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The map label for this gene is moaCB [H]

Identifier: 54026935

GI number: 54026935

Start: 5176999

End: 5177607

Strand: Reverse

Name: moaCB [H]

Synonym: nfa49610

Alternate gene names: 54026935

Gene position: 5177607-5176999 (Counterclockwise)

Preceding gene: 54026936

Following gene: 54026934

Centisome position: 85.99

GC content: 71.26

Gene sequence:

>609_bases
ATGATGCGCCCGACCCGGCTCGACCGGGTGCGGCTGATCTCGGTCGACGGCCTCGACCCGGAATTGTCCAGCGCTGCCGC
CGACTTGCTCGACGCAGGCGCTACGGTGAGCACTATGGATATCGATGCTCCTGTCGCGGGGCGCGCCCTGGTGGTGGTCG
TGGACGACCGGACCGCCCACGGTGGTGTGGACTCGCTCGGCCCGCTGGTCACCGAACTGCTCACCGAGGCGGGCTTCCTG
GTCGACGCGTCGGTGACCGTGCAGGCCGACGAGGTGGAGATCCGCAACGCGCTCAACACCGCGGTGATCGGCGGCGTCGA
TCTGGTGATCTCGGTCGGCGGCACCGGGATGTCGCCGCGCGATGTGACCCCCGAGGCGACGGCACAGGTGCTCGACCGCG
AACTGCCCGGCATCTCCGAGGCGCTGCGCTCCTCCGGCCGCGTCGCCGGTTCGCTCGACGCCGGGCTCTCCCGTGGCCTG
GCGGGCGTGTCCGGCTCGACCCTGGTGGTGAACCTGCCCGGTACCCGTGCCGCCATCCGGGACGGCATGGCCACCCTCTC
GCCGCTCGCCAGCAAGGTGATCGGCGAGCTGTCCGGTTTGGCGGAGTGA

Upstream 100 bases:

>100_bases
AACCAGGAGACAAGGTGAAGGTCACCTATACCGACGAGAACGGCAACAATCCGAAGACGGTCGAGGTCACCCTCACCGGC
GCGCCCGGGGACGGTGGCCG

Downstream 100 bases:

>100_bases
CTCCGCAGCCCGGCGATTCCGATACCCCTCGCCCGGCGGAGCGCCGGGCGAGGGACGCCGCGCGCCTGGCGCGGATCTTC
GGCGAGACCCTGCCCGACAC

Product: putative molybdopterin biosynthesis protein

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdenum cofactor biosynthesis protein B [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MMRPTRLDRVRLISVDGLDPELSSAAADLLDAGATVSTMDIDAPVAGRALVVVVDDRTAHGGVDSLGPLVTELLTEAGFL
VDASVTVQADEVEIRNALNTAVIGGVDLVISVGGTGMSPRDVTPEATAQVLDRELPGISEALRSSGRVAGSLDAGLSRGL
AGVSGSTLVVNLPGTRAAIRDGMATLSPLASKVIGELSGLAE

Sequences:

>Translated_202_residues
MMRPTRLDRVRLISVDGLDPELSSAAADLLDAGATVSTMDIDAPVAGRALVVVVDDRTAHGGVDSLGPLVTELLTEAGFL
VDASVTVQADEVEIRNALNTAVIGGVDLVISVGGTGMSPRDVTPEATAQVLDRELPGISEALRSSGRVAGSLDAGLSRGL
AGVSGSTLVVNLPGTRAAIRDGMATLSPLASKVIGELSGLAE
>Mature_202_residues
MMRPTRLDRVRLISVDGLDPELSSAAADLLDAGATVSTMDIDAPVAGRALVVVVDDRTAHGGVDSLGPLVTELLTEAGFL
VDASVTVQADEVEIRNALNTAVIGGVDLVISVGGTGMSPRDVTPEATAQVLDRELPGISEALRSSGRVAGSLDAGLSRGL
AGVSGSTLVVNLPGTRAAIRDGMATLSPLASKVIGELSGLAE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=87, Percent_Identity=40.2298850574713, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI66932975, Length=87, Percent_Identity=40.2298850574713, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=159, Percent_Identity=36.4779874213836, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17136978, Length=138, Percent_Identity=35.5072463768116, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24638841, Length=138, Percent_Identity=35.5072463768116, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR020817
- InterPro:   IPR012247
- InterPro:   IPR001453
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20391; Mature: 20391

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRPTRLDRVRLISVDGLDPELSSAAADLLDAGATVSTMDIDAPVAGRALVVVVDDRTAH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCC
GGVDSLGPLVTELLTEAGFLVDASVTVQADEVEIRNALNTAVIGGVDLVISVGGTGMSPR
CCCHHHHHHHHHHHHHCCEEEECEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
DVTPEATAQVLDRELPGISEALRSSGRVAGSLDAGLSRGLAGVSGSTLVVNLPGTRAAIR
CCCHHHHHHHHHHCCCCHHHHHHHCCCEEECHHHHHHHCCCCCCCCEEEEECCCCHHHHH
DGMATLSPLASKVIGELSGLAE
HCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRPTRLDRVRLISVDGLDPELSSAAADLLDAGATVSTMDIDAPVAGRALVVVVDDRTAH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCC
GGVDSLGPLVTELLTEAGFLVDASVTVQADEVEIRNALNTAVIGGVDLVISVGGTGMSPR
CCCHHHHHHHHHHHHHCCEEEECEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
DVTPEATAQVLDRELPGISEALRSSGRVAGSLDAGLSRGLAGVSGSTLVVNLPGTRAAIR
CCCHHHHHHHHHHCCCCHHHHHHHCCCEEECHHHHHHHCCCCCCCCEEEEECCCCHHHHH
DGMATLSPLASKVIGELSGLAE
HCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]