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The map label for this gene is dinF [H]

Identifier: 54026033

GI number: 54026033

Start: 4210769

End: 4212118

Strand: Reverse

Name: dinF [H]

Synonym: nfa40630

Alternate gene names: 54026033

Gene position: 4212118-4210769 (Counterclockwise)

Preceding gene: 54026034

Following gene: 54026032

Centisome position: 69.95

GC content: 74.89

Gene sequence:

>1350_bases
GTGAGCGCGGACCCGGCCGCCGCGGGACCCCGGCGCATCCTGGGTCTGGCCCTGCCCACGCTGGGCGTGCTCGTCGCCGA
GCCGCTGTATCTGCTGTTCGATCTGGCCGTGGTGGGCAGGCTGGGCGCGCTGGCGCTGGCCGGGCTCGCGGTCGGCGGGC
TGATCCTGGCGCAGGTGAGCACGCAGCTGACCTTCCTCTCCTACGGCACCACCGCCCGCTCGGCGCGGCGGCACGGCGCA
GGTGACCGGCCCGGCGCGGTGGCCGAGGGCGTCCAGGCCACCTGGCTGGCCGTCGCGGTCGGCGGCCTGATCCTGGTGGT
GATGCAGGCCGCGGCCGGGCCGGTCACCGCCGCCATTTCCGGTGGGGGCGACATCGCCGCCGAGGCGTTGCCGTGGCTGC
GGATCGCCTTGTTCGGGGTGCCGTTGATCCTCATCGCGATGGCGGGTAACGGCTGGCTGCGCGGGGTGCAGGACACCCGG
CGGCCGCTGGTGTTCGTGGTGTGCGGGCTCGGGCTGTCCGCGGTGCTGTGCCCGGTACTGGTCCACGGGCTGCTCGGCGC
GCCGCGTCTGGAACTGGCGGGTTCGGCGGTGGCCAATGTCGCGGGGCAGACGGTGACGGCGGCCCTGTTCGTCACGGCGG
TGGTGCGGGAACGGGTGCCGCTCACCCCGCACTGGTCGGTGATGCGCGCGCAACTCGTGCTCGGGCGGGACCTGATCCTG
CGCAGCCTGTCCTTCCAGGCGTGCTTCGTCTCCGCGGCGGCGGTGGCGGCCCGCTTCGGCGCGGCCTCGGTGGCCGCCCA
CCAACTGGTGCTGCAACTGTGGAGCTTCCTCGCGCTGACCCTCGACGCGCTGGCCATCGCGGCCCAGACCCTGGTCGGCG
CGGCGCTGGGCGGCGGTGACGCCACGGGCGCGCGCCGGCTGGCCGGGCGCATCACGCGGTGGTCGGAGCTGTTCGCGCTG
GCGCTGGCGGCGGTGTTCGCCGCGGGCTACACGGTGATCCCGGCGCTGTTCACCACCGATGCGGCGGTGCTGGAGCGCAC
CCAGGTGGCGTGGTGGTTCTTCGTCGCGCTGATCCCGGTCGCGGGTGTCGTGTTCGCGCTCGACGGGGTGCTGCTCGGCG
CGGGCGACGCCGCCTTCCTGCGCACGGCCACGCTCGCGGCGGCGCTGCTGGGCTTCCTGCCCGCGATCTGGTTGTCGCTG
GCCTTCGACTGGGGGATCGCCGGGATCTGGTCCGGGCTGGCCGCGTTCATGGTGTTGCGGCTGGCGGCGGTGAGCCGGCG
GACGATGTCGGGGAAGTGGGCGACGGTCGGCAGCGAGGTGCCCCACGGCGCTGCCGTGGCCGCCGAGTAG

Upstream 100 bases:

>100_bases
TGGCCACCGCGCTCGGCGGTGGCGGGCACCGGTACGCCGCCGGGTACACCGCCGAGGGCAGCCCCGAGGAGATCGTCGGG
GCGCTGGTGCGGGCGCTCGG

Downstream 100 bases:

>100_bases
CCGGAAAACCCGGCGGCCGCTCCGCGATCACTCGGTAGGATCGCGGCTGTGCAGTGACCGATCCCGCGTGACACACCCAC
GGCGCCGCGAGCCTCGTCGG

Product: putative DNA-damage-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSADPAAAGPRRILGLALPTLGVLVAEPLYLLFDLAVVGRLGALALAGLAVGGLILAQVSTQLTFLSYGTTARSARRHGA
GDRPGAVAEGVQATWLAVAVGGLILVVMQAAAGPVTAAISGGGDIAAEALPWLRIALFGVPLILIAMAGNGWLRGVQDTR
RPLVFVVCGLGLSAVLCPVLVHGLLGAPRLELAGSAVANVAGQTVTAALFVTAVVRERVPLTPHWSVMRAQLVLGRDLIL
RSLSFQACFVSAAAVAARFGAASVAAHQLVLQLWSFLALTLDALAIAAQTLVGAALGGGDATGARRLAGRITRWSELFAL
ALAAVFAAGYTVIPALFTTDAAVLERTQVAWWFFVALIPVAGVVFALDGVLLGAGDAAFLRTATLAAALLGFLPAIWLSL
AFDWGIAGIWSGLAAFMVLRLAAVSRRTMSGKWATVGSEVPHGAAVAAE

