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The map label for this gene is recG [H]

Identifier: 54026165

GI number: 54026165

Start: 4342832

End: 4345099

Strand: Reverse

Name: recG [H]

Synonym: nfa41940

Alternate gene names: 54026165

Gene position: 4345099-4342832 (Counterclockwise)

Preceding gene: 54026166

Following gene: 54026163

Centisome position: 72.16

GC content: 71.16

Gene sequence:

>2268_bases
ATGGCGACACTGAGCGACCGGCTCGACCACATCCTCGGCGCGAAGGCGGCCGACTCGCTGGCCGACGCCTTCGACATGCA
CACCGTCGAGGATCTGCTGCGGCACTACCCGCTCCGGTACGCGACCCAGGGCCAGCCGCTCACCGAGGAGGCGCCCGAGG
ACGGCTCGCACATCACCGTGATCGGCCGGATCGCCAAGACCGAGCTGCGCCCGATGCGCAACCGCCGCGGCTCGCTGCTG
AAGGTGCAGCTCGACACCGGCTCGGGCCGCCCGGTCGATGTCACCTTCTTCAACGGCGACAAGGTCAAGTACGTCGTGAA
ACAGGGCCTGCGGGCGATGATGTCGGGCAATGTCAGCTATTGGCGGCCGGGCAGCTGGAGCCTGAGCCACCCCGGTTACC
TGATCCTGCCCGAGACCGAGGACGAGTCGGTCGGCACGATGACCAGGGTGCGCGGCGGCGGTGATCTGCGCGGATTGGCC
GAGAGCGCGAAAGGCGCCGCCGGAGTGGACGTCTCGTTCATGTCGCGGGAGTTCATCCCGGTCTATCCGGCGACGGCGAA
GGTGCAGAGCTGGGATCTGCTGGCCTGCGTGCGCCAGGTGCTCGAACAACTCGATCCGATCGACGACCCGCTGCCGCAGG
ACATCCGCGAGGAGCGCGGGCTGCTGCCGGTTTCGGACGCGCTGCGGCTGATCCACCTGCCCGAGCACCGCGCCGACATC
GATCGCGCCCGGGACCGGCTGCGCTTCGACGAGGCGCTGGCCCTGCAGCTGGTGCTGGCCGAACGCAGGCACGAGGTGTC
CGGGCGCACCGCGCGCCCGTGCCCGCCGCGGGCCGACGGCATCGCGGCAGCCTTCGCCGAGCGGTTGCCGTTCGAGCTGA
CCGCGGGGCAGCAGAAGGTGATCGGGGAGATCTCCGCCGACCTCGCCCGCACCCATCCCATGCACCGGCTGTTGCAGGGC
GAGGTGGGGTCGGGCAAGACCATCGTCGCGCTGCACGCCATGTTGCAGGTGGTGGACGCGGGGCAGCAGTGCGCGCTGCT
CGCCCCCACCGAAGTCCTCGCCGCCCAGCACTACCGCTCGCTCACCGCGATGCTGGGCGAGCTGGGGACCGCCGGTGAAC
TCGGCGCGGCCGAGCACGCCACCCGGGTCGTGCTGGTGACCGGGTCGATGTCGGCGAGTGCGAAGAAGGCGGCGCTGCTG
GCGGCGGTCACCGGCGAGGCCGGGATCGTGATCGGCACCCATGCGCTGATCCAGGACAACGTCGAGTTCTTCGACCTGGG
CATGGTGATCGTCGACGAACAGCACCGTTTCGGCGTGGAACAGCGCGACGCCCTGCGCGCCAAGGCCAAGGCCGGGGCGA
GTCCGCACCTGCTGGTGATGACCGCGACCCCGATCCCGCGCACGATCGCCATGACCACCCTCGGCGACCTGGAGACCTCC
ACGCTCACCGAACTGCCGCGCGGCCGTTCGCCGATCACGTCCAAGGTGGTGCCGCGCAAACTGCATCCGAACTGGGTGGA
CCGCGCGTGGGAGCGCATCCTCGAGGAGGTCGGGCAGGGCCGCCAGGCGTATGTGGTGTGCTCGCGCATCGGCGACGACG
AGGAGGGCGGCAGGACCGCCAAGGGACGCAAGGCCGCCGAGGAGAAGGAGCCGCCGCCGACGCAGGCGGTGCTCGACGTG
TTCGAGATGCTGCGGCACGGTCCGCTGGCCTCGGTGCGGGTCGGCCTGTTGCACGGCAGGCTGCCCGCCGACGAGAAGGA
CGAGGTGATGCGCGCCTTCCACGAGGGCGCGGTGGACGTGCTGGTCTGCACCACCGTCGTCGAGGTCGGCGTGGACGTGC
CGAACGCGACGGTGATGGTGATCGTCGACGCCGACCGGTTCGGCGTGAGCCAGCTGCACCAGCTGCGCGGGCGCATCGGC
CGCGGCGCGCATCCGGGCCTGTGTCTGCTGGTGACCGACGCGGCGCCGGGTGGGTCGGCGATGACGCGGCTGGAGGCGGT
CGCGGCCACCAACGACGGGTTCGAGCTCGCCGTGCTCGACCTGCGCCAGCGCCGCGAGGGCGATGTGCTCGGCTCGGCCC
AGTCCGGCACCGCGCGCTCCCTGCGGCTGCTGTCGCTGCTGGACGATCTCGAAGTGATCACCACGGCGCAGGACTTGGCG
CGCCGGCTGGTCGAGGCGGACCCAGGCCTGCGCGAGCACCCGGGCCTGGCCGCGATGATGCACGCCGCCGTGGACGCCGA
ACGGCTGGAATACCTCGCCAAGTCCTGA

Upstream 100 bases:

>100_bases
GGGATTCCCCGGCGTCGAGGTGGTGGTGTACCCGGGCGGACAGCGGGGGGATCTGGTGCAGATCGGGGTGGAATGAACGG
TGTGGAATGAGGGCTGACAC

Downstream 100 bases:

>100_bases
GCCGGCCCGCGGCCGGTCGCCGGCTAGCGCGGCAGGCGTGGGTAGGGCAGGTCGGTGCTGGTGTGCTCGCTCACCGTGAG
CGGGCTGCCGATCTGCGGAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MATLSDRLDHILGAKAADSLADAFDMHTVEDLLRHYPLRYATQGQPLTEEAPEDGSHITVIGRIAKTELRPMRNRRGSLL
KVQLDTGSGRPVDVTFFNGDKVKYVVKQGLRAMMSGNVSYWRPGSWSLSHPGYLILPETEDESVGTMTRVRGGGDLRGLA
ESAKGAAGVDVSFMSREFIPVYPATAKVQSWDLLACVRQVLEQLDPIDDPLPQDIREERGLLPVSDALRLIHLPEHRADI
DRARDRLRFDEALALQLVLAERRHEVSGRTARPCPPRADGIAAAFAERLPFELTAGQQKVIGEISADLARTHPMHRLLQG
EVGSGKTIVALHAMLQVVDAGQQCALLAPTEVLAAQHYRSLTAMLGELGTAGELGAAEHATRVVLVTGSMSASAKKAALL
AAVTGEAGIVIGTHALIQDNVEFFDLGMVIVDEQHRFGVEQRDALRAKAKAGASPHLLVMTATPIPRTIAMTTLGDLETS
TLTELPRGRSPITSKVVPRKLHPNWVDRAWERILEEVGQGRQAYVVCSRIGDDEEGGRTAKGRKAAEEKEPPPTQAVLDV
FEMLRHGPLASVRVGLLHGRLPADEKDEVMRAFHEGAVDVLVCTTVVEVGVDVPNATVMVIVDADRFGVSQLHQLRGRIG
RGAHPGLCLLVTDAAPGGSAMTRLEAVAATNDGFELAVLDLRQRREGDVLGSAQSGTARSLRLLSLLDDLEVITTAQDLA
RRLVEADPGLREHPGLAAMMHAAVDAERLEYLAKS

Sequences:

>Translated_755_residues
MATLSDRLDHILGAKAADSLADAFDMHTVEDLLRHYPLRYATQGQPLTEEAPEDGSHITVIGRIAKTELRPMRNRRGSLL
KVQLDTGSGRPVDVTFFNGDKVKYVVKQGLRAMMSGNVSYWRPGSWSLSHPGYLILPETEDESVGTMTRVRGGGDLRGLA
ESAKGAAGVDVSFMSREFIPVYPATAKVQSWDLLACVRQVLEQLDPIDDPLPQDIREERGLLPVSDALRLIHLPEHRADI
DRARDRLRFDEALALQLVLAERRHEVSGRTARPCPPRADGIAAAFAERLPFELTAGQQKVIGEISADLARTHPMHRLLQG
EVGSGKTIVALHAMLQVVDAGQQCALLAPTEVLAAQHYRSLTAMLGELGTAGELGAAEHATRVVLVTGSMSASAKKAALL
AAVTGEAGIVIGTHALIQDNVEFFDLGMVIVDEQHRFGVEQRDALRAKAKAGASPHLLVMTATPIPRTIAMTTLGDLETS
TLTELPRGRSPITSKVVPRKLHPNWVDRAWERILEEVGQGRQAYVVCSRIGDDEEGGRTAKGRKAAEEKEPPPTQAVLDV
FEMLRHGPLASVRVGLLHGRLPADEKDEVMRAFHEGAVDVLVCTTVVEVGVDVPNATVMVIVDADRFGVSQLHQLRGRIG
RGAHPGLCLLVTDAAPGGSAMTRLEAVAATNDGFELAVLDLRQRREGDVLGSAQSGTARSLRLLSLLDDLEVITTAQDLA
RRLVEADPGLREHPGLAAMMHAAVDAERLEYLAKS
>Mature_754_residues
ATLSDRLDHILGAKAADSLADAFDMHTVEDLLRHYPLRYATQGQPLTEEAPEDGSHITVIGRIAKTELRPMRNRRGSLLK
VQLDTGSGRPVDVTFFNGDKVKYVVKQGLRAMMSGNVSYWRPGSWSLSHPGYLILPETEDESVGTMTRVRGGGDLRGLAE
SAKGAAGVDVSFMSREFIPVYPATAKVQSWDLLACVRQVLEQLDPIDDPLPQDIREERGLLPVSDALRLIHLPEHRADID
RARDRLRFDEALALQLVLAERRHEVSGRTARPCPPRADGIAAAFAERLPFELTAGQQKVIGEISADLARTHPMHRLLQGE
VGSGKTIVALHAMLQVVDAGQQCALLAPTEVLAAQHYRSLTAMLGELGTAGELGAAEHATRVVLVTGSMSASAKKAALLA
AVTGEAGIVIGTHALIQDNVEFFDLGMVIVDEQHRFGVEQRDALRAKAKAGASPHLLVMTATPIPRTIAMTTLGDLETST
LTELPRGRSPITSKVVPRKLHPNWVDRAWERILEEVGQGRQAYVVCSRIGDDEEGGRTAKGRKAAEEKEPPPTQAVLDVF
EMLRHGPLASVRVGLLHGRLPADEKDEVMRAFHEGAVDVLVCTTVVEVGVDVPNATVMVIVDADRFGVSQLHQLRGRIGR
GAHPGLCLLVTDAAPGGSAMTRLEAVAATNDGFELAVLDLRQRREGDVLGSAQSGTARSLRLLSLLDDLEVITTAQDLAR
RLVEADPGLREHPGLAAMMHAAVDAERLEYLAKS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=730, Percent_Identity=36.3013698630137, Blast_Score=356, Evalue=3e-99,
Organism=Escherichia coli, GI1787357, Length=435, Percent_Identity=35.4022988505747, Blast_Score=228, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 81679; Mature: 81547

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLSDRLDHILGAKAADSLADAFDMHTVEDLLRHYPLRYATQGQPLTEEAPEDGSHITV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEE
IGRIAKTELRPMRNRRGSLLKVQLDTGSGRPVDVTFFNGDKVKYVVKQGLRAMMSGNVSY
EEEHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCE
WRPGSWSLSHPGYLILPETEDESVGTMTRVRGGGDLRGLAESAKGAAGVDVSFMSREFIP
ECCCCCCCCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHHCCCCCCCCHHHHCCCCEE
VYPATAKVQSWDLLACVRQVLEQLDPIDDPLPQDIREERGLLPVSDALRLIHLPEHRADI
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHEEECCCHHHHH
DRARDRLRFDEALALQLVLAERRHEVSGRTARPCPPRADGIAAAFAERLPFELTAGQQKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHH
IGEISADLARTHPMHRLLQGEVGSGKTIVALHAMLQVVDAGQQCALLAPTEVLAAQHYRS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
LTAMLGELGTAGELGAAEHATRVVLVTGSMSASAKKAALLAAVTGEAGIVIGTHALIQDN
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHEEEEEECCCCCEEEEEHHHHHCC
VEFFDLGMVIVDEQHRFGVEQRDALRAKAKAGASPHLLVMTATPIPRTIAMTTLGDLETS
CCEEEECEEEECCHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEHCCCCCCHH
TLTELPRGRSPITSKVVPRKLHPNWVDRAWERILEEVGQGRQAYVVCSRIGDDEEGGRTA
HHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
KGRKAAEEKEPPPTQAVLDVFEMLRHGPLASVRVGLLHGRLPADEKDEVMRAFHEGAVDV
CCCCCHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHH
LVCTTVVEVGVDVPNATVMVIVDADRFGVSQLHQLRGRIGRGAHPGLCLLVTDAAPGGSA
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
MTRLEAVAATNDGFELAVLDLRQRREGDVLGSAQSGTARSLRLLSLLDDLEVITTAQDLA
HHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLVEADPGLREHPGLAAMMHAAVDAERLEYLAKS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATLSDRLDHILGAKAADSLADAFDMHTVEDLLRHYPLRYATQGQPLTEEAPEDGSHITV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEE
IGRIAKTELRPMRNRRGSLLKVQLDTGSGRPVDVTFFNGDKVKYVVKQGLRAMMSGNVSY
EEEHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCE
WRPGSWSLSHPGYLILPETEDESVGTMTRVRGGGDLRGLAESAKGAAGVDVSFMSREFIP
ECCCCCCCCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHHCCCCCCCCHHHHCCCCEE
VYPATAKVQSWDLLACVRQVLEQLDPIDDPLPQDIREERGLLPVSDALRLIHLPEHRADI
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHEEECCCHHHHH
DRARDRLRFDEALALQLVLAERRHEVSGRTARPCPPRADGIAAAFAERLPFELTAGQQKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHH
IGEISADLARTHPMHRLLQGEVGSGKTIVALHAMLQVVDAGQQCALLAPTEVLAAQHYRS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
LTAMLGELGTAGELGAAEHATRVVLVTGSMSASAKKAALLAAVTGEAGIVIGTHALIQDN
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHEEEEEECCCCCEEEEEHHHHHCC
VEFFDLGMVIVDEQHRFGVEQRDALRAKAKAGASPHLLVMTATPIPRTIAMTTLGDLETS
CCEEEECEEEECCHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEHCCCCCCHH
TLTELPRGRSPITSKVVPRKLHPNWVDRAWERILEEVGQGRQAYVVCSRIGDDEEGGRTA
HHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
KGRKAAEEKEPPPTQAVLDVFEMLRHGPLASVRVGLLHGRLPADEKDEVMRAFHEGAVDV
CCCCCHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHH
LVCTTVVEVGVDVPNATVMVIVDADRFGVSQLHQLRGRIGRGAHPGLCLLVTDAAPGGSA
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
MTRLEAVAATNDGFELAVLDLRQRREGDVLGSAQSGTARSLRLLSLLDDLEVITTAQDLA
HHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLVEADPGLREHPGLAAMMHAAVDAERLEYLAKS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]