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The map label for this gene is oxyR [H]

Identifier: 54025758

GI number: 54025758

Start: 4008799

End: 4009707

Strand: Reverse

Name: oxyR [H]

Synonym: nfa37880

Alternate gene names: 54025758

Gene position: 4009707-4008799 (Counterclockwise)

Preceding gene: 54025762

Following gene: 54025757

Centisome position: 66.59

GC content: 71.84

Gene sequence:

>909_bases
GTGAGCGATCAGACTTATCAGCCCACACTGTCGCAGCTGCGTGCGTTCGTGGCGATCGCGGAATACCGCCATTTCGGCAC
GGCCGCAGCGCGTCTGGGTGTGAGCCAACCCACGTTGTCGCAGGCGCTTGCCGCGCTGGAAAACGGGCTCGGTCTGCAGC
TGATCGAACGCAGCACCCGCCGGGTGCTCGTCACCGCCGCGGGCACCCGGTTGCTGCCGCAGGCGATCGCCACGCTCGAG
GCCGCCGATCGGTTCGTCGCCTCCGCGACCGGCGACGGCCTCGGGGGCATGCTGCGGCTGGGCATCATCCCCACCGTCGC
GCCCTACATCCTGCCCGGCCTGCTGCCGCCGCTGCGCGAACGGCTGCCGACGCTGGTGCCGCAGATCATCGAGGACCAGA
CGGCGCGGTTGCTCGAGGGACTGCGCACCGGGGTGCTCGACGCCGCGCTGCTCGCGTTGCCCGCCGACAATCAGGGGCTG
ACCGAGATCCCGCTGTTCACCGAGGAGTTCGTGTTGGTCACCCCGCGCGGGCACGAGCTCGCCGGCCGCACCGACATCGC
GCCCGGCGTGCTGGCGTCGCTGCCGCTGCTGCTGCTCGACGAGGGGCACTGCCTGCGCGACCAGACCCTCGAGCTGTGCC
GCTCGGTGGAGGTCGACCCGCTCGCCGTCGGCGACACCCGGGCGGCCTCGCTGGCGACGGTGGTGCAGTGCGTGGCGGGC
GGGCTGGGCGTCACGCTCATCCCCGAGATGGCGGTCGAGGCCGAAACCGCGCGCGGCACACTGGATGTCGCGCGGTTCTC
CGCACCCGCGCCGGGGCGCACCATCGGCCTGGTGTTCCGTTCGTCGAGTGCGCGGGCGCAGGATTACGAATACCTGGCCG
CGATCATCCGCGCCAACCGGCCGTCATGA

Upstream 100 bases:

>100_bases
GTTCTCCTCGTCCTGGTTGGTGTGGGTCGGTACCTCACAGATGATCTTGCCCACTATTTGCTGAAAGGCAAACGTGATGG
GTGGCACTAGACTGATAGGC

Downstream 100 bases:

>100_bases
GCGCCCTGCCGGGACCGGGCGAACACGCTGCGGGCGAGCCGGATTCGCTGTTCGCCTACGGCACGCTGCGCTTCGCGCCG
GTGCTGGACCGGTTGCTCGG

Product: putative hydrogen peroxide sensing transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSDQTYQPTLSQLRAFVAIAEYRHFGTAAARLGVSQPTLSQALAALENGLGLQLIERSTRRVLVTAAGTRLLPQAIATLE
AADRFVASATGDGLGGMLRLGIIPTVAPYILPGLLPPLRERLPTLVPQIIEDQTARLLEGLRTGVLDAALLALPADNQGL
TEIPLFTEEFVLVTPRGHELAGRTDIAPGVLASLPLLLLDEGHCLRDQTLELCRSVEVDPLAVGDTRAASLATVVQCVAG
GLGVTLIPEMAVEAETARGTLDVARFSAPAPGRTIGLVFRSSSARAQDYEYLAAIIRANRPS

Sequences:

>Translated_302_residues
MSDQTYQPTLSQLRAFVAIAEYRHFGTAAARLGVSQPTLSQALAALENGLGLQLIERSTRRVLVTAAGTRLLPQAIATLE
AADRFVASATGDGLGGMLRLGIIPTVAPYILPGLLPPLRERLPTLVPQIIEDQTARLLEGLRTGVLDAALLALPADNQGL
TEIPLFTEEFVLVTPRGHELAGRTDIAPGVLASLPLLLLDEGHCLRDQTLELCRSVEVDPLAVGDTRAASLATVVQCVAG
GLGVTLIPEMAVEAETARGTLDVARFSAPAPGRTIGLVFRSSSARAQDYEYLAAIIRANRPS
>Mature_301_residues
SDQTYQPTLSQLRAFVAIAEYRHFGTAAARLGVSQPTLSQALAALENGLGLQLIERSTRRVLVTAAGTRLLPQAIATLEA
ADRFVASATGDGLGGMLRLGIIPTVAPYILPGLLPPLRERLPTLVPQIIEDQTARLLEGLRTGVLDAALLALPADNQGLT
EIPLFTEEFVLVTPRGHELAGRTDIAPGVLASLPLLLLDEGHCLRDQTLELCRSVEVDPLAVGDTRAASLATVVQCVAGG
LGVTLIPEMAVEAETARGTLDVARFSAPAPGRTIGLVFRSSSARAQDYEYLAAIIRANRPS

Specific function: Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=41.4965986394558, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787879, Length=245, Percent_Identity=35.1020408163265, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=28.7719298245614, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788887, Length=240, Percent_Identity=31.25, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI157672245, Length=240, Percent_Identity=30.4166666666667, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=29.3650793650794, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787806, Length=272, Percent_Identity=25.3676470588235, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=24.4897959183673, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789204, Length=286, Percent_Identity=27.972027972028, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=297, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=28.90625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=276, Percent_Identity=25.3623188405797, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=181, Percent_Identity=27.0718232044199, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=27.5590551181102, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31922; Mature: 31791

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQTYQPTLSQLRAFVAIAEYRHFGTAAARLGVSQPTLSQALAALENGLGLQLIERSTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCC
RVLVTAAGTRLLPQAIATLEAADRFVASATGDGLGGMLRLGIIPTVAPYILPGLLPPLRE
EEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RLPTLVPQIIEDQTARLLEGLRTGVLDAALLALPADNQGLTEIPLFTEEFVLVTPRGHEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC
AGRTDIAPGVLASLPLLLLDEGHCLRDQTLELCRSVEVDPLAVGDTRAASLATVVQCVAG
CCCCCCCCCHHHHCCHHEECCCCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHC
GLGVTLIPEMAVEAETARGTLDVARFSAPAPGRTIGLVFRSSSARAQDYEYLAAIIRANR
CCCCEEHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
PS
CC
>Mature Secondary Structure 
SDQTYQPTLSQLRAFVAIAEYRHFGTAAARLGVSQPTLSQALAALENGLGLQLIERSTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCC
RVLVTAAGTRLLPQAIATLEAADRFVASATGDGLGGMLRLGIIPTVAPYILPGLLPPLRE
EEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RLPTLVPQIIEDQTARLLEGLRTGVLDAALLALPADNQGLTEIPLFTEEFVLVTPRGHEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC
AGRTDIAPGVLASLPLLLLDEGHCLRDQTLELCRSVEVDPLAVGDTRAASLATVVQCVAG
CCCCCCCCCHHHHCCHHEECCCCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHC
GLGVTLIPEMAVEAETARGTLDVARFSAPAPGRTIGLVFRSSSARAQDYEYLAAIIRANR
CCCCEEHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
PS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9733688 [H]