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The map label for this gene is emrY [C]

Identifier: 54026679

GI number: 54026679

Start: 4916903

End: 4918375

Strand: Reverse

Name: emrY [C]

Synonym: nfa47060

Alternate gene names: 54026679

Gene position: 4918375-4916903 (Counterclockwise)

Preceding gene: 54026680

Following gene: 54026673

Centisome position: 81.68

GC content: 70.4

Gene sequence:

>1473_bases
GTGTCGACCCAACGCAATCCGTGGCTGGCGCTGTTCGCGCTGGTCGTCGGCTTCTTCATGATCCTGTTGGACATGACCAT
CGTCGCGGTCGCCAACCCGGCGATCATGACCGACCTCGGCGCCGACATCTCCCAGGTCATCTGGGTGACCAGCGCCTACC
TGCTCACCTACGCCGTGCCGCTGCTCATCACCGGCCGCCTCGGTGACCGCTTCGGCCCCAAGAACATCTACCTGGCCGGT
CTGGCCGTGTTCACCGCTGCCTCGCTGTGGTGCGGCATGTCGAACAGCATCGAGATGCTGATCGCCGCGCGCGCCGTGCA
GGGCCTCGGCGCGGCGCTGATGACCCCGCAGACGATGGCGGTGATCACCCGCACCTTCCCGCCGGACAAGCGCGGCGCCG
CGATGGGGCTGTGGGGCGGCGTCGCGGGCCTGGCCACCCTGGTCGGGCCGATCCTCGGCGGCGTGCTGGTGGACGGCTTG
AGCTGGGAGTGGATCTTCATCGTCAACGTGCCGGTCGGCGTGCTCGCCTTCGCGCTGGCGGTGTGGCTGGTGCCCGCCCT
GCCCACCCACGAGCACAAGTTCGACATCCCCGGCGTCGTGCTCAGCGGACTCGGCATGTTCCTGCTGGTGTTCGGCATCC
AGGAGGGCAACACCTACGACTGGTCGGTGCGCATCTGGCTGCTGATCGTCGCGGGCATCGTGGTGCTGGGGCTGTTCGTG
GTCAACCAGGCGCGCAACACCGGCGAGCCGCTGGTCCCGCTCGGCCTGTTCCGGGTCCGCAACTTCGCGCTGTCCAACAT
CGCCATCGCCGCCATGGGCGCGGCCGTGACCGGGTTGATGGTGCCGGTCTACTTCTACCTCCAGGCGGTGCGCGACATGT
CGCCGACCAAGTCGGCGCTGGTGCTGGCGCCGATGGCGGTCGTCACCGGTTTCGCGGCGCCGGTCCTCGGTCGCTTCGCC
GACCGGCTCGCGCCGCGCATCCTGCCCACCATCGGGTTCGCGTTGTTCGCCGCGGTGATCTTCTGGTGGGCGGCGATCAT
GACGCCGGACTCGGAGCTGGCCCTGTTCCTGGTGTCGGCGGGCTTCGCCGGTTTCGCCAACGCCTGCATCTGGGGTCCGC
TGGCGGCCACCGCGACGCACAACCTGCCGGTGCAGCAGGCGGGCGCGGGCTCGGGCATCTACAACACCACCCGCCAAGTC
GGTTCGGTGCTCGGCAGCGCGGCGATCAGCGCGTTGATCGCGTCCCGGATGTCGGCGCACGGGCTCGGCGGCGGCCGGGT
CGCCGAAGGCGGCGTCGGTCAGGGCCCGATCCCGCCGCACGTGCTCGACGAATTCAGCGCGGCGCTGTCGGAATCGATGA
TCCTGCCCGCCGCCGTCCTGCTCGTCGGCGTGCTGGCCTCGGCGCTGTTCATCGGCCACGGCCCGCGCACCACGGCCGAC
CAGCCCACCGCCGCGGACGCCGTCTCCGCCTGA

Upstream 100 bases:

>100_bases
GCGACGAGGCCGACCCGCCCCCGGCGCCGCGCCGCGCGCACGCCGCCCCGCCGCCATCCCCCTCGATCGTCCAGATCGCC
CCCAGATAGGAAGCACTTCC

Downstream 100 bases:

>100_bases
CCGGCGCGGCGGTGGTCAGCTCACCCGCACGGTGACGCTCGGATAACCGGTCGCGCCGTCCGGCAGGACATCGGCGACCT
CGGCGGTCTGGACCGCGCCG

Product: putative transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSTQRNPWLALFALVVGFFMILLDMTIVAVANPAIMTDLGADISQVIWVTSAYLLTYAVPLLITGRLGDRFGPKNIYLAG
LAVFTAASLWCGMSNSIEMLIAARAVQGLGAALMTPQTMAVITRTFPPDKRGAAMGLWGGVAGLATLVGPILGGVLVDGL
SWEWIFIVNVPVGVLAFALAVWLVPALPTHEHKFDIPGVVLSGLGMFLLVFGIQEGNTYDWSVRIWLLIVAGIVVLGLFV
VNQARNTGEPLVPLGLFRVRNFALSNIAIAAMGAAVTGLMVPVYFYLQAVRDMSPTKSALVLAPMAVVTGFAAPVLGRFA
DRLAPRILPTIGFALFAAVIFWWAAIMTPDSELALFLVSAGFAGFANACIWGPLAATATHNLPVQQAGAGSGIYNTTRQV
GSVLGSAAISALIASRMSAHGLGGGRVAEGGVGQGPIPPHVLDEFSAALSESMILPAAVLLVGVLASALFIGHGPRTTAD
QPTAADAVSA

Sequences:

>Translated_490_residues
MSTQRNPWLALFALVVGFFMILLDMTIVAVANPAIMTDLGADISQVIWVTSAYLLTYAVPLLITGRLGDRFGPKNIYLAG
LAVFTAASLWCGMSNSIEMLIAARAVQGLGAALMTPQTMAVITRTFPPDKRGAAMGLWGGVAGLATLVGPILGGVLVDGL
SWEWIFIVNVPVGVLAFALAVWLVPALPTHEHKFDIPGVVLSGLGMFLLVFGIQEGNTYDWSVRIWLLIVAGIVVLGLFV
VNQARNTGEPLVPLGLFRVRNFALSNIAIAAMGAAVTGLMVPVYFYLQAVRDMSPTKSALVLAPMAVVTGFAAPVLGRFA
DRLAPRILPTIGFALFAAVIFWWAAIMTPDSELALFLVSAGFAGFANACIWGPLAATATHNLPVQQAGAGSGIYNTTRQV
GSVLGSAAISALIASRMSAHGLGGGRVAEGGVGQGPIPPHVLDEFSAALSESMILPAAVLLVGVLASALFIGHGPRTTAD
QPTAADAVSA
>Mature_489_residues
STQRNPWLALFALVVGFFMILLDMTIVAVANPAIMTDLGADISQVIWVTSAYLLTYAVPLLITGRLGDRFGPKNIYLAGL
AVFTAASLWCGMSNSIEMLIAARAVQGLGAALMTPQTMAVITRTFPPDKRGAAMGLWGGVAGLATLVGPILGGVLVDGLS
WEWIFIVNVPVGVLAFALAVWLVPALPTHEHKFDIPGVVLSGLGMFLLVFGIQEGNTYDWSVRIWLLIVAGIVVLGLFVV
NQARNTGEPLVPLGLFRVRNFALSNIAIAAMGAAVTGLMVPVYFYLQAVRDMSPTKSALVLAPMAVVTGFAAPVLGRFAD
RLAPRILPTIGFALFAAVIFWWAAIMTPDSELALFLVSAGFAGFANACIWGPLAATATHNLPVQQAGAGSGIYNTTRQVG
SVLGSAAISALIASRMSAHGLGGGRVAEGGVGQGPIPPHVLDEFSAALSESMILPAAVLLVGVLASALFIGHGPRTTADQ
PTAADAVSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=416, Percent_Identity=30.2884615384615, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789042, Length=417, Percent_Identity=31.6546762589928, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87081983, Length=425, Percent_Identity=30.8235294117647, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1790195, Length=413, Percent_Identity=28.0871670702179, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788392, Length=418, Percent_Identity=30.1435406698565, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790146, Length=189, Percent_Identity=27.5132275132275, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=173, Percent_Identity=28.3236994219653, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788509, Length=168, Percent_Identity=30.952380952381, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367379, Length=184, Percent_Identity=27.1739130434783, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=336, Percent_Identity=23.8095238095238, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324954, Length=294, Percent_Identity=28.9115646258503, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=215, Percent_Identity=27.4418604651163, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321663, Length=173, Percent_Identity=30.0578034682081, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323520, Length=266, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322958, Length=249, Percent_Identity=24.4979919678715, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=536, Percent_Identity=22.0149253731343, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50982; Mature: 50851

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQRNPWLALFALVVGFFMILLDMTIVAVANPAIMTDLGADISQVIWVTSAYLLTYAVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLITGRLGDRFGPKNIYLAGLAVFTAASLWCGMSNSIEMLIAARAVQGLGAALMTPQTMA
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHH
VITRTFPPDKRGAAMGLWGGVAGLATLVGPILGGVLVDGLSWEWIFIVNVPVGVLAFALA
HHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHH
VWLVPALPTHEHKFDIPGVVLSGLGMFLLVFGIQEGNTYDWSVRIWLLIVAGIVVLGLFV
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
VNQARNTGEPLVPLGLFRVRNFALSNIAIAAMGAAVTGLMVPVYFYLQAVRDMSPTKSAL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VLAPMAVVTGFAAPVLGRFADRLAPRILPTIGFALFAAVIFWWAAIMTPDSELALFLVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GFAGFANACIWGPLAATATHNLPVQQAGAGSGIYNTTRQVGSVLGSAAISALIASRMSAH
CCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGGGRVAEGGVGQGPIPPHVLDEFSAALSESMILPAAVLLVGVLASALFIGHGPRTTAD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QPTAADAVSA
CCCCHHHCCC
>Mature Secondary Structure 
STQRNPWLALFALVVGFFMILLDMTIVAVANPAIMTDLGADISQVIWVTSAYLLTYAVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH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CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]