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The map label for this gene is degP [H]

Identifier: 54026936

GI number: 54026936

Start: 5177604

End: 5178851

Strand: Reverse

Name: degP [H]

Synonym: nfa49620

Alternate gene names: 54026936

Gene position: 5178851-5177604 (Counterclockwise)

Preceding gene: 54026937

Following gene: 54026935

Centisome position: 86.01

GC content: 71.23

Gene sequence:

>1248_bases
ATGACCGAGGATTTCCAGGCCGCGCCGCAGCACGCGAACCCGCAGCATCCGCACGGGCACTACCCGACCCAGCCGTTCTC
CGGACCGCATCCGGGCATGCCTGCCGCCACTCCGCCACCGCAGGCACCCGCGCGCCCGGCGCGGACCGGCCTGGTCGCCG
CCGCGGTGGCCCTTGCCCTGGTCAGCGGCGGCGTCGGCGGCGCGGTGGGCGCGGTGGTCACCCGTTCCGACGACGGCAGG
GCCCCGGTCACCAACGCGCTCGACGCGCCGAAACCCAGCGTCAGCAACGTCTCCAACGCCCCGGCCGGGTCCACCCAGGC
GGTCGCGCAGAAGGTGTTGCCGAGCGTGGTGATGATCAAGGTCGCCAGCAATCGCGCCGAGGGGGAGGGCTCCGGGGTGG
TGCTGTCCTCGGACGGACTGATCCTCACCAACAACCACGTGGCTTCCGGCGGCGGCACCGGCGCCCGCATGGAAGTCCAC
TTCGCCGATGGCTCCACCGCGCCCGCCACCGTCGTGGGCGCCGACCCGGTCTCGGACCTGGCGGTGATCAAGGCGCAGGG
CCGCACCGATCTCACCCCGATCGAGCTGGGTACCTCGGCGAGCCTGCAGGTCGGCCAGCCGGTCATCGCCATCGGCTCGC
CGCTCGGCCTGGCGGGCACGGTGACCACCGGTATCGTCTCCGCGCTCAATCGCCCGGTCTCCACCAGCGGTGAGGGCACC
CAGAATCCGAACGCTCCGCAGCCGGTGATCGACGCCATCCAGACCGACGCCGCCATCAATCCCGGCAATTCCGGTGGCGC
GCTGGTGGACTACGAGGGCAAACTGATCGGCATCAACACCGCCATCGCCACCCTCGGCGCGGGCGAACTCGGCGGCCAGC
AGAGCGGTTCGATCGGCCTGGGCTTCGCGATCCCGGTCGATCAGGCCCGCCGGGTGGCCGACGAGTTGATCAAGACCGGC
CAGGCCACCTACGCGCAGATCGGTATCAAGCTGCGCCCGCAGGACACCGCCGCGCTGGTGCTGGAAGCCACGCCGGGCGG
GCCCGCCGCGGCGGCGGGCATCCCGGCCGGCGCGATCATCACCAAACTCGACGACCGCGTCATCGATTCCGGCGAGGCAC
TCATCGCCGCCGTCCGATCCCATCAACCAGGAGACAAGGTGAAGGTCACCTATACCGACGAGAACGGCAACAATCCGAAG
ACGGTCGAGGTCACCCTCACCGGCGCGCCCGGGGACGGTGGCCGATGA

Upstream 100 bases:

>100_bases
GCCGGGCACTCACCTCTCGGAAAACTGAAAGCACGGTCTCAGTCCGCTCTAAGCCGACCCGGCCAGGCTCGACGGTGGAC
GTGAGGAGAAACGAGTAGTC

Downstream 100 bases:

>100_bases
TGCGCCCGACCCGGCTCGACCGGGTGCGGCTGATCTCGGTCGACGGCCTCGACCCGGAATTGTCCAGCGCTGCCGCCGAC
TTGCTCGACGCAGGCGCTAC

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTEDFQAAPQHANPQHPHGHYPTQPFSGPHPGMPAATPPPQAPARPARTGLVAAAVALALVSGGVGGAVGAVVTRSDDGR
APVTNALDAPKPSVSNVSNAPAGSTQAVAQKVLPSVVMIKVASNRAEGEGSGVVLSSDGLILTNNHVASGGGTGARMEVH
FADGSTAPATVVGADPVSDLAVIKAQGRTDLTPIELGTSASLQVGQPVIAIGSPLGLAGTVTTGIVSALNRPVSTSGEGT
QNPNAPQPVIDAIQTDAAINPGNSGGALVDYEGKLIGINTAIATLGAGELGGQQSGSIGLGFAIPVDQARRVADELIKTG
QATYAQIGIKLRPQDTAALVLEATPGGPAAAAGIPAGAIITKLDDRVIDSGEALIAAVRSHQPGDKVKVTYTDENGNNPK
TVEVTLTGAPGDGGR

Sequences:

>Translated_415_residues
MTEDFQAAPQHANPQHPHGHYPTQPFSGPHPGMPAATPPPQAPARPARTGLVAAAVALALVSGGVGGAVGAVVTRSDDGR
APVTNALDAPKPSVSNVSNAPAGSTQAVAQKVLPSVVMIKVASNRAEGEGSGVVLSSDGLILTNNHVASGGGTGARMEVH
FADGSTAPATVVGADPVSDLAVIKAQGRTDLTPIELGTSASLQVGQPVIAIGSPLGLAGTVTTGIVSALNRPVSTSGEGT
QNPNAPQPVIDAIQTDAAINPGNSGGALVDYEGKLIGINTAIATLGAGELGGQQSGSIGLGFAIPVDQARRVADELIKTG
QATYAQIGIKLRPQDTAALVLEATPGGPAAAAGIPAGAIITKLDDRVIDSGEALIAAVRSHQPGDKVKVTYTDENGNNPK
TVEVTLTGAPGDGGR
>Mature_414_residues
TEDFQAAPQHANPQHPHGHYPTQPFSGPHPGMPAATPPPQAPARPARTGLVAAAVALALVSGGVGGAVGAVVTRSDDGRA
PVTNALDAPKPSVSNVSNAPAGSTQAVAQKVLPSVVMIKVASNRAEGEGSGVVLSSDGLILTNNHVASGGGTGARMEVHF
ADGSTAPATVVGADPVSDLAVIKAQGRTDLTPIELGTSASLQVGQPVIAIGSPLGLAGTVTTGIVSALNRPVSTSGEGTQ
NPNAPQPVIDAIQTDAAINPGNSGGALVDYEGKLIGINTAIATLGAGELGGQQSGSIGLGFAIPVDQARRVADELIKTGQ
ATYAQIGIKLRPQDTAALVLEATPGGPAAAAGIPAGAIITKLDDRVIDSGEALIAAVRSHQPGDKVKVTYTDENGNNPKT
VEVTLTGAPGDGGR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=309, Percent_Identity=34.9514563106796, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4506141, Length=287, Percent_Identity=34.1463414634146, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7019477, Length=309, Percent_Identity=32.0388349514563, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI24308541, Length=216, Percent_Identity=36.5740740740741, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1789629, Length=345, Percent_Identity=37.1014492753623, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786356, Length=272, Percent_Identity=40.4411764705882, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789630, Length=295, Percent_Identity=33.5593220338983, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646839, Length=302, Percent_Identity=31.7880794701987, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41026; Mature: 40895

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDFQAAPQHANPQHPHGHYPTQPFSGPHPGMPAATPPPQAPARPARTGLVAAAVALAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VSGGVGGAVGAVVTRSDDGRAPVTNALDAPKPSVSNVSNAPAGSTQAVAQKVLPSVVMIK
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
VASNRAEGEGSGVVLSSDGLILTNNHVASGGGTGARMEVHFADGSTAPATVVGADPVSDL
EECCCCCCCCCEEEEECCCEEEECCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCE
AVIKAQGRTDLTPIELGTSASLQVGQPVIAIGSPLGLAGTVTTGIVSALNRPVSTSGEGT
EEEEECCCCCCCEEECCCCCCEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC
QNPNAPQPVIDAIQTDAAINPGNSGGALVDYEGKLIGINTAIATLGAGELGGQQSGSIGL
CCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEHHHHHCCCCCCCCCCCCCEEE
GFAIPVDQARRVADELIKTGQATYAQIGIKLRPQDTAALVLEATPGGPAAAAGIPAGAII
EEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHCCCCCCHHH
TKLDDRVIDSGEALIAAVRSHQPGDKVKVTYTDENGNNPKTVEVTLTGAPGDGGR
HHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TEDFQAAPQHANPQHPHGHYPTQPFSGPHPGMPAATPPPQAPARPARTGLVAAAVALAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VSGGVGGAVGAVVTRSDDGRAPVTNALDAPKPSVSNVSNAPAGSTQAVAQKVLPSVVMIK
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
VASNRAEGEGSGVVLSSDGLILTNNHVASGGGTGARMEVHFADGSTAPATVVGADPVSDL
EECCCCCCCCCEEEEECCCEEEECCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCE
AVIKAQGRTDLTPIELGTSASLQVGQPVIAIGSPLGLAGTVTTGIVSALNRPVSTSGEGT
EEEEECCCCCCCEEECCCCCCEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC
QNPNAPQPVIDAIQTDAAINPGNSGGALVDYEGKLIGINTAIATLGAGELGGQQSGSIGL
CCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEHHHHHCCCCCCCCCCCCCEEE
GFAIPVDQARRVADELIKTGQATYAQIGIKLRPQDTAALVLEATPGGPAAAAGIPAGAII
EEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHCCCCCCHHH
TKLDDRVIDSGEALIAAVRSHQPGDKVKVTYTDENGNNPKTVEVTLTGAPGDGGR
HHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]