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The map label for this gene is aldH [H]

Identifier: 54025473

GI number: 54025473

Start: 3714432

End: 3716027

Strand: Reverse

Name: aldH [H]

Synonym: nfa35030

Alternate gene names: 54025473

Gene position: 3716027-3714432 (Counterclockwise)

Preceding gene: 54025474

Following gene: 54025469

Centisome position: 61.72

GC content: 75.0

Gene sequence:

>1596_bases
ATGACCGCCGCGACCACCGAACAGCTGACGGGGGCGAACCTCGTCGGTGCCGCCGACGTGCCCGGCGCCGCCGCGCCGTT
CCGCGCCGTCGATCCGGCGAGCGGGCAGCGGCTCGACCCGGAATACCGGGAGGCCGACGACGCCCAGGTCGACCGCGCCG
CCGAGCTGGCCTGGGCCGCCTTCGACACCTACCGGCACACCGGCCCCGACCGCCGCGCGGCGTTTCTGGAGACCGTCGCC
GCCCAGCTCGACGGCCTCGGTGACGTGCTCGTGCAGCGGGGGATCGCGGAAAGCGGTCTGCCCGAGGCCAGGGTGCGCGG
CGAGATCGCCCGTACCACCGGTCAATTGCGGTTGTTCGCCGAGGTCGTGCGCGAGGGCGGCTGGACCGGTGCGCGGCTGG
ACCGGCCCGACCCGCGGCGCACCCCGCTGCCGAAACCCGATCTGCGCCAGCGCCGTATCCCGCTCGGCCCGGTCGCGGTG
TTCGCCGCGAGCAACTTCCCGCTGGCGTTCTCCGTCGCGGGCGGTGACACCGCCTCCGCGTTGGCCGCCGGCGCGCCGGT
GGTGGTGAAGGCGCACCCCTCCCATCCCGGCACCTCCGAGCTGGTCGGTCGCGCGGTGCGCGCCGCGGTGCGGGCGCACG
ACCTGCCCGAGGGCACGTTCTCGCTGGTCCACGGTGGTCGTGACACCGGTCTGGCGCTGGTGCGGCATCCGCGCATCCGC
GCGGTCGGCTTCACCGGTTCCCGGCAGGCCGGGCTCGCGTTGACCGCGGCCGCCGCCGCGCGACCGGTGCCGATCCCGGT
GTTCGCCGAGATGTCCAGCGTCAATCCGGTCTTCGTCTTACCCGGTGCGCTGGCCGACCGCGGCGCGCAGCTGGGTGCGG
AGTTCGTGGCATCGCTGACCACCGGGGTCGGGCAGCTGTGCACCAGCCCGGGCTTGGTGTTCCTCCCCGACGGGCCGGGT
GCCGACGAGTTCGTCGCGGCCGCCGCGGCGGCGGTGGAGGCCGCCGCGGGCGCACCGATGCTCAACAGCGGTATCGCCTC
GGCCTATGCCGAGGGGGTGCGCAGGCTCGGCGCGGGACCGCAGGTGCGTTCGGTGGCGGTCGGTGCCGCGGCGACCGCGG
CCTGCGGCGGGGTGCCGCACCTGTTCGTCACCACGGCCGAGCATTTCCGGGCCGATCCCGCGTTGCGCGAGGAGGTCTTC
GGCCCGGCCTCGATCGTTGTGCGGGTGGGCGCCCCCGACCGGTTCGCCGAGCTGATCGAGGTGCTCGACGGGCAACTTAC
CGCCACCGTGCACGCGACCACCCAGGACCACGAGCTGGCCCGCCGCCTGCTGCCGCAGCTGGAACTGCTCGCCGGCCGGG
TGCTGTTCAACGGCTGGCCCACCGGCGTGGAGGTCGGTCACGCCGTCGTGCACGGCGGCCCCTTCCCGGCCACCAGCGCG
CCCGCCACCACCTCGGTCGGCAGCCTGGCCATCGAGCGCTTCCTGCGCCCGGTCTCCTACCAGAACATCCCCGACGACCT
CCTGCCCGCCGAGATCCGCGCGGCCAACCCGCTCGGCATCTGGCGCCGCATCGACGGCACCCTCACCAGGGACTGA

Upstream 100 bases:

>100_bases
CGGTGATCGGACGTCCCGCGGGTCCGGTCCGCAGCCCGCTGACCGACCTGGACGACGCCGAACTCGCCGAACTGGCCGAT
CTCGTGAAGAAGGTGAGCTG

Downstream 100 bases:

>100_bases
CCGGTGCCGCCGCGGGTCCCCACCGGGTCCCGCGGCGGGCGGTGGCATGGGAAGGCGCTCTGTGTCAATGGCTTTCGAGA
AGCCGGGTGGGGTGCATGCC

Product: putative aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTAATTEQLTGANLVGAADVPGAAAPFRAVDPASGQRLDPEYREADDAQVDRAAELAWAAFDTYRHTGPDRRAAFLETVA
AQLDGLGDVLVQRGIAESGLPEARVRGEIARTTGQLRLFAEVVREGGWTGARLDRPDPRRTPLPKPDLRQRRIPLGPVAV
FAASNFPLAFSVAGGDTASALAAGAPVVVKAHPSHPGTSELVGRAVRAAVRAHDLPEGTFSLVHGGRDTGLALVRHPRIR
AVGFTGSRQAGLALTAAAAARPVPIPVFAEMSSVNPVFVLPGALADRGAQLGAEFVASLTTGVGQLCTSPGLVFLPDGPG
ADEFVAAAAAAVEAAAGAPMLNSGIASAYAEGVRRLGAGPQVRSVAVGAAATAACGGVPHLFVTTAEHFRADPALREEVF
GPASIVVRVGAPDRFAELIEVLDGQLTATVHATTQDHELARRLLPQLELLAGRVLFNGWPTGVEVGHAVVHGGPFPATSA
PATTSVGSLAIERFLRPVSYQNIPDDLLPAEIRAANPLGIWRRIDGTLTRD

Sequences:

>Translated_531_residues
MTAATTEQLTGANLVGAADVPGAAAPFRAVDPASGQRLDPEYREADDAQVDRAAELAWAAFDTYRHTGPDRRAAFLETVA
AQLDGLGDVLVQRGIAESGLPEARVRGEIARTTGQLRLFAEVVREGGWTGARLDRPDPRRTPLPKPDLRQRRIPLGPVAV
FAASNFPLAFSVAGGDTASALAAGAPVVVKAHPSHPGTSELVGRAVRAAVRAHDLPEGTFSLVHGGRDTGLALVRHPRIR
AVGFTGSRQAGLALTAAAAARPVPIPVFAEMSSVNPVFVLPGALADRGAQLGAEFVASLTTGVGQLCTSPGLVFLPDGPG
ADEFVAAAAAAVEAAAGAPMLNSGIASAYAEGVRRLGAGPQVRSVAVGAAATAACGGVPHLFVTTAEHFRADPALREEVF
GPASIVVRVGAPDRFAELIEVLDGQLTATVHATTQDHELARRLLPQLELLAGRVLFNGWPTGVEVGHAVVHGGPFPATSA
PATTSVGSLAIERFLRPVSYQNIPDDLLPAEIRAANPLGIWRRIDGTLTRD
>Mature_530_residues
TAATTEQLTGANLVGAADVPGAAAPFRAVDPASGQRLDPEYREADDAQVDRAAELAWAAFDTYRHTGPDRRAAFLETVAA
QLDGLGDVLVQRGIAESGLPEARVRGEIARTTGQLRLFAEVVREGGWTGARLDRPDPRRTPLPKPDLRQRRIPLGPVAVF
AASNFPLAFSVAGGDTASALAAGAPVVVKAHPSHPGTSELVGRAVRAAVRAHDLPEGTFSLVHGGRDTGLALVRHPRIRA
VGFTGSRQAGLALTAAAAARPVPIPVFAEMSSVNPVFVLPGALADRGAQLGAEFVASLTTGVGQLCTSPGLVFLPDGPGA
DEFVAAAAAAVEAAAGAPMLNSGIASAYAEGVRRLGAGPQVRSVAVGAAATAACGGVPHLFVTTAEHFRADPALREEVFG
PASIVVRVGAPDRFAELIEVLDGQLTATVHATTQDHELARRLLPQLELLAGRVLFNGWPTGVEVGHAVVHGGPFPATSAP
ATTSVGSLAIERFLRPVSYQNIPDDLLPAEIRAANPLGIWRRIDGTLTRD

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=327, Percent_Identity=25.3822629969419, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081896, Length=450, Percent_Identity=28.4444444444444, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081926, Length=452, Percent_Identity=25.8849557522124, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788042, Length=305, Percent_Identity=29.8360655737705, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786504, Length=329, Percent_Identity=29.1793313069909, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787558, Length=456, Percent_Identity=26.9736842105263, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=431, Percent_Identity=25.9860788863109, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=448, Percent_Identity=22.9910714285714, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25143874, Length=448, Percent_Identity=22.9910714285714, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=452, Percent_Identity=25.2212389380531, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562198, Length=457, Percent_Identity=25.164113785558, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995613, Length=295, Percent_Identity=27.4576271186441, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995606, Length=295, Percent_Identity=27.4576271186441, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115534176, Length=199, Percent_Identity=32.6633165829146, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319478, Length=303, Percent_Identity=25.4125412541254, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281362580, Length=321, Percent_Identity=27.7258566978193, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI62472918, Length=321, Percent_Identity=27.7258566978193, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI62472926, Length=321, Percent_Identity=27.7258566978193, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI62472936, Length=321, Percent_Identity=27.7258566978193, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21356737, Length=321, Percent_Identity=27.7258566978193, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54940; Mature: 54809

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATTEQLTGANLVGAADVPGAAAPFRAVDPASGQRLDPEYREADDAQVDRAAELAWAA
CCCCCCHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
FDTYRHTGPDRRAAFLETVAAQLDGLGDVLVQRGIAESGLPEARVRGEIARTTGQLRLFA
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHH
EVVREGGWTGARLDRPDPRRTPLPKPDLRQRRIPLGPVAVFAASNFPLAFSVAGGDTASA
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCEEEEECCCCHHHH
LAAGAPVVVKAHPSHPGTSELVGRAVRAAVRAHDLPEGTFSLVHGGRDTGLALVRHPRIR
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCCEEEEECCCEE
AVGFTGSRQAGLALTAAAAARPVPIPVFAEMSSVNPVFVLPGALADRGAQLGAEFVASLT
EEECCCCCCCCEEEEHHHCCCCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TGVGQLCTSPGLVFLPDGPGADEFVAAAAAAVEAAAGAPMLNSGIASAYAEGVRRLGAGP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
QVRSVAVGAAATAACGGVPHLFVTTAEHFRADPALREEVFGPASIVVRVGAPDRFAELIE
CHHHEECCHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHHCCCEEEEEEECCCHHHHHHHH
VLDGQLTATVHATTQDHELARRLLPQLELLAGRVLFNGWPTGVEVGHAVVHGGPFPATSA
HHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCCCCCC
PATTSVGSLAIERFLRPVSYQNIPDDLLPAEIRAANPLGIWRRIDGTLTRD
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAATTEQLTGANLVGAADVPGAAAPFRAVDPASGQRLDPEYREADDAQVDRAAELAWAA
CCCCCHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
FDTYRHTGPDRRAAFLETVAAQLDGLGDVLVQRGIAESGLPEARVRGEIARTTGQLRLFA
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHH
EVVREGGWTGARLDRPDPRRTPLPKPDLRQRRIPLGPVAVFAASNFPLAFSVAGGDTASA
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCEEEEECCCCHHHH
LAAGAPVVVKAHPSHPGTSELVGRAVRAAVRAHDLPEGTFSLVHGGRDTGLALVRHPRIR
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCCEEEEECCCEE
AVGFTGSRQAGLALTAAAAARPVPIPVFAEMSSVNPVFVLPGALADRGAQLGAEFVASLT
EEECCCCCCCCEEEEHHHCCCCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TGVGQLCTSPGLVFLPDGPGADEFVAAAAAAVEAAAGAPMLNSGIASAYAEGVRRLGAGP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
QVRSVAVGAAATAACGGVPHLFVTTAEHFRADPALREEVFGPASIVVRVGAPDRFAELIE
CHHHEECCHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHHCCCEEEEEEECCCHHHHHHHH
VLDGQLTATVHATTQDHELARRLLPQLELLAGRVLFNGWPTGVEVGHAVVHGGPFPATSA
HHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCCCCCC
PATTSVGSLAIERFLRPVSYQNIPDDLLPAEIRAANPLGIWRRIDGTLTRD
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]