Sequences:

>Translated_449_residues
MSADPAAAGPRRILGLALPTLGVLVAEPLYLLFDLAVVGRLGALALAGLAVGGLILAQVSTQLTFLSYGTTARSARRHGA
GDRPGAVAEGVQATWLAVAVGGLILVVMQAAAGPVTAAISGGGDIAAEALPWLRIALFGVPLILIAMAGNGWLRGVQDTR
RPLVFVVCGLGLSAVLCPVLVHGLLGAPRLELAGSAVANVAGQTVTAALFVTAVVRERVPLTPHWSVMRAQLVLGRDLIL
RSLSFQACFVSAAAVAARFGAASVAAHQLVLQLWSFLALTLDALAIAAQTLVGAALGGGDATGARRLAGRITRWSELFAL
ALAAVFAAGYTVIPALFTTDAAVLERTQVAWWFFVALIPVAGVVFALDGVLLGAGDAAFLRTATLAAALLGFLPAIWLSL
AFDWGIAGIWSGLAAFMVLRLAAVSRRTMSGKWATVGSEVPHGAAVAAE
>Mature_448_residues
SADPAAAGPRRILGLALPTLGVLVAEPLYLLFDLAVVGRLGALALAGLAVGGLILAQVSTQLTFLSYGTTARSARRHGAG
DRPGAVAEGVQATWLAVAVGGLILVVMQAAAGPVTAAISGGGDIAAEALPWLRIALFGVPLILIAMAGNGWLRGVQDTRR
PLVFVVCGLGLSAVLCPVLVHGLLGAPRLELAGSAVANVAGQTVTAALFVTAVVRERVPLTPHWSVMRAQLVLGRDLILR
SLSFQACFVSAAAVAARFGAASVAAHQLVLQLWSFLALTLDALAIAAQTLVGAALGGGDATGARRLAGRITRWSELFALA
LAAVFAAGYTVIPALFTTDAAVLERTQVAWWFFVALIPVAGVVFALDGVLLGAGDAAFLRTATLAAALLGFLPAIWLSLA
FDWGIAGIWSGLAAFMVLRLAAVSRRTMSGKWATVGSEVPHGAAVAAE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=434, Percent_Identity=30.184331797235, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 45816; Mature: 45684

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADPAAAGPRRILGLALPTLGVLVAEPLYLLFDLAVVGRLGALALAGLAVGGLILAQVS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLTFLSYGTTARSARRHGAGDRPGAVAEGVQATWLAVAVGGLILVVMQAAAGPVTAAIS
HHHEEEECCCHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGGDIAAEALPWLRIALFGVPLILIAMAGNGWLRGVQDTRRPLVFVVCGLGLSAVLCPVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHCCCCEEHHHHHCHHHHHHHHH
VHGLLGAPRLELAGSAVANVAGQTVTAALFVTAVVRERVPLTPHWSVMRAQLVLGRDLIL
HHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RSLSFQACFVSAAAVAARFGAASVAAHQLVLQLWSFLALTLDALAIAAQTLVGAALGGGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ATGARRLAGRITRWSELFALALAAVFAAGYTVIPALFTTDAAVLERTQVAWWFFVALIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AGVVFALDGVLLGAGDAAFLRTATLAAALLGFLPAIWLSLAFDWGIAGIWSGLAAFMVLR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVSRRTMSGKWATVGSEVPHGAAVAAE
HHHHHHHHCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SADPAAAGPRRILGLALPTLGVLVAEPLYLLFDLAVVGRLGALALAGLAVGGLILAQVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLTFLSYGTTARSARRHGAGDRPGAVAEGVQATWLAVAVGGLILVVMQAAAGPVTAAIS
HHHEEEECCCHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGGDIAAEALPWLRIALFGVPLILIAMAGNGWLRGVQDTRRPLVFVVCGLGLSAVLCPVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHCCCCEEHHHHHCHHHHHHHHH
VHGLLGAPRLELAGSAVANVAGQTVTAALFVTAVVRERVPLTPHWSVMRAQLVLGRDLIL
HHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RSLSFQACFVSAAAVAARFGAASVAAHQLVLQLWSFLALTLDALAIAAQTLVGAALGGGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ATGARRLAGRITRWSELFALALAAVFAAGYTVIPALFTTDAAVLERTQVAWWFFVALIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AGVVFALDGVLLGAGDAAFLRTATLAAALLGFLPAIWLSLAFDWGIAGIWSGLAAFMVLR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVSRRTMSGKWATVGSEVPHGAAVAAE
HHHHHHHHCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]