Click here to switch to the map view.

The map label for this gene is rlmG [H]

Identifier: 54026812

GI number: 54026812

Start: 5052597

End: 5053748

Strand: Reverse

Name: rlmG [H]

Synonym: nfa48380

Alternate gene names: 54026812

Gene position: 5053748-5052597 (Counterclockwise)

Preceding gene: 54026815

Following gene: 54026811

Centisome position: 83.93

GC content: 72.22

Gene sequence:

>1152_bases
GTGCACGATGTGGAGGACGTACTCCGTCGCCTGCGGCGGTATCCGGACGTGGAGGCGGTCAACCTCTATGCCGTCGACGC
CGCCGACCGGCTGATCCTCGACGTGGCCGCCGACGCCATCGAGGCAGCGGGCAGCGGGCGTGTCGCGGTGATCGGCGACA
GCTACGGCGCGCTCACGCTCGGCGCGATCGCCCGCCACGACCTGCGCGAGGTGCGCGTGCACCAGGACCTGCTCACCGGT
GAGCTGGCCCTGGCCAACAACGCGCGCGCGGTGGGCCTGACCGACCGCTACGTGCCCCAGCCGCTCACCGAGGCACTGCT
CGCCGACGCGACCGTGGTGCTGCTGCGGCTGCCCCGGGCGCTGGCCGGACTGTCCGAGGTGGCCGACGCCATCGCCCGGT
ACGCCGACCCCGCCGTGCAGGTGATCGCCGGTGGCCGGGACAAGTACCTGACCAAGACCATGAACGACGTGCTCGGCGAG
TCGTTCGCCGAGGTCAGGGCCAGCCGGGGCAGGCAGAAGTCGCGGACGCTGCTGGCCTCGGGACCCAAACCGGTGGGGGC
GCCGCCGTTCCCGGTCCGGGAGCGGCTCGACGAGATCGATCTGGAGGTGGTCGCGCACGGCGCGGCCTTCTCCGGTCCGC
GACTCGACATCGGCACCCGCTTCCTGCTCGAACATCTCAAGCTGATGAAGCCCGACGCCCGCGATGCCATCGATCTGGGC
TGCGGCACCGGCATCCTCGCGGTCGCGCTGGCGAAGGCACGGCCGGGCCTGCGCGTGGTCGGCACCGACCAGTCCGCCGC
CGCGGTCGCCTCCGCGGAGGCGACCGCCGCCGCCAACGCCGTCGCCGACCGGGTGCGGGTGGTCCGGGACGACGCGATGT
CCTCGGCCCCGGACAACAGCGCCGATCTGGTGCTGTGCAACCCGCCCTTCCACGTCGGCGCGGCGGTGCACACCGGGGCC
GCGATCAAGATGTTCGCCGAGACGGGTCGCGTTCTGCGGCCGGGTGGGGAATTGTGGACGGTGTACAACTCACACCTCGA
CTACCGGGGTGTGGTGGAGCGGATGGTCGGCCGGACCGACGTGGTCGGGCGCAACCGGAAGTTCACGGTGACTCGGTCGG
TGCGTGGGCTGCACGACGTCCGGCAACGGTAG

Upstream 100 bases:

>100_bases
GCCACCAGCACTGCCAGTCTGTTGCGCATGAGGCTGATGTTAATCGCCCGCGGCGGGGGTGGTCGTGATCGCCGTGGCAA
CGATCTAGCACACTTGAGCC

Downstream 100 bases:

>100_bases
AGTCCGAAATGTCCGCCTCGTGGTTCCTGTGGGAACTCGGCGGCGGAGCCGCACGTTGAACAGAACAAGTTGGAGCTCGA
GCGCCAGCTCGATCAGACAG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmG [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MHDVEDVLRRLRRYPDVEAVNLYAVDAADRLILDVAADAIEAAGSGRVAVIGDSYGALTLGAIARHDLREVRVHQDLLTG
ELALANNARAVGLTDRYVPQPLTEALLADATVVLLRLPRALAGLSEVADAIARYADPAVQVIAGGRDKYLTKTMNDVLGE
SFAEVRASRGRQKSRTLLASGPKPVGAPPFPVRERLDEIDLEVVAHGAAFSGPRLDIGTRFLLEHLKLMKPDARDAIDLG
CGTGILAVALAKARPGLRVVGTDQSAAAVASAEATAAANAVADRVRVVRDDAMSSAPDNSADLVLCNPPFHVGAAVHTGA
AIKMFAETGRVLRPGGELWTVYNSHLDYRGVVERMVGRTDVVGRNRKFTVTRSVRGLHDVRQR

Sequences:

>Translated_383_residues
MHDVEDVLRRLRRYPDVEAVNLYAVDAADRLILDVAADAIEAAGSGRVAVIGDSYGALTLGAIARHDLREVRVHQDLLTG
ELALANNARAVGLTDRYVPQPLTEALLADATVVLLRLPRALAGLSEVADAIARYADPAVQVIAGGRDKYLTKTMNDVLGE
SFAEVRASRGRQKSRTLLASGPKPVGAPPFPVRERLDEIDLEVVAHGAAFSGPRLDIGTRFLLEHLKLMKPDARDAIDLG
CGTGILAVALAKARPGLRVVGTDQSAAAVASAEATAAANAVADRVRVVRDDAMSSAPDNSADLVLCNPPFHVGAAVHTGA
AIKMFAETGRVLRPGGELWTVYNSHLDYRGVVERMVGRTDVVGRNRKFTVTRSVRGLHDVRQR
>Mature_383_residues
MHDVEDVLRRLRRYPDVEAVNLYAVDAADRLILDVAADAIEAAGSGRVAVIGDSYGALTLGAIARHDLREVRVHQDLLTG
ELALANNARAVGLTDRYVPQPLTEALLADATVVLLRLPRALAGLSEVADAIARYADPAVQVIAGGRDKYLTKTMNDVLGE
SFAEVRASRGRQKSRTLLASGPKPVGAPPFPVRERLDEIDLEVVAHGAAFSGPRLDIGTRFLLEHLKLMKPDARDAIDLG
CGTGILAVALAKARPGLRVVGTDQSAAAVASAEATAAANAVADRVRVVRDDAMSSAPDNSADLVLCNPPFHVGAAVHTGA
AIKMFAETGRVLRPGGELWTVYNSHLDYRGVVERMVGRTDVVGRNRKFTVTRSVRGLHDVRQR

Specific function: Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmG family [H]

Homologues:

Organism=Escherichia coli, GI87082206, Length=379, Percent_Identity=29.287598944591, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1790830, Length=166, Percent_Identity=34.9397590361446, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR017237
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.174 [H]

Molecular weight: Translated: 40897; Mature: 40897

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDVEDVLRRLRRYPDVEAVNLYAVDAADRLILDVAADAIEAAGSGRVAVIGDSYGALTL
CCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
GAIARHDLREVRVHQDLLTGELALANNARAVGLTDRYVPQPLTEALLADATVVLLRLPRA
HHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAGLSEVADAIARYADPAVQVIAGGRDKYLTKTMNDVLGESFAEVRASRGRQKSRTLLAS
HHHHHHHHHHHHHHCCCHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEC
GPKPVGAPPFPVRERLDEIDLEVVAHGAAFSGPRLDIGTRFLLEHLKLMKPDARDAIDLG
CCCCCCCCCCCHHHHHHHCCHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCC
CGTGILAVALAKARPGLRVVGTDQSAAAVASAEATAAANAVADRVRVVRDDAMSSAPDNS
CCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ADLVLCNPPFHVGAAVHTGAAIKMFAETGRVLRPGGELWTVYNSHLDYRGVVERMVGRTD
CCEEEECCCCCCCHHHHCCHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHHCCCCC
VVGRNRKFTVTRSVRGLHDVRQR
CCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MHDVEDVLRRLRRYPDVEAVNLYAVDAADRLILDVAADAIEAAGSGRVAVIGDSYGALTL
CCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
GAIARHDLREVRVHQDLLTGELALANNARAVGLTDRYVPQPLTEALLADATVVLLRLPRA
HHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAGLSEVADAIARYADPAVQVIAGGRDKYLTKTMNDVLGESFAEVRASRGRQKSRTLLAS
HHHHHHHHHHHHHHCCCHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEC
GPKPVGAPPFPVRERLDEIDLEVVAHGAAFSGPRLDIGTRFLLEHLKLMKPDARDAIDLG
CCCCCCCCCCCHHHHHHHCCHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCC
CGTGILAVALAKARPGLRVVGTDQSAAAVASAEATAAANAVADRVRVVRDDAMSSAPDNS
CCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ADLVLCNPPFHVGAAVHTGAAIKMFAETGRVLRPGGELWTVYNSHLDYRGVVERMVGRTD
CCEEEECCCCCCCHHHHCCHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHHCCCCC
VVGRNRKFTVTRSVRGLHDVRQR
CCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA