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The map label for this gene is dapE [H]

Identifier: 54026715

GI number: 54026715

Start: 4951983

End: 4953083

Strand: Reverse

Name: dapE [H]

Synonym: nfa47410

Alternate gene names: 54026715

Gene position: 4953083-4951983 (Counterclockwise)

Preceding gene: 54026717

Following gene: 54026714

Centisome position: 82.26

GC content: 72.75

Gene sequence:

>1101_bases
GTGACCATCGACCTGTCCGCCGATCCCATCGCCCTCACCGCCGCCCTCGTCGACATCCCCAGCGTCTCACTGGACGAGCG
CGCGATCGCGGATGTCGTGGAACGGGCGCTGCGTGAGCAGACCACCGGGTTCGAGGTGCTGCGGCACGGCAACGTCGTGC
TCGCCCGCACCCGGCGCGGCCTGCCGACCCGGGTGATCCTGGCCGGGCACCTGGACACCGTGCCGATCGCCGACAACGTG
CCGAGCCGCTTCGGCACCGGCCCCGACGGCGAGCAGCTGCTGCACGGCTGCGGCACCGTCGACATGAAGTCCGGCGACGC
GGTGTTCCTGCACCTGGCCGCGACGGTGACCGACCCCGTGCACGACCTCACCTTGATCTTCTACGACGGCGAGGAGATCG
CCGCCGAGTACAACGGCCTCGGCCACATCGAACGCGACCTGCCCGAATGGCTCGACGGCGACCTGGCCGTGCTCGGCGAA
CCCTCCGGCGGCTGGATCGAGGCGGGCTGCCAGGGCACGCTGCGGGTGCGGCTGCGCACCGCGGGCGTGCGGGCGCATTC
GGCACGGGCCTGGATGGGTGACAACGCGATCCACCGGCTGGCGCCGGTGCTGGCGCGGCTGGCCGACTACCGAGCCAGGC
AGGTCGACATCGACGGCTGCGTGTACCGCGAAGGCCTGTCCGCGGTGGCGGTGCGCGGCGGGGTGGCCGGCAACGTGATC
CCCGATGTCGGTGAGGTGGACGTCAACTTCCGCTTCGCCCCCGACCGTGACCTGGACCAGGCGATCGCCCACGTGCGCGA
GGTGTTCGCCGGGCTGGAGGTGGAGTTCGAGGTGACCGACGCCGCACCGGGCGCGCTGCCCGGCCTCACCGCGCCGGCGG
CCAAGGCGCTCGTCGAGTCGGTGAACGCGCACGGCGGCGGTGGGGTGCGGGCCAAGTACGGCTGGACCGACGTGTCGCGC
TTCGCCGCCCGCGGCATCCCCGCGGTGAACTTCGGTCCGGGCGATCCGAACCTGGCCCACAAGCGCGACGAGCACGTGCC
GACCGCGCAGATCACCGCGGTCACCGCGATGCTGCGCGCCTACCTCACCGGCGCGGTCTGA

Upstream 100 bases:

>100_bases
CGATGCCGACTGCTGTTGCTCCCTGAGTGCTCACGTCGTCAGAGGTTACCCACCCGCCCGGCGCCCGTGGTGGGCTACCT
CGCGGTCGTAGGCTGGCCCG

Downstream 100 bases:

>100_bases
GCGCGTCACCGAGCATCCGCTCGGCGTTCACCGCCGCGGCCGTGTGCGGTGGCACCGGACCGGTAGCGTGAAAGCATGTC
GATCGATGTCCCCGAGAACG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTIDLSADPIALTAALVDIPSVSLDERAIADVVERALREQTTGFEVLRHGNVVLARTRRGLPTRVILAGHLDTVPIADNV
PSRFGTGPDGEQLLHGCGTVDMKSGDAVFLHLAATVTDPVHDLTLIFYDGEEIAAEYNGLGHIERDLPEWLDGDLAVLGE
PSGGWIEAGCQGTLRVRLRTAGVRAHSARAWMGDNAIHRLAPVLARLADYRARQVDIDGCVYREGLSAVAVRGGVAGNVI
PDVGEVDVNFRFAPDRDLDQAIAHVREVFAGLEVEFEVTDAAPGALPGLTAPAAKALVESVNAHGGGGVRAKYGWTDVSR
FAARGIPAVNFGPGDPNLAHKRDEHVPTAQITAVTAMLRAYLTGAV

Sequences:

>Translated_366_residues
MTIDLSADPIALTAALVDIPSVSLDERAIADVVERALREQTTGFEVLRHGNVVLARTRRGLPTRVILAGHLDTVPIADNV
PSRFGTGPDGEQLLHGCGTVDMKSGDAVFLHLAATVTDPVHDLTLIFYDGEEIAAEYNGLGHIERDLPEWLDGDLAVLGE
PSGGWIEAGCQGTLRVRLRTAGVRAHSARAWMGDNAIHRLAPVLARLADYRARQVDIDGCVYREGLSAVAVRGGVAGNVI
PDVGEVDVNFRFAPDRDLDQAIAHVREVFAGLEVEFEVTDAAPGALPGLTAPAAKALVESVNAHGGGGVRAKYGWTDVSR
FAARGIPAVNFGPGDPNLAHKRDEHVPTAQITAVTAMLRAYLTGAV
>Mature_365_residues
TIDLSADPIALTAALVDIPSVSLDERAIADVVERALREQTTGFEVLRHGNVVLARTRRGLPTRVILAGHLDTVPIADNVP
SRFGTGPDGEQLLHGCGTVDMKSGDAVFLHLAATVTDPVHDLTLIFYDGEEIAAEYNGLGHIERDLPEWLDGDLAVLGEP
SGGWIEAGCQGTLRVRLRTAGVRAHSARAWMGDNAIHRLAPVLARLADYRARQVDIDGCVYREGLSAVAVRGGVAGNVIP
DVGEVDVNFRFAPDRDLDQAIAHVREVFAGLEVEFEVTDAAPGALPGLTAPAAKALVESVNAHGGGGVRAKYGWTDVSRF
AARGIPAVNFGPGDPNLAHKRDEHVPTAQITAVTAMLRAYLTGAV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=392, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010174 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 38778; Mature: 38647

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDLSADPIALTAALVDIPSVSLDERAIADVVERALREQTTGFEVLRHGNVVLARTRRG
CEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCC
LPTRVILAGHLDTVPIADNVPSRFGTGPDGEQLLHGCGTVDMKSGDAVFLHLAATVTDPV
CCEEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHHCCCEEECCCCEEEEEEEEHHCCCC
HDLTLIFYDGEEIAAEYNGLGHIERDLPEWLDGDLAVLGEPSGGWIEAGCQGTLRVRLRT
CEEEEEEECCHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCEEECCCCEEEEEEEEE
AGVRAHSARAWMGDNAIHRLAPVLARLADYRARQVDIDGCVYREGLSAVAVRGGVAGNVI
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCHHEEECCCCCCCCC
PDVGEVDVNFRFAPDRDLDQAIAHVREVFAGLEVEFEVTDAAPGALPGLTAPAAKALVES
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
VNAHGGGGVRAKYGWTDVSRFAARGIPAVNFGPGDPNLAHKRDEHVPTAQITAVTAMLRA
HCCCCCCCCEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLTGAV
HHHCCC
>Mature Secondary Structure 
TIDLSADPIALTAALVDIPSVSLDERAIADVVERALREQTTGFEVLRHGNVVLARTRRG
EEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCC
LPTRVILAGHLDTVPIADNVPSRFGTGPDGEQLLHGCGTVDMKSGDAVFLHLAATVTDPV
CCEEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHHCCCEEECCCCEEEEEEEEHHCCCC
HDLTLIFYDGEEIAAEYNGLGHIERDLPEWLDGDLAVLGEPSGGWIEAGCQGTLRVRLRT
CEEEEEEECCHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCEEECCCCEEEEEEEEE
AGVRAHSARAWMGDNAIHRLAPVLARLADYRARQVDIDGCVYREGLSAVAVRGGVAGNVI
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCHHEEECCCCCCCCC
PDVGEVDVNFRFAPDRDLDQAIAHVREVFAGLEVEFEVTDAAPGALPGLTAPAAKALVES
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
VNAHGGGGVRAKYGWTDVSRFAARGIPAVNFGPGDPNLAHKRDEHVPTAQITAVTAMLRA
HCCCCCCCCEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLTGAV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7881553; 12948626; 7592354 [H]