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The map label for this gene is lepB [H]

Identifier: 54026117

GI number: 54026117

Start: 4292233

End: 4293009

Strand: Reverse

Name: lepB [H]

Synonym: nfa41460

Alternate gene names: 54026117

Gene position: 4293009-4292233 (Counterclockwise)

Preceding gene: 54026118

Following gene: 54026116

Centisome position: 71.3

GC content: 67.95

Gene sequence:

>777_bases
GTGGCAGACGAAAGTGGGTCGGTGCGGGTGTCCGAATCGGACGACGAGGGGGCGGGCCGCCGCGGGCGGCGCAGGGGTAA
TCGGAAGACGAAACAGCAGCGGCCGTTCTGGCAGGAACTGCCGATTCTGATCGGCATCGCCGCCATCATCGCCGCGCTCG
TGGTCACCTTCATCGGTAGGCCGTATGTGATCCCCTCCCAGTCGATGGAGGAGACGCTGCAGATCGGCGACCGCATCTAC
GTCCAGAAGATCAGCTACTACGCCGGGGACCCGCAGCCCGGTGACGTCGTCGTCTTCGTCGGTCCGCCCTCCTGGAACAC
CCGCTACCAGTCGATCCGCTCGGACAACCCGGTGGTGCGCGGCGTCCAGAACTTCCTCTCCTTCTTCGGGCTCGTCCCGC
CCGACGAGAACGACCTGGTCAAGCGCGTCATCGCGGTCGGCGGGCAGACCGTGCAGTGCTGCGACGCCCAGGGCCGGGTG
ATGGTCGACGGCAAGGCCCTCGACGAACCGTATGTCCAGAACGACTACCGCTGGCTGACCGGCCAGCAGAACGCGAGCTA
CCCGGCCGGGCGGGTGTTCGGGCCGATCAAGGTGCCCGAGGGCCATCTGTGGGTGATGGGGGACAACCGCAACCAGTCCG
CGGATTCCCGCGCGCACGTCGGTGACGAGCTCCAGGGCACCGTGCCGATCGAGAACGTGCGCGGCAAGGCCGTGTTCAAG
ATCTGGCCGCCGACCCGGCTCGGCCCCATCCGCGCCGAGGACCCCCAGGGCAACTGA

Upstream 100 bases:

>100_bases
ATCAAGGAGAAGCGCTGAGCGCTGCCCTTGACCGGGACAACTGATCGTCGACTGGCCCGGCACCGGACGTGAGTCATGGT
GCCGGGCTAGTCTGTTCGGC

Downstream 100 bases:

>100_bases
GGGGCACGGGCGGATAATTCGCACGGTAGGGATGCACGCAGTGGGGCAGGCAAGCCGGAGTGGAGCGATGACGGCACGCA
CGGGGTGGCCGCCGCGCATG

Product: putative peptidase

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MADESGSVRVSESDDEGAGRRGRRRGNRKTKQQRPFWQELPILIGIAAIIAALVVTFIGRPYVIPSQSMEETLQIGDRIY
VQKISYYAGDPQPGDVVVFVGPPSWNTRYQSIRSDNPVVRGVQNFLSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRV
MVDGKALDEPYVQNDYRWLTGQQNASYPAGRVFGPIKVPEGHLWVMGDNRNQSADSRAHVGDELQGTVPIENVRGKAVFK
IWPPTRLGPIRAEDPQGN

Sequences:

>Translated_258_residues
MADESGSVRVSESDDEGAGRRGRRRGNRKTKQQRPFWQELPILIGIAAIIAALVVTFIGRPYVIPSQSMEETLQIGDRIY
VQKISYYAGDPQPGDVVVFVGPPSWNTRYQSIRSDNPVVRGVQNFLSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRV
MVDGKALDEPYVQNDYRWLTGQQNASYPAGRVFGPIKVPEGHLWVMGDNRNQSADSRAHVGDELQGTVPIENVRGKAVFK
IWPPTRLGPIRAEDPQGN
>Mature_257_residues
ADESGSVRVSESDDEGAGRRGRRRGNRKTKQQRPFWQELPILIGIAAIIAALVVTFIGRPYVIPSQSMEETLQIGDRIYV
QKISYYAGDPQPGDVVVFVGPPSWNTRYQSIRSDNPVVRGVQNFLSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRVM
VDGKALDEPYVQNDYRWLTGQQNASYPAGRVFGPIKVPEGHLWVMGDNRNQSADSRAHVGDELQGTVPIENVRGKAVFKI
WPPTRLGPIRAEDPQGN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28559; Mature: 28427

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADESGSVRVSESDDEGAGRRGRRRGNRKTKQQRPFWQELPILIGIAAIIAALVVTFIGR
CCCCCCCEEEECCCCCCCCHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
PYVIPSQSMEETLQIGDRIYVQKISYYAGDPQPGDVVVFVGPPSWNTRYQSIRSDNPVVR
CEECCCHHHHHHHHHCCEEEEEEEHECCCCCCCCCEEEEECCCCCCHHHHHHCCCCHHHH
GVQNFLSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRVMVDGKALDEPYVQNDYRWLT
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEE
GQQNASYPAGRVFGPIKVPEGHLWVMGDNRNQSADSRAHVGDELQGTVPIENVRGKAVFK
CCCCCCCCCCCEECCEECCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEE
IWPPTRLGPIRAEDPQGN
ECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADESGSVRVSESDDEGAGRRGRRRGNRKTKQQRPFWQELPILIGIAAIIAALVVTFIGR
CCCCCCEEEECCCCCCCCHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
PYVIPSQSMEETLQIGDRIYVQKISYYAGDPQPGDVVVFVGPPSWNTRYQSIRSDNPVVR
CEECCCHHHHHHHHHCCEEEEEEEHECCCCCCCCCEEEEECCCCCCHHHHHHCCCCHHHH
GVQNFLSFFGLVPPDENDLVKRVIAVGGQTVQCCDAQGRVMVDGKALDEPYVQNDYRWLT
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEE
GQQNASYPAGRVFGPIKVPEGHLWVMGDNRNQSADSRAHVGDELQGTVPIENVRGKAVFK
CCCCCCCCCCCEECCEECCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEE
IWPPTRLGPIRAEDPQGN
ECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]