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The map label for this gene is serB [H]

Identifier: 54026264

GI number: 54026264

Start: 4446621

End: 4447856

Strand: Reverse

Name: serB [H]

Synonym: nfa42930

Alternate gene names: 54026264

Gene position: 4447856-4446621 (Counterclockwise)

Preceding gene: 54026265

Following gene: 54026263

Centisome position: 73.87

GC content: 72.09

Gene sequence:

>1236_bases
TTGGAGCGCACCGACGTGGCCGACACCACCGTTCTCGTGACCGTCACCGGGCCGGACCGGCCGGGCGTGACGTCCGTGCT
GCTCGCGGCCATGTCGCGGCACCAGGTGAGCCTGCTCGACGTGGAGCAGGTCGTCATTCGCGGCAGGCTCACCCTGGGCG
TGCTGATCAGTTGTCCCAGCGACCCCGAGGCGTTGCAGGACGAGCTCGAGGAGGCGATGAACACCGTCGGCATGGCCGTC
GAGGTGGAGGTGGGCGCGGCCATCGGCAGGCAGCCGATGTCCACGCACGCCGTCGTCATCCTCGGCGCGCCGGTCACCGC
GCGGGCGTTCAGCGCCGTCTCGCGGCAGCTGGCCGCGCTGGGCGCCAACATCGACACCATCCGCGGTATCGCCGACTACC
CGGTGACCGGGATGGAGCTGCTGGTCACCGCGATCGACACCGGCAGCGACACCGATTCGCGGCTGCGCACGGCGCTGGCC
GAGGTGGCCGTGGCCGAGGAAGTCGACGTCGCGGTGGAACGGGCGGGCCTGGCCCGGCGCGCCAAGCGGCTGATCGTGTT
CGACGTCGACTCGACCCTGATCCAGGGCGAGGTGATCGAGATGCTGGCCGCGCACGCCGGGGTGGAGGAGCAGGTCCGGC
AGGTCACCGAGGCCGCCATGCGCGGGGAGATCGACTTCGCCGAATCGCTGCGCCAGCGCGTGGCCACGCTCGCGGGCCTG
GACGAGTCGGTCATCGACGAGGTGGCCGAGCGCATCGAGCTGACGCCGGGCGCGCGCACCACCATCCGCACCCTGCGCAG
GCTCGGCTTCCGCTGCGGCGTGGTCTCCGGCGGGTTCCGCCAGGTGATCGAGCCGCTCGCGCACGACCTCGAACTGGATT
TCGTGCAGGCCAACACCCTCGAGATCGTCGACGGCAAGCTCACCGGCCGGGTCGTCGGCGAGATCGTCGACCGCGCGGCC
AAGGCGACCGCGCTGCGCAAGTTCGCCGCCGAGGCGGGCGTGCCGATGGAGCAGACGGTGGCGGTCGGCGACGGCGCCAA
CGACATCGACATGCTCAACGCGGCCGGGCTCGGGGTGGCGTTCAACGCCAAGCCCGCGTTGCGCGAGGTCGCCGACGCGG
CGCTGTCGCACCCGTACCTGGACGCGGTGCTGTTCATCCTCGGCGTCACCCGGGACGAGGTGGAGGCGGCCGACGCGCGC
GATGGCCTGCTGCGCCGGGTGCCGTTGATCGGCTGA

Upstream 100 bases:

>100_bases
CCCGCAGGACGACGACGCGTTGCTGGCGAAGAAGTAACGACGACGACTGTGCACCCGCTGGGCCCCAGCGGGTGCACACT
CGTGTGACGAGCAGAAAGAC

Downstream 100 bases:

>100_bases
GCGGGCCACGGGCCGCCGCCGGGAATGCCCGGCGCCGCCCGCGCCTTGCACACGCCAGGCATCCGCGCGCACCGGATGCA
CCGTGACGCCCGAAGGGGGA

Product: putative phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MERTDVADTTVLVTVTGPDRPGVTSVLLAAMSRHQVSLLDVEQVVIRGRLTLGVLISCPSDPEALQDELEEAMNTVGMAV
EVEVGAAIGRQPMSTHAVVILGAPVTARAFSAVSRQLAALGANIDTIRGIADYPVTGMELLVTAIDTGSDTDSRLRTALA
EVAVAEEVDVAVERAGLARRAKRLIVFDVDSTLIQGEVIEMLAAHAGVEEQVRQVTEAAMRGEIDFAESLRQRVATLAGL
DESVIDEVAERIELTPGARTTIRTLRRLGFRCGVVSGGFRQVIEPLAHDLELDFVQANTLEIVDGKLTGRVVGEIVDRAA
KATALRKFAAEAGVPMEQTVAVGDGANDIDMLNAAGLGVAFNAKPALREVADAALSHPYLDAVLFILGVTRDEVEAADAR
DGLLRRVPLIG

Sequences:

>Translated_411_residues
MERTDVADTTVLVTVTGPDRPGVTSVLLAAMSRHQVSLLDVEQVVIRGRLTLGVLISCPSDPEALQDELEEAMNTVGMAV
EVEVGAAIGRQPMSTHAVVILGAPVTARAFSAVSRQLAALGANIDTIRGIADYPVTGMELLVTAIDTGSDTDSRLRTALA
EVAVAEEVDVAVERAGLARRAKRLIVFDVDSTLIQGEVIEMLAAHAGVEEQVRQVTEAAMRGEIDFAESLRQRVATLAGL
DESVIDEVAERIELTPGARTTIRTLRRLGFRCGVVSGGFRQVIEPLAHDLELDFVQANTLEIVDGKLTGRVVGEIVDRAA
KATALRKFAAEAGVPMEQTVAVGDGANDIDMLNAAGLGVAFNAKPALREVADAALSHPYLDAVLFILGVTRDEVEAADAR
DGLLRRVPLIG
>Mature_411_residues
MERTDVADTTVLVTVTGPDRPGVTSVLLAAMSRHQVSLLDVEQVVIRGRLTLGVLISCPSDPEALQDELEEAMNTVGMAV
EVEVGAAIGRQPMSTHAVVILGAPVTARAFSAVSRQLAALGANIDTIRGIADYPVTGMELLVTAIDTGSDTDSRLRTALA
EVAVAEEVDVAVERAGLARRAKRLIVFDVDSTLIQGEVIEMLAAHAGVEEQVRQVTEAAMRGEIDFAESLRQRVATLAGL
DESVIDEVAERIELTPGARTTIRTLRRLGFRCGVVSGGFRQVIEPLAHDLELDFVQANTLEIVDGKLTGRVVGEIVDRAA
KATALRKFAAEAGVPMEQTVAVGDGANDIDMLNAAGLGVAFNAKPALREVADAALSHPYLDAVLFILGVTRDEVEAADAR
DGLLRRVPLIG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790849, Length=208, Percent_Identity=48.5576923076923, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI115534454, Length=184, Percent_Identity=33.1521739130435, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=184, Percent_Identity=33.1521739130435, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=250, Percent_Identity=43.2, Blast_Score=202, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43518; Mature: 43518

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTDVADTTVLVTVTGPDRPGVTSVLLAAMSRHQVSLLDVEQVVIRGRLTLGVLISCPS
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEECCC
DPEALQDELEEAMNTVGMAVEVEVGAAIGRQPMSTHAVVILGAPVTARAFSAVSRQLAAL
CHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
GANIDTIRGIADYPVTGMELLVTAIDTGSDTDSRLRTALAEVAVAEEVDVAVERAGLARR
CCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRLIVFDVDSTLIQGEVIEMLAAHAGVEEQVRQVTEAAMRGEIDFAESLRQRVATLAGL
CCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
DESVIDEVAERIELTPGARTTIRTLRRLGFRCGVVSGGFRQVIEPLAHDLELDFVQANTL
CHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHCCEEEEEECCEE
EIVDGKLTGRVVGEIVDRAAKATALRKFAAEAGVPMEQTVAVGDGANDIDMLNAAGLGVA
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHCCCCCEE
FNAKPALREVADAALSHPYLDAVLFILGVTRDEVEAADARDGLLRRVPLIG
ECCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERTDVADTTVLVTVTGPDRPGVTSVLLAAMSRHQVSLLDVEQVVIRGRLTLGVLISCPS
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEECCC
DPEALQDELEEAMNTVGMAVEVEVGAAIGRQPMSTHAVVILGAPVTARAFSAVSRQLAAL
CHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
GANIDTIRGIADYPVTGMELLVTAIDTGSDTDSRLRTALAEVAVAEEVDVAVERAGLARR
CCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRLIVFDVDSTLIQGEVIEMLAAHAGVEEQVRQVTEAAMRGEIDFAESLRQRVATLAGL
CCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
DESVIDEVAERIELTPGARTTIRTLRRLGFRCGVVSGGFRQVIEPLAHDLELDFVQANTL
CHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHCCEEEEEECCEE
EIVDGKLTGRVVGEIVDRAAKATALRKFAAEAGVPMEQTVAVGDGANDIDMLNAAGLGVA
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHCCCCCEE
FNAKPALREVADAALSHPYLDAVLFILGVTRDEVEAADARDGLLRRVPLIG
ECCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA