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The map label for this gene is ctaD1

Identifier: 54026265

GI number: 54026265

Start: 4447920

End: 4449665

Strand: Reverse

Name: ctaD1

Synonym: nfa42940

Alternate gene names: 54026265

Gene position: 4449665-4447920 (Counterclockwise)

Preceding gene: 54026269

Following gene: 54026264

Centisome position: 73.9

GC content: 65.58

Gene sequence:

>1746_bases
GTGACTGCGGTAGAGCCCAGACCAGTCCCTCAGTTGGAAGCGACTCGACCGTATCCGGCACGGACCGGACCCAAGGGTTC
TTTCCTCTACAAGATGGTCACCACGACCGACCCGAAGGTGCTCGGCACCATGTACCTGGTGACCGCCATGAGCTTCTTCA
TGATCGGCGGTCTGATGGCCCTGCTGATGCGTGGTGAGCTGGCGCGCCCGGGTCTGCAGTTCCTCTCGCCCGAGCAGTTC
AACCAGCTGTTCACCATGCACGGCACGATCATGCTGCTGTTCTACGCGACCGCGATCGTGTTCGGCTTCGCCAACATCAT
CCTGCCGCTGCAGATCGGCGCCCCCGACGTCGCCTTCCCGCGCCTGAACGCCTTCAGCTACTGGCTCTACGCGTTCGGCG
CCACCATGGCCACCGCGGGCTTCATAACCCCCGGCGGCGCGGCCGACTTCGGCTGGACCGCCTACGTGCCGCTGACCGAC
ATCCTGCACTCGCCCGGTGTCGGCACCGACCTGTGGATCCTCGGCCTCGCCGTCTCCGGTCTGGGCACCATCCTGGGCGG
CGTGAACATGCTGACCACCGTCGTCTGCTTGCGCGCCCCCGGCATGACCATGTTCCGGATGCCGATCTTCACCTGGAACA
TCGCCGTCACCAGCGTGCTGGTGCTGCTGGCCTTCCCGCTGCTCACCGCGGCCCTGTTCGGCCTGGCCTACGACCGCCAC
CTGGGCGGGCACATCTACGACCCGGCCACCGGCGGCATCCTGCTCTACCAGCACCTGTTCTGGTTCTTCGGCCACCCCGA
GGTCTACATCATCGCGCTGCCGTTCTTCGGCATCGTCTCCGAGATCTTCCCGGTGTTCAGCCGCAAGCCGATCTTCGGCT
ACACCACCCTGGTGTACGCGACCCTGGGCATCGCCGCGCTGTCCATCGCCGTGTGGGCGCACCACATGTACGCCACCGGC
GCGGTGCTGCTGCCGTACTTCTCGTTCATGACCTTCCTCATCGCGGTCCCGACCGGCGTGAAGTTCTTCAACTGGATCGG
CACCATGTGGCGGGGTCAGCTGACCTTCGAATCGCCGATGCTGTGGTCGCTGGGCTTCCTGGTGACCTTCCTCTTCGGTG
GTCTGTCCGGCGTCATCCTGGCCAGCCCGCCGCTGGACTTCCACGTCACCGACTCCTACTTCGTGGTCGCCCACTTCCAC
TACGTGCTCTTCGGCACCATCGTGTTCGCCACCTTCGCCGGCATCTACTTCTGGTTCCCGAAGATCACCGGCCGCATGGT
GGACGAGCGCCTGGCCAAGTGGCACTTCTGGGCCACCTTCGTCGGCTTCCACACCACCTTCCTGGTGCAGCACTGGCTGG
GTGCGGAGGGTATGCCGCGCCGCTACGCCGACTACCTGCCCTCGGACGGCTTCACCACGCTGAACACGATCTCCACCATC
GGCGCGTTCGTGCTCGGCGCCTCGATGCTGCCGTTCATCTGGAACATCTTCAAGAGCTACCGCTACGGTGAGGTCGTCAC
CGTGGACGACCCGTGGGGTTACGGCAACTCGCTGGAGTGGGCCACCACCTGCCCGCCGCCGCGGCACAACTTCTACGAGC
TGCCGCGCATCCGGTCCGAGCGTCCGGCCTTCGAGCTGCACTACCCGCACATGATCGAGCGCATGCGCGCCGAGGCGCAC
GTGGGCTGGGGCTCGGGCAAGCACGGGACCCCGCAGGACGACGACGCGTTGCTGGCGAAGAAGTAA

Upstream 100 bases:

>100_bases
GATCTGTGGAGCGCAAGCGAACTGTCCGCTGTTCCGGTAACGGGATGTGTGCGAGCAGCGGAGCCTGCGGAGCGACCTAA
AGGCACCTTCAGGAGGATCA

Downstream 100 bases:

>100_bases
CGACGACGACTGTGCACCCGCTGGGCCCCAGCGGGTGCACACTCGTGTGACGAGCAGAAAGACTTGGAGCGCACCGACGT
GGCCGACACCACCGTTCTCG

Product: putative cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-alpha; Cytochrome c oxidase polypeptide I-alpha

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MTAVEPRPVPQLEATRPYPARTGPKGSFLYKMVTTTDPKVLGTMYLVTAMSFFMIGGLMALLMRGELARPGLQFLSPEQF
NQLFTMHGTIMLLFYATAIVFGFANIILPLQIGAPDVAFPRLNAFSYWLYAFGATMATAGFITPGGAADFGWTAYVPLTD
ILHSPGVGTDLWILGLAVSGLGTILGGVNMLTTVVCLRAPGMTMFRMPIFTWNIAVTSVLVLLAFPLLTAALFGLAYDRH
LGGHIYDPATGGILLYQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYATLGIAALSIAVWAHHMYATG
AVLLPYFSFMTFLIAVPTGVKFFNWIGTMWRGQLTFESPMLWSLGFLVTFLFGGLSGVILASPPLDFHVTDSYFVVAHFH
YVLFGTIVFATFAGIYFWFPKITGRMVDERLAKWHFWATFVGFHTTFLVQHWLGAEGMPRRYADYLPSDGFTTLNTISTI
GAFVLGASMLPFIWNIFKSYRYGEVVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERPAFELHYPHMIERMRAEAH
VGWGSGKHGTPQDDDALLAKK

Sequences:

>Translated_581_residues
MTAVEPRPVPQLEATRPYPARTGPKGSFLYKMVTTTDPKVLGTMYLVTAMSFFMIGGLMALLMRGELARPGLQFLSPEQF
NQLFTMHGTIMLLFYATAIVFGFANIILPLQIGAPDVAFPRLNAFSYWLYAFGATMATAGFITPGGAADFGWTAYVPLTD
ILHSPGVGTDLWILGLAVSGLGTILGGVNMLTTVVCLRAPGMTMFRMPIFTWNIAVTSVLVLLAFPLLTAALFGLAYDRH
LGGHIYDPATGGILLYQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYATLGIAALSIAVWAHHMYATG
AVLLPYFSFMTFLIAVPTGVKFFNWIGTMWRGQLTFESPMLWSLGFLVTFLFGGLSGVILASPPLDFHVTDSYFVVAHFH
YVLFGTIVFATFAGIYFWFPKITGRMVDERLAKWHFWATFVGFHTTFLVQHWLGAEGMPRRYADYLPSDGFTTLNTISTI
GAFVLGASMLPFIWNIFKSYRYGEVVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERPAFELHYPHMIERMRAEAH
VGWGSGKHGTPQDDDALLAKK
>Mature_580_residues
TAVEPRPVPQLEATRPYPARTGPKGSFLYKMVTTTDPKVLGTMYLVTAMSFFMIGGLMALLMRGELARPGLQFLSPEQFN
QLFTMHGTIMLLFYATAIVFGFANIILPLQIGAPDVAFPRLNAFSYWLYAFGATMATAGFITPGGAADFGWTAYVPLTDI
LHSPGVGTDLWILGLAVSGLGTILGGVNMLTTVVCLRAPGMTMFRMPIFTWNIAVTSVLVLLAFPLLTAALFGLAYDRHL
GGHIYDPATGGILLYQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYATLGIAALSIAVWAHHMYATGA
VLLPYFSFMTFLIAVPTGVKFFNWIGTMWRGQLTFESPMLWSLGFLVTFLFGGLSGVILASPPLDFHVTDSYFVVAHFHY
VLFGTIVFATFAGIYFWFPKITGRMVDERLAKWHFWATFVGFHTTFLVQHWLGAEGMPRRYADYLPSDGFTTLNTISTIG
AFVLGASMLPFIWNIFKSYRYGEVVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERPAFELHYPHMIERMRAEAHV
GWGSGKHGTPQDDDALLAKK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=42.495126705653, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=529, Percent_Identity=43.8563327032136, Blast_Score=414, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=38.2297551789077, Blast_Score=349, Evalue=9e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=40.251572327044, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=36.0655737704918, Blast_Score=140, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX1A_NOCFA (Q5YRP8)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120507.1
- ProteinModelPortal:   Q5YRP8
- SMR:   Q5YRP8
- GeneID:   3106270
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa42940
- NMPDR:   fig|247156.1.peg.4137
- HOGENOM:   HBG603668
- OMA:   FPRINAF
- BioCyc:   NFAR247156:NFA42940-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR000883
- InterPro:   IPR014241
- Gene3D:   G3DSA:1.20.210.10
- PANTHER:   PTHR10422
- PRINTS:   PR01165
- TIGRFAMs:   TIGR02891

Pfam domain/function: PF00115 COX1; SSF81442 COX1

EC number: =1.9.3.1

Molecular weight: Translated: 64745; Mature: 64613

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50855 COX1; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b37b9b0)-; HASH(0x1b12f5ac)-; HASH(0x1bc1d814)-; HASH(0x1c3b62e8)-; HASH(0x1c022a18)-; HASH(0x1c3b606c)-; HASH(0x1c32b4ac)-; HASH(0x1c3bda00)-; HASH(0x1c17bb38)-; HASH(0x1c390f30)-; HASH(0x1c3b60cc)-; HASH(0x1bfd1430)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVEPRPVPQLEATRPYPARTGPKGSFLYKMVTTTDPKVLGTMYLVTAMSFFMIGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLMRGELARPGLQFLSPEQFNQLFTMHGTIMLLFYATAIVFGFANIILPLQIGAPDVAFP
HHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
RLNAFSYWLYAFGATMATAGFITPGGAADFGWTAYVPLTDILHSPGVGTDLWILGLAVSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHHHHHHHH
LGTILGGVNMLTTVVCLRAPGMTMFRMPIFTWNIAVTSVLVLLAFPLLTAALFGLAYDRH
HHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDPATGGILLYQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYA
CCCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHH
TLGIAALSIAVWAHHMYATGAVLLPYFSFMTFLIAVPTGVKFFNWIGTMWRGQLTFESPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCH
LWSLGFLVTFLFGGLSGVILASPPLDFHVTDSYFVVAHFHYVLFGTIVFATFAGIYFWFP
HHHHHHHHHHHHHCCCCEEEECCCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KITGRMVDERLAKWHFWATFVGFHTTFLVQHWLGAEGMPRRYADYLPSDGFTTLNTISTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHH
GAFVLGASMLPFIWNIFKSYRYGEVVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSE
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPAFELHYPHMIERMRAEAHVGWGSGKHGTPQDDDALLAKK
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
TAVEPRPVPQLEATRPYPARTGPKGSFLYKMVTTTDPKVLGTMYLVTAMSFFMIGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLMRGELARPGLQFLSPEQFNQLFTMHGTIMLLFYATAIVFGFANIILPLQIGAPDVAFP
HHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
RLNAFSYWLYAFGATMATAGFITPGGAADFGWTAYVPLTDILHSPGVGTDLWILGLAVSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHHHHHHHH
LGTILGGVNMLTTVVCLRAPGMTMFRMPIFTWNIAVTSVLVLLAFPLLTAALFGLAYDRH
HHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDPATGGILLYQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYA
CCCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHH
TLGIAALSIAVWAHHMYATGAVLLPYFSFMTFLIAVPTGVKFFNWIGTMWRGQLTFESPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCH
LWSLGFLVTFLFGGLSGVILASPPLDFHVTDSYFVVAHFHYVLFGTIVFATFAGIYFWFP
HHHHHHHHHHHHHCCCCEEEECCCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KITGRMVDERLAKWHFWATFVGFHTTFLVQHWLGAEGMPRRYADYLPSDGFTTLNTISTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHH
GAFVLGASMLPFIWNIFKSYRYGEVVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSE
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPAFELHYPHMIERMRAEAHVGWGSGKHGTPQDDDALLAKK
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA