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The map label for this gene is cobQ

Identifier: 54026059

GI number: 54026059

Start: 4239984

End: 4241546

Strand: Reverse

Name: cobQ

Synonym: nfa40880

Alternate gene names: 54026059

Gene position: 4241546-4239984 (Counterclockwise)

Preceding gene: 54026060

Following gene: 54026058

Centisome position: 70.44

GC content: 74.02

Gene sequence:

>1563_bases
GTGAAGGGCGCGCTGCTGGTCGCGGGCACCACCTCCGACGCGGGAAAGAGCGTGGTGGTGGCCGGGCTGTGCCGGATGCT
GGCGCGCCGTGGCGTGCGGGTGGCGCCGTTCAAGGCGCAGAACATGTCCAACAACTCCGTGGTCACCCTCGACGGCGGGG
AGATCGGCCGCGCCCAGGCGTTGCAGGCCCGCGCGTGCGGGCTCGAACCCAGCGTGCGGTTCAACCCGGTGCTGTTGAAA
CCCGGCAGCGACCGGCGCTCGCAACTGGTGGTGCGCGGTCAGGCCGTCGACACCGTCGGCGCCGCCGACTACTTCCGCCA
CCGCACCGCCCTGCGCGAGGTCGTCGCCGCCGAATTGGCTTCGCTGCGGGCCGAATTCGACGTGGTGCTCTGCGAGGGCG
CCGGTTCGCCCGCGGAGATCAACCTGCGCGCCACCGATCTGGCGAACATGGGGCTGGCCCGCGCCGCGGACCTGCCGGTG
CTCGTCGTCGGCGACATCGACCGGGGCGGCGTGCTGGCCCACCTGTTCGGCACCGTGGCGGTGCTCGAACCCGACGACCA
GCGGTTGATCGCCGGCTTCGTGGTCAACAAGTTCCGCGGCGACGTCGACCTGTTACGGCCCGGGCTCGACCGGCTCGCCG
AACTCACCGGCAGGCCCACTCTCGGCGTCCTGCCGTTTGCCGAGGAGCTGTGGCTGGACGCCGAGGATTCGCTCGGCACC
GTCGCCGACGCGCCGGTCGGCCGGCCGCGCCCGCCGGTGGGGACCGAGTGGCTGACGGTCGCGGCGGTGCGGTTGCCGCG
CATCTCCAACTCCACCGACGTGGAGGCGCTGGCCTGCGAACCCGGCGTCGCGGTGCGCTGGGTGAGCGAGCCCTCCCGGC
TCGCCGACGCCGATCTCGTCGTGGTGCCCGGCAGCAAGTCGACCGTCTCGGATCTGGCGTGGTTGCGTCGCACCGGCCTC
GGCGAGGCGTTACGGGCGCGGGTGACCGCGGGCCGGCCGGTGCTCGCGATCTGCGGCGGGTACCAGATGCTCGGGCGGCG
CATCGTGGACGAGGTCGAGTCCGGGGCGGGCGAGGTCGCCGGGCTGGGCGTGTTCGACCTGGAGACCGAGTTCGCCGCGC
CGAAGGTGCTGCGGCGGGTGACCGGGATGGGCGCGGGAAACCCGGTGCGCGGGTACGAGATCCACCACGGCCGGGTGCGC
CGGTCCGGCGATGCGCCGTGGCTCGGGCTCGTCGACGCACCGGAGGCGGCGGTCGACGGGGGCGAGGACGCCGTGCCGCT
GACGCCGGAAGGGTCCGTGACGGGCGGGGCCTGGGGCACCCACGTGCACGGGCTCTTGGAGAGCGACGGGTTCCGCCGCG
CCTGGTTGCGGGAGGTCGCCGCGCGCGCCGGTCGCCACGGCTTCCAGGTGGCGCCCGACACCTCGGTGGCCGCCGTGCGC
GCCGGACAACTGGACCTGCTCGCCGATCTGGTCGAGAAGCACCTCGATCAGGACGCGCTCGAGCGGATCCTCACCGACGG
TGCGCCCACCGGGCTCCCGGTGCTCACCGTCGGGCAGGCGTAG

Upstream 100 bases:

>100_bases
AAGGACCGCAAGTGGACCGCGCAGTTCGAGCACACGCTGGTCGTCACCGAGACCGGCGCGGAAGTGCTCACCCTGCCGTG
ACCGCGGCCGGACACCGCCG

Downstream 100 bases:

>100_bases
CGGCATCGGTGTGACGCGACCCCTTCGACGCCACCCCGCGCCGGTGTACCGTCTCGACATGGAGTCTCGCCGGATCACGG
TCGGCGACCGGACGTTCACC

Product: cobyric acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQARACGLEPSVRFNPVLLK
PGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELASLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPV
LVVGDIDRGGVLAHLFGTVAVLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT
VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLVVVPGSKSTVSDLAWLRRTGL
GEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVAGLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVR
RSGDAPWLGLVDAPEAAVDGGEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVR
AGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA

Sequences:

>Translated_520_residues
MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQARACGLEPSVRFNPVLLK
PGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELASLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPV
LVVGDIDRGGVLAHLFGTVAVLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT
VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLVVVPGSKSTVSDLAWLRRTGL
GEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVAGLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVR
RSGDAPWLGLVDAPEAAVDGGEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVR
AGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA
>Mature_520_residues
MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQARACGLEPSVRFNPVLLK
PGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELASLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPV
LVVGDIDRGGVLAHLFGTVAVLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT
VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLVVVPGSKSTVSDLAWLRRTGL
GEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVAGLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVR
RSGDAPWLGLVDAPEAAVDGGEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVR
AGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_NOCFA (Q5YSA4)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120301.1
- ProteinModelPortal:   Q5YSA4
- GeneID:   3109380
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa40880
- NMPDR:   fig|247156.1.peg.3946
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- BioCyc:   NFAR247156:NFA40880-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 54608; Mature: 54608

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 338-338 ACT_SITE 443-443

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQA
CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECEECCCCCCCCEEEECCCCCCHHHH
LQARACGLEPSVRFNPVLLKPGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELA
HHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVA
HHHCCEEEEEEECCCCCCEEEEEEHHHHHCCCHHHCCCCEEEEECCCCCCHHHHHHCEEE
VLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCCCC
VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLV
CCCCCCCCCCCCCCCHHHEEEHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCEE
VVPGSKSTVSDLAWLRRTGLGEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVA
EECCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEE
GLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVRRSGDAPWLGLVDAPEAAVDG
ECEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCCEEEEECCCHHHCCC
GEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVR
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEE
AGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC
>Mature Secondary Structure
MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQA
CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECEECCCCCCCCEEEECCCCCCHHHH
LQARACGLEPSVRFNPVLLKPGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELA
HHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVA
HHHCCEEEEEEECCCCCCEEEEEEHHHHHCCCHHHCCCCEEEEECCCCCCHHHHHHCEEE
VLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGT
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCCCC
VADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLV
CCCCCCCCCCCCCCCHHHEEEHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCEE
VVPGSKSTVSDLAWLRRTGLGEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVA
EECCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEE
GLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVRRSGDAPWLGLVDAPEAAVDG
ECEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCCEEEEECCCHHHCCC
GEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVR
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEE
AGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA