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The map label for this gene is hemK [C]

Identifier: 54026829

GI number: 54026829

Start: 5067934

End: 5068590

Strand: Reverse

Name: hemK [C]

Synonym: nfa48550

Alternate gene names: 54026829

Gene position: 5068590-5067934 (Counterclockwise)

Preceding gene: 54026830

Following gene: 54026828

Centisome position: 84.18

GC content: 75.04

Gene sequence:

>657_bases
GTGCGACTCCTCCGAGCCCCGGGCGTCTACCGTCCGCAAACCGACACCCGGCTGCTGGCCGAGGCGGCCACCGCGGCCAC
CCTGCCGCAGCGGCCGCGCGTCCTCGACCCGTGCACCGGGACCGGGGCGCTGGCCATCGCCGCCGCCGAAGCGGGCGCCG
AGTCCGTCACCGCGGTCGACCTGTCCCGCCGCGCCGTCGCCACCGCCTGGTTGAACAGCCGCCTGCGCGGGCTCCACATC
GAACTGCTGCGCGGTGATTTCGCGGCCGTGCTGGGGGAGCGGACCTTCGATGTGGTGCTGGCCAACCCGCCGTACGTGCC
GTGCGCGGACCCGCACCCCGCCCGCGGCGCCGACCGCGCCTGGGACGCCGGCCACGACGGCCGCGCGGTGCTGGACCGGC
TCTGTGACCAGCTGCCGCGGCTGCTCGCCCCGCGTGGCGTCGCGTTGATCGTGCACTCCGAGCTGTGCGGCGAGGAGACG
TCGCTGCGGCGGCTGCGCGACAACGGCTTGAAGGCCTCCACCGTCGCCCGCCACATCATCCCGTTCGGGCCGGTGCTGCG
CGAGCGCGCCGCCTGGCTCGAATCGGTCGGGCTGATCGCGCCCGGCCAACGTCACGAGGAACTGGTGGTCATCCGTGCCG
ACCGCATCGAACGCTGA

Upstream 100 bases:

>100_bases
GAGCACGACATCCTCGACGGCATCGCCCTGTCCATCGCCTGATCCGCCGCCGGAACGCCGGCGTTCGTTTCGGTCGAGAT
GATCGAGGTATTCCCGCCTC

Downstream 100 bases:

>100_bases
CGCACACACCGAAAACGACCGTGCCGGGACCGGATCGGTGACGGACCGCCGGGTGGTCCGCGCGGAACCGGAGCGGCGGC
GCATCACCTACACCGACGAC

Product: putative methyltransferase

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRLLRAPGVYRPQTDTRLLAEAATAATLPQRPRVLDPCTGTGALAIAAAEAGAESVTAVDLSRRAVATAWLNSRLRGLHI
ELLRGDFAAVLGERTFDVVLANPPYVPCADPHPARGADRAWDAGHDGRAVLDRLCDQLPRLLAPRGVALIVHSELCGEET
SLRRLRDNGLKASTVARHIIPFGPVLRERAAWLESVGLIAPGQRHEELVVIRADRIER

Sequences:

>Translated_218_residues
MRLLRAPGVYRPQTDTRLLAEAATAATLPQRPRVLDPCTGTGALAIAAAEAGAESVTAVDLSRRAVATAWLNSRLRGLHI
ELLRGDFAAVLGERTFDVVLANPPYVPCADPHPARGADRAWDAGHDGRAVLDRLCDQLPRLLAPRGVALIVHSELCGEET
SLRRLRDNGLKASTVARHIIPFGPVLRERAAWLESVGLIAPGQRHEELVVIRADRIER
>Mature_218_residues
MRLLRAPGVYRPQTDTRLLAEAATAATLPQRPRVLDPCTGTGALAIAAAEAGAESVTAVDLSRRAVATAWLNSRLRGLHI
ELLRGDFAAVLGERTFDVVLANPPYVPCADPHPARGADRAWDAGHDGRAVLDRLCDQLPRLLAPRGVALIVHSELCGEET
SLRRLRDNGLKASTVARHIIPFGPVLRERAAWLESVGLIAPGQRHEELVVIRADRIER

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Escherichia coli, GI1787463, Length=166, Percent_Identity=34.3373493975904, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204212, Length=213, Percent_Identity=30.5164319248826, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 23622; Mature: 23622

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLRAPGVYRPQTDTRLLAEAATAATLPQRPRVLDPCTGTGALAIAAAEAGAESVTAVD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEHHH
LSRRAVATAWLNSRLRGLHIELLRGDFAAVLGERTFDVVLANPPYVPCADPHPARGADRA
HHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCC
WDAGHDGRAVLDRLCDQLPRLLAPRGVALIVHSELCGEETSLRRLRDNGLKASTVARHII
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHCCCHHHHHHHHHCCCCHHHHHHHHC
PFGPVLRERAAWLESVGLIAPGQRHEELVVIRADRIER
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRLLRAPGVYRPQTDTRLLAEAATAATLPQRPRVLDPCTGTGALAIAAAEAGAESVTAVD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEHHH
LSRRAVATAWLNSRLRGLHIELLRGDFAAVLGERTFDVVLANPPYVPCADPHPARGADRA
HHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCC
WDAGHDGRAVLDRLCDQLPRLLAPRGVALIVHSELCGEETSLRRLRDNGLKASTVARHII
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHCCCHHHHHHHHHCCCCHHHHHHHHC
PFGPVLRERAAWLESVGLIAPGQRHEELVVIRADRIER
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]