Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 54026110

GI number: 54026110

Start: 4285896

End: 4286819

Strand: Reverse

Name: xerC [H]

Synonym: nfa41390

Alternate gene names: 54026110

Gene position: 4286819-4285896 (Counterclockwise)

Preceding gene: 54026111

Following gene: 54026109

Centisome position: 71.2

GC content: 72.51

Gene sequence:

>924_bases
ATGGAGGGTTTGCCGGAAGACCTGACGGCGTTGCTGGCGGAGTACGGGCGACATCTGCGGCTGGGGCAGAATCGCTCCGC
CCACACGGTCCGCGCCTACGTGGGGGATGCCCGGGCGTTGCTGACGCACTTGTACACGCGGTCGCCGGACGCGGCGATCG
GGGAGCTGGACCTGCCGTTGCTGCGGTCCTGGTTGGCCGATCTGGCCGCCGCGGGCGCGGCGCGCACCACGCTGGCGCGC
CGGGCGTCGGCGGTGCGGACGTTCACCGCGTGGCTGACCGGGACGGGTAGGTTGCCGGCTGACCCCGGCCTGCGGCTGGC
CGCGCCCAAGGCGCACCGCACCCTGCCCGCGGTGCTGGCCCGGCAGCAGGCAGTGGCCGCGATGGACGCCGCCGAGTCCG
GTGCCCGGCAAGAGGATCCGATGGCCTTGCGGGACCGGTTGATCGTGGAGATGCTCTACGCCACCGGCATCCGGGTGAGC
GAGCTGTGCGGCCTCGACATCGACGATGTCGATCGTGAGCGCAGGCTGGTGCGGGTGCTGGGCAAGGGCAACAAGGAACG
CTCGGTGCCCTTCGGCGGACCCGCGGATCTGGCCGTGGAACAGTGGCTGCGGCGCGGCAGACCCGCCTTCGCCACCGTCG
AGTCGGGCCGGGCGCTGCTGATCGGGCGGCGGGGGCGACGGCTGGACCAGCGACAGGCGCGGACCGTGGTGCACGAGGTC
GTCTCCGCGATCCCCGGCGCACCCGACCTCGGCCCGCACGGCCTACGCCACAGCGCGGCCACCCACCTGCTCGAAGGCGG
AGCCGACCTGCGCGTGGTGCAGGAACTGCTCGGTCACAGCAGCCTGGCGACCACCCAGCTCTACACCCACGTGTCCATCG
AGCGATTGAAGAAGGTGCACGATCAGGCGCACCCGCGGGCCTGA

Upstream 100 bases:

>100_bases
CCGCGGATGGGTGATTCGATACTCGGACCCGCCCCGGGGTCGGCGGCCGACGGCGGCGCGGGAACTTGTCAACCGCGAGC
GGGCGGGTCACGGTGGGGGA

Downstream 100 bases:

>100_bases
CGAACGCTATTCTGAAACAAGTTCTAGTTTCGGGAGGCGGGCGCATGGCGGTGGAGACAGGCGACGGAGCGGCGCGCACC
CACCTGGTGCTGGGTCAGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEGLPEDLTALLAEYGRHLRLGQNRSAHTVRAYVGDARALLTHLYTRSPDAAIGELDLPLLRSWLADLAAAGAARTTLAR
RASAVRTFTAWLTGTGRLPADPGLRLAAPKAHRTLPAVLARQQAVAAMDAAESGARQEDPMALRDRLIVEMLYATGIRVS
ELCGLDIDDVDRERRLVRVLGKGNKERSVPFGGPADLAVEQWLRRGRPAFATVESGRALLIGRRGRRLDQRQARTVVHEV
VSAIPGAPDLGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVSIERLKKVHDQAHPRA

Sequences:

>Translated_307_residues
MEGLPEDLTALLAEYGRHLRLGQNRSAHTVRAYVGDARALLTHLYTRSPDAAIGELDLPLLRSWLADLAAAGAARTTLAR
RASAVRTFTAWLTGTGRLPADPGLRLAAPKAHRTLPAVLARQQAVAAMDAAESGARQEDPMALRDRLIVEMLYATGIRVS
ELCGLDIDDVDRERRLVRVLGKGNKERSVPFGGPADLAVEQWLRRGRPAFATVESGRALLIGRRGRRLDQRQARTVVHEV
VSAIPGAPDLGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVSIERLKKVHDQAHPRA
>Mature_307_residues
MEGLPEDLTALLAEYGRHLRLGQNRSAHTVRAYVGDARALLTHLYTRSPDAAIGELDLPLLRSWLADLAAAGAARTTLAR
RASAVRTFTAWLTGTGRLPADPGLRLAAPKAHRTLPAVLARQQAVAAMDAAESGARQEDPMALRDRLIVEMLYATGIRVS
ELCGLDIDDVDRERRLVRVLGKGNKERSVPFGGPADLAVEQWLRRGRPAFATVESGRALLIGRRGRRLDQRQARTVVHEV
VSAIPGAPDLGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVSIERLKKVHDQAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=290, Percent_Identity=41.0344827586207, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=36.2126245847176, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1790768, Length=172, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790767, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33346; Mature: 33346

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLPEDLTALLAEYGRHLRLGQNRSAHTVRAYVGDARALLTHLYTRSPDAAIGELDLPL
CCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LRSWLADLAAAGAARTTLARRASAVRTFTAWLTGTGRLPADPGLRLAAPKAHRTLPAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHH
RQQAVAAMDAAESGARQEDPMALRDRLIVEMLYATGIRVSELCGLDIDDVDRERRLVRVL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHH
GKGNKERSVPFGGPADLAVEQWLRRGRPAFATVESGRALLIGRRGRRLDQRQARTVVHEV
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
VSAIPGAPDLGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVSIERLKKVH
HHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DQAHPRA
HHCCCCC
>Mature Secondary Structure
MEGLPEDLTALLAEYGRHLRLGQNRSAHTVRAYVGDARALLTHLYTRSPDAAIGELDLPL
CCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LRSWLADLAAAGAARTTLARRASAVRTFTAWLTGTGRLPADPGLRLAAPKAHRTLPAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHH
RQQAVAAMDAAESGARQEDPMALRDRLIVEMLYATGIRVSELCGLDIDDVDRERRLVRVL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHH
GKGNKERSVPFGGPADLAVEQWLRRGRPAFATVESGRALLIGRRGRRLDQRQARTVVHEV
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
VSAIPGAPDLGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVSIERLKKVH
HHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DQAHPRA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA