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The map label for this gene is typA [H]

Identifier: 54026733

GI number: 54026733

Start: 4971278

End: 4973176

Strand: Reverse

Name: typA [H]

Synonym: nfa47590

Alternate gene names: 54026733

Gene position: 4973176-4971278 (Counterclockwise)

Preceding gene: 54026736

Following gene: 54026732

Centisome position: 82.59

GC content: 70.3

Gene sequence:

>1899_bases
GTGTCGTCTGCACGCGATTTTCGCAACGTCGCCATCGTGGCGCACGTCGACCACGGTAAGACGACACTTGTCGACGCCAT
GCTCCGCCAGTCCGGCGCCTTCGCCGAACGCGCCGAACCCGTCGACCGGGTGATGGACTCCGGTGATCTCGAGCGCGAGA
AGGGCATCACCATTCTCGCCAAGAACACCGCGGTGCACCGGCACCACCCGGACGGCTCGGTCACCGTCATCAACGTCATC
GACACCCCGGGGCACGCCGATTTCGGCGGCGAGGTCGAGCGCGGCCTGTCCATGGTCGACGGCGTCGTGCTGCTCGTGGA
CGCCTCCGAGGGGCCGCTGCCGCAGACCCGCTTCGTGCTGCGCAAGGCGCTGGCCGCCTCGCTGCCGGTGATCCTGGTGG
TCAACAAGACCGACCGCCCCGACGCCCGCATCGCCGAGGTCGTCGAGGAGAGCCACGATCTGCTGCTCGACCTGGCCTCC
GACCTCGACGACGAGGCCGCCGAAGCCGCCGAGCTGGCCCTGGACCTACCGGTCCTCTACGCCTCCGGCCGCGAGGGCAA
GGCCTCCACCGAGCGCCCCGAGAACGGCAACGCCCCCGACGCCCCGAACCTGGACGCGCTGTTCGACGTGCTGCTGAAGC
ACGTGCCCGCGCCCAAGGGCGACGCGCAGGCGCCGCTGCAGGCCCATGTCACCAACCTCGACGCCTCGCCGTTCCTGGGC
AGGCTGGCGCTGGTCCGCATCCACAACGGCACCCTGAAGAAGGGGCAGAACGTGGCGTGGATGAGTGCCGAGGGCACCAA
GACGGTGAAGATCACCGAGCTGCTCGCCACCGTCGGCGTGGAGCGCAACCCGGCGGAGGAAGCCGAGGCCGGCGACATCG
TCGCCGTGGCGGGCATCCCGGACATCATGATCGGCGACACCCTCGCCGACCCGGACAACCCGGTCGCGCTGCCCCGCATC
ACCGTCGACGAGCCCGCCATCTCGGTGACCATCGGCATCAACACCTCGCCGCTGGCCGGCCGCAACGGCGGCACCAAGCT
CACCGCCCGGCTGCTCAAGGCGCGCCTGGACCAGGAGCTGGTCGGCAACGTCTCGCTGCGGGTGCTCAACACCGACCGCC
CCGACACCTGGGAGGTGCAGGGCCGCGGTGAGCTGGCGCTGGCGATCCTGGTGGAGACCATGCGCCGGGAAGGCTTCGAG
CTCACCGTCGGCAAGCCACAGGTGGTCACCCGGATGGTCGACGGCAAGGTGCACGAGCCGTTCGAGGAACTGACCATCGA
CGTGCCCGAGGAGCACCTGGGCGCGGTCACCCAGCTGCTGGCCGCCCGCAAGGGCAAGATGGTGCAGATGACCAACCAGG
GTCACGGCTGGGTGCGGATGGAGTTCATCGTGCCCTCGCGCGGCCTGATCGGCTTCCGCACCGACTTCCTCACCGAGACC
CGCGGCACCGGCATCGCCAACGCCGTCGCGCACGGCTACGCGCCGTGGGCGGGCGAGATCCGCTCCCGGCACACCGGCTC
GCTGGTGTCCGACCGCGCGGGCAGCGTCACCGCCTACGCGATGTTGCAGCTGGCCGACCGCGGCACCTTCTTCGTGGAGC
CGGGCGCGGAGACCTACGAGGGCATGGTCGTCGGCATCAATCCGCGCGCGGAAGACCTCGACATCAACGTCACCCGCGAG
AAGAAGCTGACCAACATGCGCTCCTCCACCGGCGACGTGCTCGAGACCCTGGCGCGGCCGCTGGTGCTGGATCTGGAAGG
CGCGCTGGAGTTCTGCGCGGCCGACGAGTGCGTCGAGGTCGGCCCCGACGTGGTGCGGGTGCGCAAGGTCATCCTCAACG
CCAACGAGCGCGCCCGCGAGCTGTCGCGGCGGAAGGCACGGGACCGGGCCGCGTTGTAG

Upstream 100 bases:

>100_bases
CGGTAGTGTGTGCGATGGCCGCGATGCCCGGTGAGTTTCCATTCTCCACCTGTTTGCAGGGGTCGGCCGGCACCAATACC
TATCAGCAGGAGGATCCAGC

Downstream 100 bases:

>100_bases
AGTGCGGGACGTGAATTCGGGGGCGAGACGACGCGCGATGCTGCGCGTGCTGCAGATCCTGCTGGCGGCCTCCGTCCTGG
TGGTGGCCGGATGCACCGCG

Product: putative GTP-binding elongation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSSARDFRNVAIVAHVDHGKTTLVDAMLRQSGAFAERAEPVDRVMDSGDLEREKGITILAKNTAVHRHHPDGSVTVINVI
DTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALAASLPVILVVNKTDRPDARIAEVVEESHDLLLDLAS
DLDDEAAEAAELALDLPVLYASGREGKASTERPENGNAPDAPNLDALFDVLLKHVPAPKGDAQAPLQAHVTNLDASPFLG
RLALVRIHNGTLKKGQNVAWMSAEGTKTVKITELLATVGVERNPAEEAEAGDIVAVAGIPDIMIGDTLADPDNPVALPRI
TVDEPAISVTIGINTSPLAGRNGGTKLTARLLKARLDQELVGNVSLRVLNTDRPDTWEVQGRGELALAILVETMRREGFE
LTVGKPQVVTRMVDGKVHEPFEELTIDVPEEHLGAVTQLLAARKGKMVQMTNQGHGWVRMEFIVPSRGLIGFRTDFLTET
RGTGIANAVAHGYAPWAGEIRSRHTGSLVSDRAGSVTAYAMLQLADRGTFFVEPGAETYEGMVVGINPRAEDLDINVTRE
KKLTNMRSSTGDVLETLARPLVLDLEGALEFCAADECVEVGPDVVRVRKVILNANERARELSRRKARDRAAL

Sequences:

>Translated_632_residues
MSSARDFRNVAIVAHVDHGKTTLVDAMLRQSGAFAERAEPVDRVMDSGDLEREKGITILAKNTAVHRHHPDGSVTVINVI
DTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALAASLPVILVVNKTDRPDARIAEVVEESHDLLLDLAS
DLDDEAAEAAELALDLPVLYASGREGKASTERPENGNAPDAPNLDALFDVLLKHVPAPKGDAQAPLQAHVTNLDASPFLG
RLALVRIHNGTLKKGQNVAWMSAEGTKTVKITELLATVGVERNPAEEAEAGDIVAVAGIPDIMIGDTLADPDNPVALPRI
TVDEPAISVTIGINTSPLAGRNGGTKLTARLLKARLDQELVGNVSLRVLNTDRPDTWEVQGRGELALAILVETMRREGFE
LTVGKPQVVTRMVDGKVHEPFEELTIDVPEEHLGAVTQLLAARKGKMVQMTNQGHGWVRMEFIVPSRGLIGFRTDFLTET
RGTGIANAVAHGYAPWAGEIRSRHTGSLVSDRAGSVTAYAMLQLADRGTFFVEPGAETYEGMVVGINPRAEDLDINVTRE
KKLTNMRSSTGDVLETLARPLVLDLEGALEFCAADECVEVGPDVVRVRKVILNANERARELSRRKARDRAAL
>Mature_631_residues
SSARDFRNVAIVAHVDHGKTTLVDAMLRQSGAFAERAEPVDRVMDSGDLEREKGITILAKNTAVHRHHPDGSVTVINVID
TPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALAASLPVILVVNKTDRPDARIAEVVEESHDLLLDLASD
LDDEAAEAAELALDLPVLYASGREGKASTERPENGNAPDAPNLDALFDVLLKHVPAPKGDAQAPLQAHVTNLDASPFLGR
LALVRIHNGTLKKGQNVAWMSAEGTKTVKITELLATVGVERNPAEEAEAGDIVAVAGIPDIMIGDTLADPDNPVALPRIT
VDEPAISVTIGINTSPLAGRNGGTKLTARLLKARLDQELVGNVSLRVLNTDRPDTWEVQGRGELALAILVETMRREGFEL
TVGKPQVVTRMVDGKVHEPFEELTIDVPEEHLGAVTQLLAARKGKMVQMTNQGHGWVRMEFIVPSRGLIGFRTDFLTETR
GTGIANAVAHGYAPWAGEIRSRHTGSLVSDRAGSVTAYAMLQLADRGTFFVEPGAETYEGMVVGINPRAEDLDINVTREK
KLTNMRSSTGDVLETLARPLVLDLEGALEFCAADECVEVGPDVVRVRKVILNANERARELSRRKARDRAAL

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=541, Percent_Identity=26.9870609981516, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI94966754, Length=159, Percent_Identity=37.7358490566038, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI4503483, Length=152, Percent_Identity=36.8421052631579, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI18390331, Length=148, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI217272894, Length=144, Percent_Identity=36.8055555555556, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI217272892, Length=144, Percent_Identity=36.8055555555556, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310132016, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310110807, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310123363, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI34147630, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI25306283, Length=181, Percent_Identity=35.3591160220994, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI19923640, Length=182, Percent_Identity=35.1648351648352, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI25306287, Length=182, Percent_Identity=35.1648351648352, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI94966752, Length=112, Percent_Identity=36.6071428571429, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI53729339, Length=248, Percent_Identity=29.4354838709677, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI53729337, Length=248, Percent_Identity=29.4354838709677, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI48994988, Length=615, Percent_Identity=46.6666666666667, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI1789738, Length=504, Percent_Identity=29.1666666666667, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1788922, Length=531, Percent_Identity=28.4369114877589, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1789737, Length=316, Percent_Identity=27.5316455696203, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790412, Length=316, Percent_Identity=27.5316455696203, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790835, Length=138, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=276, Percent_Identity=31.5217391304348, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17556745, Length=349, Percent_Identity=27.5071633237822, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=136, Percent_Identity=38.9705882352941, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=136, Percent_Identity=38.9705882352941, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=140, Percent_Identity=35.7142857142857, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=140, Percent_Identity=42.8571428571429, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=306, Percent_Identity=28.4313725490196, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323320, Length=532, Percent_Identity=25.5639097744361, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323098, Length=504, Percent_Identity=27.5793650793651, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324707, Length=152, Percent_Identity=37.5, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=152, Percent_Identity=37.5, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324166, Length=141, Percent_Identity=39.7163120567376, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322359, Length=156, Percent_Identity=36.5384615384615, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324761, Length=295, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706572, Length=532, Percent_Identity=27.8195488721804, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24585709, Length=156, Percent_Identity=37.8205128205128, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585711, Length=156, Percent_Identity=37.8205128205128, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585713, Length=156, Percent_Identity=37.8205128205128, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=39.568345323741, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24582462, Length=242, Percent_Identity=32.6446280991736, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357743, Length=133, Percent_Identity=36.8421052631579, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19921738, Length=289, Percent_Identity=27.681660899654, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363316, Length=353, Percent_Identity=27.4787535410765, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17864358, Length=353, Percent_Identity=27.4787535410765, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221458488, Length=157, Percent_Identity=42.0382165605096, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28572034, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68043; Mature: 67912

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSARDFRNVAIVAHVDHGKTTLVDAMLRQSGAFAERAEPVDRVMDSGDLEREKGITILA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHCCHHHHHHCCCCCHHHCCCEEEE
KNTAVHRHHPDGSVTVINVIDTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVL
ECCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
RKALAASLPVILVVNKTDRPDARIAEVVEESHDLLLDLASDLDDEAAEAAELALDLPVLY
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEE
ASGREGKASTERPENGNAPDAPNLDALFDVLLKHVPAPKGDAQAPLQAHVTNLDASPFLG
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCC
RLALVRIHNGTLKKGQNVAWMSAEGTKTVKITELLATVGVERNPAEEAEAGDIVAVAGIP
EEEEEEEECCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
DIMIGDTLADPDNPVALPRITVDEPAISVTIGINTSPLAGRNGGTKLTARLLKARLDQEL
CEEECCCCCCCCCCEECCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHH
VGNVSLRVLNTDRPDTWEVQGRGELALAILVETMRREGFELTVGKPQVVTRMVDGKVHEP
HCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCCCC
FEELTIDVPEEHLGAVTQLLAARKGKMVQMTNQGHGWVRMEFIVPSRGLIGFRTDFLTET
HHHCEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEEEHHHHHHC
RGTGIANAVAHGYAPWAGEIRSRHTGSLVSDRAGSVTAYAMLQLADRGTFFVEPGAETYE
CCCCHHHHHHCCCCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCC
GMVVGINPRAEDLDINVTREKKLTNMRSSTGDVLETLARPLVLDLEGALEFCAADECVEV
CEEEEECCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHHCCHHHHC
GPDVVRVRKVILNANERARELSRRKARDRAAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSARDFRNVAIVAHVDHGKTTLVDAMLRQSGAFAERAEPVDRVMDSGDLEREKGITILA
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHCCHHHHHHCCCCCHHHCCCEEEE
KNTAVHRHHPDGSVTVINVIDTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVL
ECCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
RKALAASLPVILVVNKTDRPDARIAEVVEESHDLLLDLASDLDDEAAEAAELALDLPVLY
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEE
ASGREGKASTERPENGNAPDAPNLDALFDVLLKHVPAPKGDAQAPLQAHVTNLDASPFLG
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCC
RLALVRIHNGTLKKGQNVAWMSAEGTKTVKITELLATVGVERNPAEEAEAGDIVAVAGIP
EEEEEEEECCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
DIMIGDTLADPDNPVALPRITVDEPAISVTIGINTSPLAGRNGGTKLTARLLKARLDQEL
CEEECCCCCCCCCCEECCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHH
VGNVSLRVLNTDRPDTWEVQGRGELALAILVETMRREGFELTVGKPQVVTRMVDGKVHEP
HCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCCCC
FEELTIDVPEEHLGAVTQLLAARKGKMVQMTNQGHGWVRMEFIVPSRGLIGFRTDFLTET
HHHCEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEEEHHHHHHC
RGTGIANAVAHGYAPWAGEIRSRHTGSLVSDRAGSVTAYAMLQLADRGTFFVEPGAETYE
CCCCHHHHHHCCCCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCC
GMVVGINPRAEDLDINVTREKKLTNMRSSTGDVLETLARPLVLDLEGALEFCAADECVEV
CEEEEECCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHHCCHHHHC
GPDVVRVRKVILNANERARELSRRKARDRAAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]