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The map label for this gene is sucD [H]

Identifier: 54026964

GI number: 54026964

Start: 5205179

End: 5206093

Strand: Reverse

Name: sucD [H]

Synonym: nfa49900

Alternate gene names: 54026964

Gene position: 5206093-5205179 (Counterclockwise)

Preceding gene: 54026965

Following gene: 54026963

Centisome position: 86.46

GC content: 67.43

Gene sequence:

>915_bases
ATGTCAATCTTCCTGAACAAGGACTCCAAGGTCATCGTCCAGGGCATCACCGGCGGTGAAGGCACCAAGCACACCGCGCT
GATGCTCAAGGCGGGCACCAAGATCGTCGGCGGCGTCAACGCGCGCAAGGCGGGCACCACCGTCTCGCACACCGACAAGG
ACGGCAACGCCGTCGAGCTGCCGGTCTTCGGCACCGTCGCCGAGGCCATCAAGGAGACCGGCGCCGACGTCTCCATCGCG
TTCGTGCCGCCGAAGTTCGCCAAGGACGCCATCATCGAGGCCATCGACGCGGAGATCCCGCTGCTGGTGGTCATCACCGA
GGGCATCCCCGTGCAGGACACCGCCTACGCGTGGGCCTACAACGTCGAGAAGGGCAACAAGACCCGGATCATCGGCCCCA
ACTGCCCGGGCATCATCACCCCCGGCGAGTCGCTGGTCGGCATCACCCCGGCCAACATCACCGGCAAGGGCCCGATCGGC
CTGGTGTCCAAGTCGGGCACGCTGACCTACCAGATGATGTACGAGTTGCGCGATTTCGGCTTCTCGACCTCCATCGGCAT
CGGCGGCGACCCGGTCATCGGCACCACCCACATCGACGCCATCGAGGCGTTCGAGAAGGACCCCGAGACCAAGCTCATCG
TCATGATCGGCGAGATCGGCGGCGACGCCGAGGAGCGGGCCGCGGCCTACATCAAGGCCAACGTCACCAAGCCGGTGGTC
GGCTACGTCGCGGGCTTCACCGCGCCGGAGGGCAAGACCATGGGCCACGCGGGCGCCATCGTGTCGGGCTCCTCGGGCAC
CGCCCAGGCCAAGAAGGACGCGCTCGAGGCCGCGGGCGTCAAGGTCGGCAAGACGCCGTCCGAGACCGCCGCGCTCGCGC
GCGAGATCCTGGAGAAGGCGTCCATCACCGCCTGA

Upstream 100 bases:

>100_bases
CCCGCTGGTGACGCTGGCGCAGACAATGGACGAAGGCGCCGACAAGGCCGCCGAACTGGCAGCCGCCCGCTAACGACGGC
CGAGCAAGGGACCACACGAC

Downstream 100 bases:

>100_bases
TCCGACCAGCACGTGCCGAAGGCCGCCTTCCGATCGATACGGAAGGCGGCCTTCGTCTTCGGCGGGGCGGCGGCGCCGAT
CGCGGCCGAACGGTGCTGTT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTKIVGGVNARKAGTTVSHTDKDGNAVELPVFGTVAEAIKETGADVSIA
FVPPKFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNVEKGNKTRIIGPNCPGIITPGESLVGITPANITGKGPIG
LVSKSGTLTYQMMYELRDFGFSTSIGIGGDPVIGTTHIDAIEAFEKDPETKLIVMIGEIGGDAEERAAAYIKANVTKPVV
GYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKDALEAAGVKVGKTPSETAALAREILEKASITA

Sequences:

>Translated_304_residues
MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTKIVGGVNARKAGTTVSHTDKDGNAVELPVFGTVAEAIKETGADVSIA
FVPPKFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNVEKGNKTRIIGPNCPGIITPGESLVGITPANITGKGPIG
LVSKSGTLTYQMMYELRDFGFSTSIGIGGDPVIGTTHIDAIEAFEKDPETKLIVMIGEIGGDAEERAAAYIKANVTKPVV
GYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKDALEAAGVKVGKTPSETAALAREILEKASITA
>Mature_303_residues
SIFLNKDSKVIVQGITGGEGTKHTALMLKAGTKIVGGVNARKAGTTVSHTDKDGNAVELPVFGTVAEAIKETGADVSIAF
VPPKFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNVEKGNKTRIIGPNCPGIITPGESLVGITPANITGKGPIGL
VSKSGTLTYQMMYELRDFGFSTSIGIGGDPVIGTTHIDAIEAFEKDPETKLIVMIGEIGGDAEERAAAYIKANVTKPVVG
YVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKDALEAAGVKVGKTPSETAALAREILEKASITA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=306, Percent_Identity=47.3856209150327, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI38569421, Length=255, Percent_Identity=32.156862745098, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=32.156862745098, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1786949, Length=300, Percent_Identity=53.6666666666667, Blast_Score=297, Evalue=7e-82,
Organism=Caenorhabditis elegans, GI17550194, Length=293, Percent_Identity=51.877133105802, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17553126, Length=302, Percent_Identity=48.3443708609272, Blast_Score=243, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17557344, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=47.1186440677966, Blast_Score=228, Evalue=8e-61,
Organism=Drosophila melanogaster, GI21356559, Length=305, Percent_Identity=46.2295081967213, Blast_Score=248, Evalue=4e-66,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=48.122866894198, Blast_Score=220, Evalue=8e-58,
Organism=Drosophila melanogaster, GI281363477, Length=240, Percent_Identity=32.0833333333333, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281363475, Length=240, Percent_Identity=32.0833333333333, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281363473, Length=240, Percent_Identity=32.0833333333333, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31236; Mature: 31105

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTKIVGGVNARKAGTTVSHTDKDGNAVEL
CEEEEECCCEEEEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEECCCCCCEEEE
PVFGTVAEAIKETGADVSIAFVPPKFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAY
EEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEE
NVEKGNKTRIIGPNCPGIITPGESLVGITPANITGKGPIGLVSKSGTLTYQMMYELRDFG
EECCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEEHHHHHHHHCC
FSTSIGIGGDPVIGTTHIDAIEAFEKDPETKLIVMIGEIGGDAEERAAAYIKANVTKPVV
CEEECCCCCCCEEECCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHEEEEEEECCCCHHH
GYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKDALEAAGVKVGKTPSETAALAREILEKA
HHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHH
SITA
CCCC
>Mature Secondary Structure 
SIFLNKDSKVIVQGITGGEGTKHTALMLKAGTKIVGGVNARKAGTTVSHTDKDGNAVEL
EEEEECCCEEEEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEECCCCCCEEEE
PVFGTVAEAIKETGADVSIAFVPPKFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAY
EEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEE
NVEKGNKTRIIGPNCPGIITPGESLVGITPANITGKGPIGLVSKSGTLTYQMMYELRDFG
EECCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEEHHHHHHHHCC
FSTSIGIGGDPVIGTTHIDAIEAFEKDPETKLIVMIGEIGGDAEERAAAYIKANVTKPVV
CEEECCCCCCCEEECCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHEEEEEEECCCCHHH
GYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKDALEAAGVKVGKTPSETAALAREILEKA
HHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHH
SITA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]