202

Following gene: 54027195

Centisome position: 91.66

GC content: 74.52

Gene sequence:

>1095_bases
ATGCAGGACGAACCGCGCGGCAGCGGCGGCCGATGGTCCGCGCTGCTGGTGGCGGCCGTGCTCGCCCTGGCCGGGTTCCT
CGGTTTCCGCGGTGAGCTGCCCGGATGGCCGTTCGGAGACACCGGGACCACGGCCGCGCCGACGGTCCGGCCGCCGAATC
CGCCGCTCGACCAGGCTGCCGTCGCGGCCGAGGTCACGCCGGCGCTGGTGAACATCAGCACCCGGACCCGCCCGCTCGGC
CAGGGCGCGGCCGGGACCGGCATCGTGCTGACCGCCGACGGGCAGGTGCTCACCAGCCATCACGTGGTGAAAGGCGCCGA
GCAGGTCGTGGTCACCACGCAGGCGACCGGCGCCGAGTATCGCGCGACCGTGCTCGGCTACGACTCGACCGCCGACATCG
CCCTGCTGTCGCTGCCGGGGGCGAACGGCCTGCCGACCGCCCGGCTGGGCAGTTCGTCGAGCGTGCGGGTGCGTGACGAG
GTGCTTGCCCTGGGCAACGCCGGTGGCACCGGCGGCCCGCCGACCGCGACACCCGGCCTGGTCACCGCGCTCAACAGCAC
CATCGTGGCGCTCAACGCCGCGGATCTGTCGCGGAAGGCGTTGCGCGGGATGGTGGAGGTGGCCGCCCCGGTCAGCTCCG
GGCAGTCCGGGGGCGCACTGGTCGACTGGCAGGGCGCGGTGGTCGGCGTCGTCACCGCGTCGTCGGGGGAGGCGGCGGCC
GAACTGGAACGGCCGAACGGCTACGCGGTGCCCATCGACACCGCCATGCGAGTGGTGCGCCAGATCCGGTCCGGCATCCC
CACCGACACCGTGCACATCGGCCCGACCGCGACCCTCGGTGTGCTCATCTCCGACGCCAGCCCCAGTGGCGCCCGCATCG
ACGTGGCCCTCTACGGCCTGCCCGCCTACGCCGCCGGTCTCGCCGACGGCGAGGTGATCGTCTCGATCGACGGCCGCCCG
ATCGGCTCGGCGCGAGTGCTGCGCACGGCCATCGACCGGCGCAGGCCGGGGGAGACCGTGCGCCTCGGCGTGCTCGGCGT
CGACGGGGTGGAGCGCACGGTCACCGTGGAACTGGGCCTCGGCACGCCGAACTGA

Upstream 100 bases:

>100_bases
TGCCTACCGTCGCATGCACCGGATTGCCAACCGATCGCCGTCCCCGGCCGCCACAATGGGATTCGTCACGGCCGTCGGGC
CAGGTGAGGGTGGAGGGCGC

Downstream 100 bases:

>100_bases
GCCTCACACCAGGCTCAGCCAGTAGTCCTGGAAGCGGAGGAACACCAGCAGCAGGACCACCGCGTAGAACAGGGCGACCA
GGGTCCACCGCCATTCGGCC

Product: putative protease

Products: NA

Alternate protein names: Antigen htrA [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MQDEPRGSGGRWSALLVAAVLALAGFLGFRGELPGWPFGDTGTTAAPTVRPPNPPLDQAAVAAEVTPALVNISTRTRPLG
QGAAGTGIVLTADGQVLTSHHVVKGAEQVVVTTQATGAEYRATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDE
VLALGNAGGTGGPPTATPGLVTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVVTASSGEAAA
ELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGARIDVALYGLPAYAAGLADGEVIVSIDGRP
IGSARVLRTAIDRRRPGETVRLGVLGVDGVERTVTVELGLGTPN

Sequences:

>Translated_364_residues
MQDEPRGSGGRWSALLVAAVLALAGFLGFRGELPGWPFGDTGTTAAPTVRPPNPPLDQAAVAAEVTPALVNISTRTRPLG
QGAAGTGIVLTADGQVLTSHHVVKGAEQVVVTTQATGAEYRATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDE
VLALGNAGGTGGPPTATPGLVTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVVTASSGEAAA
ELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGARIDVALYGLPAYAAGLADGEVIVSIDGRP
IGSARVLRTAIDRRRPGETVRLGVLGVDGVERTVTVELGLGTPN
>Mature_364_residues
MQDEPRGSGGRWSALLVAAVLALAGFLGFRGELPGWPFGDTGTTAAPTVRPPNPPLDQAAVAAEVTPALVNISTRTRPLG
QGAAGTGIVLTADGQVLTSHHVVKGAEQVVVTTQATGAEYRATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDE
VLALGNAGGTGGPPTATPGLVTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVVTASSGEAAA
ELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGARIDVALYGLPAYAAGLADGEVIVSIDGRP
IGSARVLRTAIDRRRPGETVRLGVLGVDGVERTVTVELGLGTPN

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=358, Percent_Identity=27.6536312849162, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4506141, Length=318, Percent_Identity=27.6729559748428, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI22129776, Length=303, Percent_Identity=26.0726072607261, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789629, Length=272, Percent_Identity=29.7794117647059, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786356, Length=291, Percent_Identity=28.8659793814433, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789630, Length=305, Percent_Identity=27.5409836065574, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 36539; Mature: 36539

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDEPRGSGGRWSALLVAAVLALAGFLGFRGELPGWPFGDTGTTAAPTVRPPNPPLDQAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VAAEVTPALVNISTRTRPLGQGAAGTGIVLTADGQVLTSHHVVKGAEQVVVTTQATGAEY
HHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECCCEEECHHHHCCCCEEEEEEECCCCCE
RATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDEVLALGNAGGTGGPPTATPGL
EEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHH
VTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVVTASSGEAAA
HHHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCHH
ELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGARIDVALYGL
EEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEECC
PAYAAGLADGEVIVSIDGRPIGSARVLRTAIDRRRPGETVRLGVLGVDGVERTVTVELGL
CHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEEC
GTPN
CCCC
>Mature Secondary Structure
MQDEPRGSGGRWSALLVAAVLALAGFLGFRGELPGWPFGDTGTTAAPTVRPPNPPLDQAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VAAEVTPALVNISTRTRPLGQGAAGTGIVLTADGQVLTSHHVVKGAEQVVVTTQATGAEY
HHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECCCEEECHHHHCCCCEEEEEEECCCCCE
RATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDEVLALGNAGGTGGPPTATPGL
EEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHH
VTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVVTASSGEAAA
HHHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCHH
ELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGARIDVALYGL
EEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEECC
PAYAAGLADGEVIVSIDGRPIGSARVLRTAIDRRRPGETVRLGVLGVDGVERTVTVELGL
CHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEEC
GTPN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8027347 [H]