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The map label for this gene is hsaB [H]

Identifier: 54026066

GI number: 54026066

Start: 4246866

End: 4247381

Strand: Reverse

Name: hsaB [H]

Synonym: nfa40950

Alternate gene names: 54026066

Gene position: 4247381-4246866 (Counterclockwise)

Preceding gene: 54026067

Following gene: 54026065

Centisome position: 70.54

GC content: 72.09

Gene sequence:

>516_bases
ATGACCGACACCCTCACCGGCACTGACCTGCCGGAGCTCGACCCCACCCTGATGCGCCATGTGCTGGGGCATTTCGCCAC
CGGCGTCGTCGCGATCACCGGAATCGACCCCGAGACCGGGCAACCCACCGGGCTGGCGGCCAACTCGTTCACCTCGGTCT
CGCTCGACCCGCCGCTGATCGCGTTCTGCGTGGCCGCGACGAGCACATCGTGGCCACGGGTGCGCGCGGCGGGGCGGTAC
GTGGTCAACATCCTGGCCGCGGCGCAGGAGCCGGTGTGCCGCCAACTGGCGGCTCGCGGCGCCGACAAGTTCCAGGGCCT
GGACTGGACGCCGTCGCCGCTCGGCGCTCCGGTGCTCGGCGAGTGCCTGGCCTGGATCGAAGCCGAGCCGCAGGCCGAAC
ACGAGGCGGGTGACCACACCATCGTCGTCTCCCGGGTGCGGAGCCTGCACGCCACCGACCGGGACCCGCTGGTGTTCTTC
CGCGGCCGCTACGGCAGTCTCGGCACCCCGCGGTGA

Upstream 100 bases:

>100_bases
CGCCCCGCGGTCGGCGAGGGCACGGCATGAGCCGGCGGTCGACGGGCAGGCCGCGCGACACCCACGCCCGCACGGGCGCC
GCACTCCTGGAAGGTGACCC

Downstream 100 bases:

>100_bases
ATCCGGCGGCACCGGCGGAAAGCTGTGCCGGTCACCGGGAATTCGGCCCGGCGGGGCGCCGCTCCGGTGGCAGGCTCGGG
GCATGAGTACTCCAGTCGAT

Product: putative reductase

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTDTLTGTDLPELDPTLMRHVLGHFATGVVAITGIDPETGQPTGLAANSFTSVSLDPPLIAFCVAATSTSWPRVRAAGRY
VVNILAAAQEPVCRQLAARGADKFQGLDWTPSPLGAPVLGECLAWIEAEPQAEHEAGDHTIVVSRVRSLHATDRDPLVFF
RGRYGSLGTPR

Sequences:

>Translated_171_residues
MTDTLTGTDLPELDPTLMRHVLGHFATGVVAITGIDPETGQPTGLAANSFTSVSLDPPLIAFCVAATSTSWPRVRAAGRY
VVNILAAAQEPVCRQLAARGADKFQGLDWTPSPLGAPVLGECLAWIEAEPQAEHEAGDHTIVVSRVRSLHATDRDPLVFF
RGRYGSLGTPR
>Mature_170_residues
TDTLTGTDLPELDPTLMRHVLGHFATGVVAITGIDPETGQPTGLAANSFTSVSLDPPLIAFCVAATSTSWPRVRAAGRYV
VNILAAAQEPVCRQLAARGADKFQGLDWTPSPLGAPVLGECLAWIEAEPQAEHEAGDHTIVVSRVRSLHATDRDPLVFFR
GRYGSLGTPR

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 18199; Mature: 18068

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTLTGTDLPELDPTLMRHVLGHFATGVVAITGIDPETGQPTGLAANSFTSVSLDPPLI
CCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCEECCCCCHHH
AFCVAATSTSWPRVRAAGRYVVNILAAAQEPVCRQLAARGADKFQGLDWTPSPLGAPVLG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCCCCCCCCCCHHHH
ECLAWIEAEPQAEHEAGDHTIVVSRVRSLHATDRDPLVFFRGRYGSLGTPR
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TDTLTGTDLPELDPTLMRHVLGHFATGVVAITGIDPETGQPTGLAANSFTSVSLDPPLI
CCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCEECCCCCHHH
AFCVAATSTSWPRVRAAGRYVVNILAAAQEPVCRQLAARGADKFQGLDWTPSPLGAPVLG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCCCCCCCCCCHHHH
ECLAWIEAEPQAEHEAGDHTIVVSRVRSLHATDRDPLVFFRGRYGSLGTPR
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA