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The map label for this gene is gppA [H]

Identifier: 54026830

GI number: 54026830

Start: 5068649

End: 5069596

Strand: Reverse

Name: gppA [H]

Synonym: nfa48560

Alternate gene names: 54026830

Gene position: 5069596-5068649 (Counterclockwise)

Preceding gene: 54026831

Following gene: 54026829

Centisome position: 84.2

GC content: 72.47

Gene sequence:

>948_bases
ATGAGTGATCGGATCGCCGCGGTCGACTGCGGCACCAACTCCATCCGGTTGCTGATCGCCGACGTGCGATCCGACGGACG
GCTGGCCGACGTACACCGCGAGATGCGGATCGTGCGCCTGGGCCAGGGCGTCGACGCCACCGGCGCGCTGCACCCCGACG
CCATCGAACGCACCAGGGCGGCGCTGGCCGACTACGTCGACATCATGCGCGAGACGGGTGTCGCGCGGGTCCGCATGGTC
GCCACCTCCGCGACCCGCGACGCCGCCAACCGCGCCGACTTCTTCGCGATGGCGCGCGCCGAACTGGGCCGGGCGGTCCC
CGGCGCCGAAGCCGAGGTCATCAGCGGTGACGAGGAAGCCCGCCTGTCGTTCACCGGCGCGGTGGGCGAGCTGAGCGGCA
GCGCCGGGCCGTTCGTCGTGGTCGATCTCGGCGGCGGTTCGACCGAGCTGGTCTTCGGTGACGCGAACGGCGTCGAGGCC
GCGTTCTCCGCCGACATCGGCTGCGTGCGGATCACCGAACGTTGCCTGCACGACGACCCGCCCACCCGAGAGCAGATCGC
CGAAGCCAGGCAGTTCGCCGCCGAGCGACTCGCCGAGGCGTTCGTTCGCGTCCCGGTCAGCCGCGCGCACACCTGGGTCG
GGGTCGCGGGCACCATGACCACGCTGGCCGCGGTCGCGCTCGACCTGCCCGAGTACGACCCCGCCCGCATCCACCTCACC
GCGCTGCCGCTGGACCGGGTGCGCGCCGCCTGCGACCGGCTCATCGCGATGACCCACGACGAACGCGCCGCGCTGGGGCC
CATGCATCCGGGCCGGGTGGACGTGATCGGCGGCGGCGCGGTGATCACCGAGCTGCTCGCCGAGGAACTGTCCCGCCGGG
CGGGCATCACCGAACTGATCGTCAGCGAGCACGACATCCTCGACGGCATCGCCCTGTCCATCGCCTGA

Upstream 100 bases:

>100_bases
CTCGGTGACGAGGCCGTCGCGCTGGCCGCCGAGCACGGGTTGCGCGGCACCGTCGTTCCGGCCGACTGGCCGACCTACGA
GCCGAAAGGCGGAGCAGCAC

Downstream 100 bases:

>100_bases
TCCGCCGCCGGAACGCCGGCGTTCGTTTCGGTCGAGATGATCGAGGTATTCCCGCCTCGTGCGACTCCTCCGAGCCCCGG
GCGTCTACCGTCCGCAAACC

Product: putative exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSDRIAAVDCGTNSIRLLIADVRSDGRLADVHREMRIVRLGQGVDATGALHPDAIERTRAALADYVDIMRETGVARVRMV
ATSATRDAANRADFFAMARAELGRAVPGAEAEVISGDEEARLSFTGAVGELSGSAGPFVVVDLGGGSTELVFGDANGVEA
AFSADIGCVRITERCLHDDPPTREQIAEARQFAAERLAEAFVRVPVSRAHTWVGVAGTMTTLAAVALDLPEYDPARIHLT
ALPLDRVRAACDRLIAMTHDERAALGPMHPGRVDVIGGGAVITELLAEELSRRAGITELIVSEHDILDGIALSIA

Sequences:

>Translated_315_residues
MSDRIAAVDCGTNSIRLLIADVRSDGRLADVHREMRIVRLGQGVDATGALHPDAIERTRAALADYVDIMRETGVARVRMV
ATSATRDAANRADFFAMARAELGRAVPGAEAEVISGDEEARLSFTGAVGELSGSAGPFVVVDLGGGSTELVFGDANGVEA
AFSADIGCVRITERCLHDDPPTREQIAEARQFAAERLAEAFVRVPVSRAHTWVGVAGTMTTLAAVALDLPEYDPARIHLT
ALPLDRVRAACDRLIAMTHDERAALGPMHPGRVDVIGGGAVITELLAEELSRRAGITELIVSEHDILDGIALSIA
>Mature_314_residues
SDRIAAVDCGTNSIRLLIADVRSDGRLADVHREMRIVRLGQGVDATGALHPDAIERTRAALADYVDIMRETGVARVRMVA
TSATRDAANRADFFAMARAELGRAVPGAEAEVISGDEEARLSFTGAVGELSGSAGPFVVVDLGGGSTELVFGDANGVEAA
FSADIGCVRITERCLHDDPPTREQIAEARQFAAERLAEAFVRVPVSRAHTWVGVAGTMTTLAAVALDLPEYDPARIHLTA
LPLDRVRAACDRLIAMTHDERAALGPMHPGRVDVIGGGAVITELLAEELSRRAGITELIVSEHDILDGIALSIA

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=278, Percent_Identity=35.6115107913669, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788848, Length=229, Percent_Identity=31.8777292576419, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33320; Mature: 33189

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRIAAVDCGTNSIRLLIADVRSDGRLADVHREMRIVRLGQGVDATGALHPDAIERTRA
CCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHH
ALADYVDIMRETGVARVRMVATSATRDAANRADFFAMARAELGRAVPGAEAEVISGDEEA
HHHHHHHHHHHCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
RLSFTGAVGELSGSAGPFVVVDLGGGSTELVFGDANGVEAAFSADIGCVRITERCLHDDP
EEEEECCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHCCCC
PTREQIAEARQFAAERLAEAFVRVPVSRAHTWVGVAGTMTTLAAVALDLPEYDPARIHLT
CCHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEE
ALPLDRVRAACDRLIAMTHDERAALGPMHPGRVDVIGGGAVITELLAEELSRRAGITELI
ECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHH
VSEHDILDGIALSIA
HHHHHHHHCEEEECC
>Mature Secondary Structure 
SDRIAAVDCGTNSIRLLIADVRSDGRLADVHREMRIVRLGQGVDATGALHPDAIERTRA
CCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHH
ALADYVDIMRETGVARVRMVATSATRDAANRADFFAMARAELGRAVPGAEAEVISGDEEA
HHHHHHHHHHHCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
RLSFTGAVGELSGSAGPFVVVDLGGGSTELVFGDANGVEAAFSADIGCVRITERCLHDDP
EEEEECCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHCCCC
PTREQIAEARQFAAERLAEAFVRVPVSRAHTWVGVAGTMTTLAAVALDLPEYDPARIHLT
CCHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEE
ALPLDRVRAACDRLIAMTHDERAALGPMHPGRVDVIGGGAVITELLAEELSRRAGITELI
ECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHH
VSEHDILDGIALSIA
HHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]