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The map label for this gene is rnhB

Identifier: 54026116

GI number: 54026116

Start: 4291410

End: 4292165

Strand: Reverse

Name: rnhB

Synonym: nfa41450

Alternate gene names: 54026116

Gene position: 4292165-4291410 (Counterclockwise)

Preceding gene: 54026117

Following gene: 54026115

Centisome position: 71.28

GC content: 74.07

Gene sequence:

>756_bases
ATGACGGCACGCACGGGGTGGCCGCCGCGCATGGTGATGCGCAAGGCGGGTGGGTTGCGCACGCTGGAGGCGGCGCTGAT
CCGCGGCGGGCTCGGACCCGTCGCGGGCGTGGACGAGGCGGGCCGCGGTCCCTGTGCGGGCCCGCTGGTGGTGGCGGCCT
GCCTGCTGGCGCCCAAGGCCTACGACCGGCTCGCCGGGCTCGACGACTCCAAGAAACTCACCGAGGCCGCCCGCGAGGAG
CTGTACCCGGTGATCACGCGGCTCGCGCTGGCCTGGGAGGTGGTGGTGATCCCGGCCTGGGAGATCGACGCCATCGGCAT
CCACGTCGCCAATATCGAGGGCATGCGCCGTGCGGTCGCGGGCCTGCGACAGCGGCCGGGCTACGTCCTCACCGACGGGT
TCCGGGTGCCCGGCCTCGCGGCGCCCTCCCTGCCGGTCATCGGCGGGGACGCCGCGGCCGCCTGCATCGCCGCCGCGAGC
ATCCTCGCGAAGGTCACCAGGGACCGGATCATGGTCGAGCTGGACAGCCGCCACCCGGGCTACGGTTTCGCCGCCCACAA
GGGCTACAACACCCCCGAACACACCGCGGCGTTGCAGCGGCTCGGCCCGTGCAGCGAACACCGCCGGTCCTGGCGGAATG
TGCGCGAGCGGCTGGGGCTGCGCCCGCTCGATCCCACCGTCGAATACGCCGAGACGGTGCTCGCCGACGGCGTGGCGGAC
AGCCGGGTGGCTGCCGACGCGGCGCATGCGGGATGA

Upstream 100 bases:

>100_bases
CCCATCCGCGCCGAGGACCCCCAGGGCAACTGAGGGGCACGGGCGGATAATTCGCACGGTAGGGATGCACGCAGTGGGGC
AGGCAAGCCGGAGTGGAGCG

Downstream 100 bases:

>100_bases
TGTCGGAATACGACGCACTGCGCCGAGAAGGAGGACGTCCCACCCGATGAGTGCCGAGGACCTCGAGAAGTACGAAACCG
AGATGGAGCTCTCGCTGTAT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTARTGWPPRMVMRKAGGLRTLEAALIRGGLGPVAGVDEAGRGPCAGPLVVAACLLAPKAYDRLAGLDDSKKLTEAAREE
LYPVITRLALAWEVVVIPAWEIDAIGIHVANIEGMRRAVAGLRQRPGYVLTDGFRVPGLAAPSLPVIGGDAAAACIAAAS
ILAKVTRDRIMVELDSRHPGYGFAAHKGYNTPEHTAALQRLGPCSEHRRSWRNVRERLGLRPLDPTVEYAETVLADGVAD
SRVAADAAHAG

Sequences:

>Translated_251_residues
MTARTGWPPRMVMRKAGGLRTLEAALIRGGLGPVAGVDEAGRGPCAGPLVVAACLLAPKAYDRLAGLDDSKKLTEAAREE
LYPVITRLALAWEVVVIPAWEIDAIGIHVANIEGMRRAVAGLRQRPGYVLTDGFRVPGLAAPSLPVIGGDAAAACIAAAS
ILAKVTRDRIMVELDSRHPGYGFAAHKGYNTPEHTAALQRLGPCSEHRRSWRNVRERLGLRPLDPTVEYAETVLADGVAD
SRVAADAAHAG
>Mature_250_residues
TARTGWPPRMVMRKAGGLRTLEAALIRGGLGPVAGVDEAGRGPCAGPLVVAACLLAPKAYDRLAGLDDSKKLTEAAREEL
YPVITRLALAWEVVVIPAWEIDAIGIHVANIEGMRRAVAGLRQRPGYVLTDGFRVPGLAAPSLPVIGGDAAAACIAAASI
LAKVTRDRIMVELDSRHPGYGFAAHKGYNTPEHTAALQRLGPCSEHRRSWRNVRERLGLRPLDPTVEYAETVLADGVADS
RVAADAAHAG

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=187, Percent_Identity=49.7326203208556, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_NOCFA (Q5YS47)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120358.1
- ProteinModelPortal:   Q5YS47
- SMR:   Q5YS47
- GeneID:   3111464
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa41450
- NMPDR:   fig|247156.1.peg.3999
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   NFAR247156:NFA41450-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 26572; Mature: 26441

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTGWPPRMVMRKAGGLRTLEAALIRGGLGPVAGVDEAGRGPCAGPLVVAACLLAPKA
CCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHH
YDRLAGLDDSKKLTEAAREELYPVITRLALAWEVVVIPAWEIDAIGIHVANIEGMRRAVA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEECEEEEEEECHHHHHHHHH
GLRQRPGYVLTDGFRVPGLAAPSLPVIGGDAAAACIAAASILAKVTRDRIMVELDSRHPG
HHHHCCCEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
YGFAAHKGYNTPEHTAALQRLGPCSEHRRSWRNVRERLGLRPLDPTVEYAETVLADGVAD
CCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
SRVAADAAHAG
HHHHHHHHCCC
>Mature Secondary Structure 
TARTGWPPRMVMRKAGGLRTLEAALIRGGLGPVAGVDEAGRGPCAGPLVVAACLLAPKA
CCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHH
YDRLAGLDDSKKLTEAAREELYPVITRLALAWEVVVIPAWEIDAIGIHVANIEGMRRAVA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEECEEEEEEECHHHHHHHHH
GLRQRPGYVLTDGFRVPGLAAPSLPVIGGDAAAACIAAASILAKVTRDRIMVELDSRHPG
HHHHCCCEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
YGFAAHKGYNTPEHTAALQRLGPCSEHRRSWRNVRERLGLRPLDPTVEYAETVLADGVAD
CCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
SRVAADAAHAG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA