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The map label for this gene is ndh [H]

Identifier: 54026247

GI number: 54026247

Start: 4428447

End: 4429751

Strand: Reverse

Name: ndh [H]

Synonym: nfa42760

Alternate gene names: 54026247

Gene position: 4429751-4428447 (Counterclockwise)

Preceding gene: 54026249

Following gene: 54026246

Centisome position: 73.57

GC content: 68.66

Gene sequence:

>1305_bases
ATGGATAACGTCGCTGTGGTGGAAGCCACGGGAATCGAATACTCGGATGTCGTCATCGTCGGATCGGGGTTCGGCGGGCT
GGCCGCTGCCAAGCAGCTGGCCAAGTCGAACGTCGACTACGTCCTGATCTCAAGCACGCCGGAGCACCTGTTCCAGCCCT
TGCTGTACCAGGTCGCCACGGGGGTGCTGGCCGCCGAGGAGATCGCCCCGCCCATCGCGAAGATCCTGCGCCGCCACGAC
ACCGCCGATGTGCGCCAGGGCACCGTCGTCGCCATCGAACCCGACACCGCGGTGCTGACCTACCGCACCCCCGGCGGCGA
GCTACGCCGCATCCGCTACGGCTCGCTGATCGCCGCGACCGGCGCCTCGCAGTCGTACTTCGGCCGCGACGACTTCGCCG
AGAAGACCTATTCGCTCAAGACCATCGAGGACGCGAAACTGCTGCGCGCCCAGATCGAGCGCGTGTTCACCGAGGCCGCC
ACCGCCGACGAGGCGACCAGGCAGCGGCTGCTCAGCTTCGTGGTGGTCGGCGCGGGCGCGACCGGCGTCGAGGTCGCCGG
GCAGCTCACCGAACTCGCCAAACGCCACTTCCACCAGGAGGTTTCGGTCACCCTGGTCGAAGGCGCCGGTGCCGTGCTGC
CGCCGTTCGGCGGCGGGCTGTCGGAGTACGCGAAGAAGTCGCTCGCCAAGGGCGGCGTCGAGGTGCTGCTGGACACCTTC
GTCACCGACATCGAGCCGGGCAAGGTGACCGTCAAGGACAAGGCGGGCGTGGAGCGCAAGATCGCCGCGGAGACCGTGGT
GTGGTCGGCGGGCGTGCAGGCGGGCGGATTCGCCGAGATCCTCGCCGAGGCCACGGGCGTCGAAACCGACCGCGCCGGGC
GGCTGTTGATCAATCCCGACCTGACCGTGGGCGGCTACGCCGACATCTACGCCATCGGCGACATGACCTCGCTCAACGGC
TACCCGGGCCAGTCGCCGGTGGCGATGCAGGAGGGCAGGCACGCCGCCGACATCATCCGGCGCAAGAAGCAGCCCGGCAC
CCCGTTCGTGTACTGGGACAAGGGCAGCATGGCCGTCATCAGCCGGTTCAGCGCGGTGGCGAAACTCAACGAGCACATCA
CCTTCCGCGGGGTGATCGCCTGGTTCATGTGGCTGGCGGTGCACCTGTTCTACCTGGTCGGCTTCCGCAACCGGTTCGCC
GCGGTGGCGTCGTGGCTGGTGGCGTTCATCGGCACCGGCAGGCCGGGATTCGACGAGGTGGACCGGACCGTCGAGGAACC
CGGACGGGAACGCGTAGCGGCCTGA

Upstream 100 bases:

>100_bases
TTCATGAGCGATCCAGATAATAGTCATCTGAATTATGCGCCCTGACCCCTGAAATATCCGAGTTCCCGATAACGGTTTGT
CATGACAGAAGGAGGCTGTC

Downstream 100 bases:

>100_bases
TTCCGACGCCCCGGTGAACGCCCGGTGTGACCGGCGTCTCGTTCACCGAACCGGCATTCCGCCGACACTTCGAGGTCGCT
CCGGCGCAGTCTGGGGCTGG

Product: putative NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDNVAVVEATGIEYSDVVIVGSGFGGLAAAKQLAKSNVDYVLISSTPEHLFQPLLYQVATGVLAAEEIAPPIAKILRRHD
TADVRQGTVVAIEPDTAVLTYRTPGGELRRIRYGSLIAATGASQSYFGRDDFAEKTYSLKTIEDAKLLRAQIERVFTEAA
TADEATRQRLLSFVVVGAGATGVEVAGQLTELAKRHFHQEVSVTLVEGAGAVLPPFGGGLSEYAKKSLAKGGVEVLLDTF
VTDIEPGKVTVKDKAGVERKIAAETVVWSAGVQAGGFAEILAEATGVETDRAGRLLINPDLTVGGYADIYAIGDMTSLNG
YPGQSPVAMQEGRHAADIIRRKKQPGTPFVYWDKGSMAVISRFSAVAKLNEHITFRGVIAWFMWLAVHLFYLVGFRNRFA
AVASWLVAFIGTGRPGFDEVDRTVEEPGRERVAA

Sequences:

>Translated_434_residues
MDNVAVVEATGIEYSDVVIVGSGFGGLAAAKQLAKSNVDYVLISSTPEHLFQPLLYQVATGVLAAEEIAPPIAKILRRHD
TADVRQGTVVAIEPDTAVLTYRTPGGELRRIRYGSLIAATGASQSYFGRDDFAEKTYSLKTIEDAKLLRAQIERVFTEAA
TADEATRQRLLSFVVVGAGATGVEVAGQLTELAKRHFHQEVSVTLVEGAGAVLPPFGGGLSEYAKKSLAKGGVEVLLDTF
VTDIEPGKVTVKDKAGVERKIAAETVVWSAGVQAGGFAEILAEATGVETDRAGRLLINPDLTVGGYADIYAIGDMTSLNG
YPGQSPVAMQEGRHAADIIRRKKQPGTPFVYWDKGSMAVISRFSAVAKLNEHITFRGVIAWFMWLAVHLFYLVGFRNRFA
AVASWLVAFIGTGRPGFDEVDRTVEEPGRERVAA
>Mature_434_residues
MDNVAVVEATGIEYSDVVIVGSGFGGLAAAKQLAKSNVDYVLISSTPEHLFQPLLYQVATGVLAAEEIAPPIAKILRRHD
TADVRQGTVVAIEPDTAVLTYRTPGGELRRIRYGSLIAATGASQSYFGRDDFAEKTYSLKTIEDAKLLRAQIERVFTEAA
TADEATRQRLLSFVVVGAGATGVEVAGQLTELAKRHFHQEVSVTLVEGAGAVLPPFGGGLSEYAKKSLAKGGVEVLLDTF
VTDIEPGKVTVKDKAGVERKIAAETVVWSAGVQAGGFAEILAEATGVETDRAGRLLINPDLTVGGYADIYAIGDMTSLNG
YPGQSPVAMQEGRHAADIIRRKKQPGTPFVYWDKGSMAVISRFSAVAKLNEHITFRGVIAWFMWLAVHLFYLVGFRNRFA
AVASWLVAFIGTGRPGFDEVDRTVEEPGRERVAA

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=427, Percent_Identity=29.5081967213115, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320118, Length=450, Percent_Identity=26, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6323794, Length=448, Percent_Identity=27.2321428571429, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323515, Length=465, Percent_Identity=26.4516129032258, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46547; Mature: 46547

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNVAVVEATGIEYSDVVIVGSGFGGLAAAKQLAKSNVDYVLISSTPEHLFQPLLYQVAT
CCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
GVLAAEEIAPPIAKILRRHDTADVRQGTVVAIEPDTAVLTYRTPGGELRRIRYGSLIAAT
HHHHHHHHCHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEEECCEEEEC
GASQSYFGRDDFAEKTYSLKTIEDAKLLRAQIERVFTEAATADEATRQRLLSFVVVGAGA
CCCCCCCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGVEVAGQLTELAKRHFHQEVSVTLVEGAGAVLPPFGGGLSEYAKKSLAKGGVEVLLDTF
CHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHH
VTDIEPGKVTVKDKAGVERKIAAETVVWSAGVQAGGFAEILAEATGVETDRAGRLLINPD
HHCCCCCEEEEECCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCC
LTVGGYADIYAIGDMTSLNGYPGQSPVAMQEGRHAADIIRRKKQPGTPFVYWDKGSMAVI
CCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEECCCCHHHH
SRFSAVAKLNEHITFRGVIAWFMWLAVHLFYLVGFRNRFAAVASWLVAFIGTGRPGFDEV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DRTVEEPGRERVAA
HHHHHCCCHHHCCC
>Mature Secondary Structure
MDNVAVVEATGIEYSDVVIVGSGFGGLAAAKQLAKSNVDYVLISSTPEHLFQPLLYQVAT
CCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
GVLAAEEIAPPIAKILRRHDTADVRQGTVVAIEPDTAVLTYRTPGGELRRIRYGSLIAAT
HHHHHHHHCHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEEECCEEEEC
GASQSYFGRDDFAEKTYSLKTIEDAKLLRAQIERVFTEAATADEATRQRLLSFVVVGAGA
CCCCCCCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGVEVAGQLTELAKRHFHQEVSVTLVEGAGAVLPPFGGGLSEYAKKSLAKGGVEVLLDTF
CHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHH
VTDIEPGKVTVKDKAGVERKIAAETVVWSAGVQAGGFAEILAEATGVETDRAGRLLINPD
HHCCCCCEEEEECCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCC
LTVGGYADIYAIGDMTSLNGYPGQSPVAMQEGRHAADIIRRKKQPGTPFVYWDKGSMAVI
CCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEECCCCHHHH
SRFSAVAKLNEHITFRGVIAWFMWLAVHLFYLVGFRNRFAAVASWLVAFIGTGRPGFDEV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DRTVEEPGRERVAA
HHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]