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The map label for this gene is pimE [H]

Identifier: 54026736

GI number: 54026736

Start: 4973847

End: 4975091

Strand: Reverse

Name: pimE [H]

Synonym: nfa47620

Alternate gene names: 54026736

Gene position: 4975091-4973847 (Counterclockwise)

Preceding gene: 54026739

Following gene: 54026733

Centisome position: 82.63

GC content: 70.36

Gene sequence:

>1245_bases
TTGAACCGAGAGAGCGCTCGGACGGACGCACGTCCGGCCGCTGCCCCCCTGCGAACGGCGCTGGCGTTGCTCGGCCTCTC
GGTGCTGGCCCGGATGCTGTGGATGCTGTTGTCCGACAACGGGATGAATCTGGTCGACCTGCACGTCTACGTGGACGGCT
CGGCCTCGGTGCTCACCGACCGGCTCTACGACTTCACCTATGCGGAGAAGACACCCGACTTCCCGCTGCCCTTCACGTAT
CCGCCGTTCGCCGCGCTGGTGTTCTCGCCGCTGCATTTCCTGCCCTTCACCGTCATCGCGGTCGGCTGGCTGCTGGCCAC
GGTGGCCGCGCTGTACGGGGTGGTGCGGATCTCACTGGAGTTGCTGCTCGGTCGCGAGCGGTTGCGCGAGCCGGGCTGGC
GCACCGCGACGGTGGCCTGGACGGCGGTCGGGGTGTGGCTGGAGCCGGTGCGCACCACCCTGGACTACGGGCAGGTGAAC
GTCTTCCTGGTGCTCGGGGCGATGCTCGCGGTGCGCAACTCGCGCTGGTGGGTCTCCGGTGGGCTCGTCGGGCTGATCGC
CGGTATCAAGCTGACACCGGCGATCACGGGGCTGTACTTCGTGGCGCGCAGGCGCTGGGGCGCCGCGGTGTTCTCCGCGG
TGGCCTTCGGCGGCACCGTGGCGATCAGCTATCTGCTCAACAATCACGAGGCCACCCGCTACTTCGGCACCCTGCTCGGC
GACGCGGACCGCATCGGACCGGTGGCCTCGGTGTGGAATCAGTCGCTGCGCGGGACGCTGAGCCGGATCCTCGGCTACGA
CGTGGAGACCGGGCCGATCTGGATCGCGGCGGTGCTGCTGGTCGCGGTGCCTGCGTTCTTCGCGTGGCGGGCGCTCGGCC
CCGACGACCTGCTCGGCACGCTGCTCGTGGTGCAGTTGTTCGGGCTGCTGGTCTCGCCGATCTCGTGGTCGCACCACTGG
GTGTGGTTGCTGCCGCTGGTGCTGTGGCTGGTGTACGGGCCACTGCGGCAGGCGCCGGGCGCGCGGGTGCTGGCCGGTTA
CTGGCTGCTGACCATGCTGGTGGGCGTGCCGTGGGTGCTGTCGTTCTTCCAGCCGACGATCTGGGAGATCTCCCGGCCCG
GCCTGCTGTCCTGGCTGGGTGCGGTGGACGTGCTCGGCGTGCTGGCCTGCTACGTCTGGGTGATCGTGGCGGGCAGGCGC
GCGCGGGCCACCGCGCCCGAGCCGGAGCGGGCCGGGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGGTTAATCTAGTCATCACCTTCGGCTCGCGTGCGCCGAACACTCCGAAACACCCCCGGCCGCGCCGGCGACCCGCACAC
CACCTCCGAAAGCCTGCGAT

Downstream 100 bases:

>100_bases
CTAGCGCGCGAGTTCGTCGATCTGCCGGGCGAGATCGATGTCGCGGCCGGTGAGTCCGCCGGCGGAATGGGTGGACAAGG
TGAAGGTGACGGTGCGCCAG

Product: mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNRESARTDARPAAAPLRTALALLGLSVLARMLWMLLSDNGMNLVDLHVYVDGSASVLTDRLYDFTYAEKTPDFPLPFTY
PPFAALVFSPLHFLPFTVIAVGWLLATVAALYGVVRISLELLLGRERLREPGWRTATVAWTAVGVWLEPVRTTLDYGQVN
VFLVLGAMLAVRNSRWWVSGGLVGLIAGIKLTPAITGLYFVARRRWGAAVFSAVAFGGTVAISYLLNNHEATRYFGTLLG
DADRIGPVASVWNQSLRGTLSRILGYDVETGPIWIAAVLLVAVPAFFAWRALGPDDLLGTLLVVQLFGLLVSPISWSHHW
VWLLPLVLWLVYGPLRQAPGARVLAGYWLLTMLVGVPWVLSFFQPTIWEISRPGLLSWLGAVDVLGVLACYVWVIVAGRR
ARATAPEPERAGLR

Sequences:

>Translated_414_residues
MNRESARTDARPAAAPLRTALALLGLSVLARMLWMLLSDNGMNLVDLHVYVDGSASVLTDRLYDFTYAEKTPDFPLPFTY
PPFAALVFSPLHFLPFTVIAVGWLLATVAALYGVVRISLELLLGRERLREPGWRTATVAWTAVGVWLEPVRTTLDYGQVN
VFLVLGAMLAVRNSRWWVSGGLVGLIAGIKLTPAITGLYFVARRRWGAAVFSAVAFGGTVAISYLLNNHEATRYFGTLLG
DADRIGPVASVWNQSLRGTLSRILGYDVETGPIWIAAVLLVAVPAFFAWRALGPDDLLGTLLVVQLFGLLVSPISWSHHW
VWLLPLVLWLVYGPLRQAPGARVLAGYWLLTMLVGVPWVLSFFQPTIWEISRPGLLSWLGAVDVLGVLACYVWVIVAGRR
ARATAPEPERAGLR
>Mature_414_residues
MNRESARTDARPAAAPLRTALALLGLSVLARMLWMLLSDNGMNLVDLHVYVDGSASVLTDRLYDFTYAEKTPDFPLPFTY
PPFAALVFSPLHFLPFTVIAVGWLLATVAALYGVVRISLELLLGRERLREPGWRTATVAWTAVGVWLEPVRTTLDYGQVN
VFLVLGAMLAVRNSRWWVSGGLVGLIAGIKLTPAITGLYFVARRRWGAAVFSAVAFGGTVAISYLLNNHEATRYFGTLLG
DADRIGPVASVWNQSLRGTLSRILGYDVETGPIWIAAVLLVAVPAFFAWRALGPDDLLGTLLVVQLFGLLVSPISWSHHW
VWLLPLVLWLVYGPLRQAPGARVLAGYWLLTMLVGVPWVLSFFQPTIWEISRPGLLSWLGAVDVLGVLACYVWVIVAGRR
ARATAPEPERAGLR

Specific function: Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PIGM family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 45469; Mature: 45469

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRESARTDARPAAAPLRTALALLGLSVLARMLWMLLSDNGMNLVDLHVYVDGSASVLTD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHH
RLYDFTYAEKTPDFPLPFTYPPFAALVFSPLHFLPFTVIAVGWLLATVAALYGVVRISLE
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGRERLREPGWRTATVAWTAVGVWLEPVRTTLDYGQVNVFLVLGAMLAVRNSRWWVSG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECC
GLVGLIAGIKLTPAITGLYFVARRRWGAAVFSAVAFGGTVAISYLLNNHEATRYFGTLLG
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
DADRIGPVASVWNQSLRGTLSRILGYDVETGPIWIAAVLLVAVPAFFAWRALGPDDLLGT
CCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLVVQLFGLLVSPISWSHHWVWLLPLVLWLVYGPLRQAPGARVLAGYWLLTMLVGVPWVL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SFFQPTIWEISRPGLLSWLGAVDVLGVLACYVWVIVAGRRARATAPEPERAGLR
HHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRESARTDARPAAAPLRTALALLGLSVLARMLWMLLSDNGMNLVDLHVYVDGSASVLTD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHH
RLYDFTYAEKTPDFPLPFTYPPFAALVFSPLHFLPFTVIAVGWLLATVAALYGVVRISLE
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGRERLREPGWRTATVAWTAVGVWLEPVRTTLDYGQVNVFLVLGAMLAVRNSRWWVSG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECC
GLVGLIAGIKLTPAITGLYFVARRRWGAAVFSAVAFGGTVAISYLLNNHEATRYFGTLLG
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
DADRIGPVASVWNQSLRGTLSRILGYDVETGPIWIAAVLLVAVPAFFAWRALGPDDLLGT
CCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLVVQLFGLLVSPISWSHHWVWLLPLVLWLVYGPLRQAPGARVLAGYWLLTMLVGVPWVL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SFFQPTIWEISRPGLLSWLGAVDVLGVLACYVWVIVAGRRARATAPEPERAGLR
HHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]