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The map label for this gene is nrdF [H]

Identifier: 54026269

GI number: 54026269

Start: 4452892

End: 4453854

Strand: Reverse

Name: nrdF [H]

Synonym: nfa42980

Alternate gene names: 54026269

Gene position: 4453854-4452892 (Counterclockwise)

Preceding gene: 54026270

Following gene: 54026265

Centisome position: 73.97

GC content: 63.03

Gene sequence:

>963_bases
ATGAAACTGATCGATCGGGTGTCGGCCATCAACTGGAATCGGGTGCCCGACGAGAAGGACGCCGAGGTCTGGGCTCGGCT
GACCGGCAACTTCTGGCTGCCGGAGAAGGTGCCGGTGTCCAACGACATCCCCTCGTGGAACACGCTGACCCCGCACGAGC
AGCAGCTGACCATGCGGGTCTTCACCGGCCTGACGCTGCTGGACACCATCCAGGGCACCGTCGGCGCGGTGAGCCTCATC
CCGGACGCGCTGACGCCGCACGAGGAAGCGGTGCTCACCAACATCGCGTTCATGGAGTCGGTGCACGCCAAGAGCTACAG
CTCGATCTTCTCCACGCTGTGTTCCACCAAGGAGATCGACGAGGCGTTCCGCTGGTCGGAGGAGAACCGGAATCTCCAGC
GCAAGGCCGAGATCGTCCTCGACTATTACCAGGGCGACGACCCGCTCAAGCGCAAGGTGGCCTCCACCCTGCTGGAGAGC
TTCCTGTTCTACTCCGGCTTCTACCTGCCGATGCACTGGTCCTCGCGGGCCAAACTCACCAACACCGCCGACATGATCCG
GCTGATCATCCGCGACGAGGCGGTGCACGGCTACTACATCGGCTACAAGTACCAGCGCGGCCTGGAACAGGTGTCCGAGG
CCGAGCGTGAGGAGCTGAAGAACTACACCTTCGAGCTGCTCTACGAGCTCTACGAGAACGAGGTCGAATACACCCAGGAC
CTCTACGACGAGGTCGGCCTCACCGAGGACGTCAAGACCTTCCTGCGCTACAACGCGAACAAGGCGCTGATGAACCTCGG
GTACGAGGGCCTGTTCCCGGCCGACGAGACCAGGGTGAACCCGGCGATCCTGTCCGCGCTCTCGCCGAACGCCGACGAGA
ACCACGACTTCTTCTCCGGTTCCGGCTCCAGCTACGTCATCGGCAAGGCCGTCAACACCGAGGACGAGGACTGGGACTTC
TGA

Upstream 100 bases:

>100_bases
GTTGTCGGACACAACGAGTAGTGTCTGACTGGGTAGGTACTCGGTGACCGCGGGGTGTCCGGAGAACCGCAGTGTGTTCG
GGAAAGGGTGTGGAGGCAGC

Downstream 100 bases:

>100_bases
GTCCGTAGGCACCGCCCCGGCCCCGCGGGACACGCGGGGTGGGTCAGCGACCGCGCGGCGGCGCGCCACCGGGCGCCATC
GGGTTGCGCGGGGTGTTCTG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKLIDRVSAINWNRVPDEKDAEVWARLTGNFWLPEKVPVSNDIPSWNTLTPHEQQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVLTNIAFMESVHAKSYSSIFSTLCSTKEIDEAFRWSEENRNLQRKAEIVLDYYQGDDPLKRKVASTLLES
FLFYSGFYLPMHWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKYQRGLEQVSEAEREELKNYTFELLYELYENEVEYTQD
LYDEVGLTEDVKTFLRYNANKALMNLGYEGLFPADETRVNPAILSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF

Sequences:

>Translated_320_residues
MKLIDRVSAINWNRVPDEKDAEVWARLTGNFWLPEKVPVSNDIPSWNTLTPHEQQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVLTNIAFMESVHAKSYSSIFSTLCSTKEIDEAFRWSEENRNLQRKAEIVLDYYQGDDPLKRKVASTLLES
FLFYSGFYLPMHWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKYQRGLEQVSEAEREELKNYTFELLYELYENEVEYTQD
LYDEVGLTEDVKTFLRYNANKALMNLGYEGLFPADETRVNPAILSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
>Mature_320_residues
MKLIDRVSAINWNRVPDEKDAEVWARLTGNFWLPEKVPVSNDIPSWNTLTPHEQQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVLTNIAFMESVHAKSYSSIFSTLCSTKEIDEAFRWSEENRNLQRKAEIVLDYYQGDDPLKRKVASTLLES
FLFYSGFYLPMHWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKYQRGLEQVSEAEREELKNYTFELLYELYENEVEYTQD
LYDEVGLTEDVKTFLRYNANKALMNLGYEGLFPADETRVNPAILSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=320, Percent_Identity=74.0625, Blast_Score=506, Evalue=1e-145,
Organism=Escherichia coli, GI1788567, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 36743; Mature: 36743

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIDRVSAINWNRVPDEKDAEVWARLTGNFWLPEKVPVSNDIPSWNTLTPHEQQLTMRV
CCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
FTGLTLLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSSIFSTLCSTKEID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EAFRWSEENRNLQRKAEIVLDYYQGDDPLKRKVASTLLESFLFYSGFYLPMHWSSRAKLT
HHHHCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
NTADMIRLIIRDEAVHGYYIGYKYQRGLEQVSEAEREELKNYTFELLYELYENEVEYTQD
HHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYDEVGLTEDVKTFLRYNANKALMNLGYEGLFPADETRVNPAILSALSPNADENHDFFSG
HHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
SGSSYVIGKAVNTEDEDWDF
CCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKLIDRVSAINWNRVPDEKDAEVWARLTGNFWLPEKVPVSNDIPSWNTLTPHEQQLTMRV
CCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
FTGLTLLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSSIFSTLCSTKEID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EAFRWSEENRNLQRKAEIVLDYYQGDDPLKRKVASTLLESFLFYSGFYLPMHWSSRAKLT
HHHHCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
NTADMIRLIIRDEAVHGYYIGYKYQRGLEQVSEAEREELKNYTFELLYELYENEVEYTQD
HHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYDEVGLTEDVKTFLRYNANKALMNLGYEGLFPADETRVNPAILSALSPNADENHDFFSG
HHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
SGSSYVIGKAVNTEDEDWDF
CCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]