Click here to switch to the map view.

The map label for this gene is argK [C]

Identifier: 54025435

GI number: 54025435

Start: 3672926

End: 3673975

Strand: Reverse

Name: argK [C]

Synonym: nfa34650

Alternate gene names: 54025435

Gene position: 3673975-3672926 (Counterclockwise)

Preceding gene: 54025436

Following gene: 54025432

Centisome position: 61.02

GC content: 68.57

Gene sequence:

>1050_bases
ATGAGCGACCCGGGTTCCGCCGCGCCCACCCGGGCGCGGCGGAAGATCGACGTAGACGAACTCGCCGCCGCCGTCCGGCG
CAACGACCGAGCGGCCCTGGCACGGGCGATCACCCTGGTCGAATCGACCAGATCCGATCACCGGGCCCTCGCGCAACAGT
TGCTGCTGCGCCTCACCCCCGAAGACGGTGATTCGGCGACCGCCGTGGTCTCCAACCGAGTCGGCATCACCGGTGTGCCC
GGCGTCGGCAAGTCGACCTTCATCGACGCGCTCGGCATGTACCTGATCGGGAAGGGACACAAGGTCGCCGTGCTCGCGGT
CGACCCGTCGTCCACCCGGACCGGTGGTTCGATCCTCGGCGACAAGACGCGCATGGCCCGATTGTCGGTGGAGCCCAACG
CCTTCATCCGGCCGTCGCCGACCGCGGGCACCCTCGGCGGCGTCGCCAAGGCCACCCGGGAGACCATCGTCCTGCTCGAA
GCCGCCGGCTACGACGTGATCCTGGTCGAGACCGTCGGTGTTGGACAGTCCGAGGTGACGGTCGCGAACATGGTCGACGT
GTTCTGCTTCCTCACATTGGCGCGCACCGGCGACCAGTTGCAGGGCATCAAGAAGGGTGTGCTGGAACTGGCCGAGATCG
TGGCCGTCAACAAGGCCGACGGCAAGCACGCGATCGAGGCCAAGTCGGCCGCCCGCGAACTGGCCGGCGCACTGCGCCTG
ATCCACCCGCGCGACGCACTCTGGCGCCCCCCGGTCCTCACCATGAGCGGCCTGGAAGGCACCGGCCTGGACGAGTTCTG
GGAAACCGTGCTCAAACACCGCCGGGTACTCACCGACGCGGGCGCCTTCGACGAGAAACGCCGCAGGCAGTTGATCGACT
GGACCTGGACGATGGTGCACGACCAATTGCTGCGGCGGCTGGCGGAAGCACCGGAGGTCAAGGCGATTCGCGCGGACGTG
GAGCGGGAAGTGCGCGAGGGGACGCTCACCCCTGCTCTGGCGGCCGAGCGCCTGCTCGACGCCTTCGATTCCTCAGCGGT
GCGACGTTAG

Upstream 100 bases:

>100_bases
CGATCTTCCCGCCCGGCACCGTCATCGCCGACGCCGCCATCGACCTGCTGCGCAAGCTCGCCGGCGAGCTGGGTCACGAA
CTGGAGGGTTCCGCGGCGGA

Downstream 100 bases:

>100_bases
ACCCTGGCGGCCGCCGACCACAGACGTGGACGGCGGCCGCTTCGCGTTCCGGCACCGCGCAAGCCGTGCTCGCCGCCCTG
GACGCCGCAGAAGTCGATGT

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSDPGSAAPTRARRKIDVDELAAAVRRNDRAALARAITLVESTRSDHRALAQQLLLRLTPEDGDSATAVVSNRVGITGVP
GVGKSTFIDALGMYLIGKGHKVAVLAVDPSSTRTGGSILGDKTRMARLSVEPNAFIRPSPTAGTLGGVAKATRETIVLLE
AAGYDVILVETVGVGQSEVTVANMVDVFCFLTLARTGDQLQGIKKGVLELAEIVAVNKADGKHAIEAKSAARELAGALRL
IHPRDALWRPPVLTMSGLEGTGLDEFWETVLKHRRVLTDAGAFDEKRRRQLIDWTWTMVHDQLLRRLAEAPEVKAIRADV
EREVREGTLTPALAAERLLDAFDSSAVRR

Sequences:

>Translated_349_residues
MSDPGSAAPTRARRKIDVDELAAAVRRNDRAALARAITLVESTRSDHRALAQQLLLRLTPEDGDSATAVVSNRVGITGVP
GVGKSTFIDALGMYLIGKGHKVAVLAVDPSSTRTGGSILGDKTRMARLSVEPNAFIRPSPTAGTLGGVAKATRETIVLLE
AAGYDVILVETVGVGQSEVTVANMVDVFCFLTLARTGDQLQGIKKGVLELAEIVAVNKADGKHAIEAKSAARELAGALRL
IHPRDALWRPPVLTMSGLEGTGLDEFWETVLKHRRVLTDAGAFDEKRRRQLIDWTWTMVHDQLLRRLAEAPEVKAIRADV
EREVREGTLTPALAAERLLDAFDSSAVRR
>Mature_348_residues
SDPGSAAPTRARRKIDVDELAAAVRRNDRAALARAITLVESTRSDHRALAQQLLLRLTPEDGDSATAVVSNRVGITGVPG
VGKSTFIDALGMYLIGKGHKVAVLAVDPSSTRTGGSILGDKTRMARLSVEPNAFIRPSPTAGTLGGVAKATRETIVLLEA
AGYDVILVETVGVGQSEVTVANMVDVFCFLTLARTGDQLQGIKKGVLELAEIVAVNKADGKHAIEAKSAARELAGALRLI
HPRDALWRPPVLTMSGLEGTGLDEFWETVLKHRRVLTDAGAFDEKRRRQLIDWTWTMVHDQLLRRLAEAPEVKAIRADVE
REVREGTLTPALAAERLLDAFDSSAVRR

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=331, Percent_Identity=45.9214501510574, Blast_Score=292, Evalue=4e-79,
Organism=Escherichia coli, GI1789285, Length=314, Percent_Identity=45.2229299363057, Blast_Score=261, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71994271, Length=338, Percent_Identity=40.8284023668639, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=271, Percent_Identity=42.4354243542435, Blast_Score=246, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 37585; Mature: 37453

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPGSAAPTRARRKIDVDELAAAVRRNDRAALARAITLVESTRSDHRALAQQLLLRLTP
CCCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
EDGDSATAVVSNRVGITGVPGVGKSTFIDALGMYLIGKGHKVAVLAVDPSSTRTGGSILG
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCC
DKTRMARLSVEPNAFIRPSPTAGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVT
CCHHEEEEEECCCCEECCCCCCCCHHHHHHHHHHEEEEEEECCCCEEEEEEECCCCCHHH
VANMVDVFCFLTLARTGDQLQGIKKGVLELAEIVAVNKADGKHAIEAKSAARELAGALRL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IHPRDALWRPPVLTMSGLEGTGLDEFWETVLKHRRVLTDAGAFDEKRRRQLIDWTWTMVH
CCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DQLLRRLAEAPEVKAIRADVEREVREGTLTPALAAERLLDAFDSSAVRR
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDPGSAAPTRARRKIDVDELAAAVRRNDRAALARAITLVESTRSDHRALAQQLLLRLTP
CCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
EDGDSATAVVSNRVGITGVPGVGKSTFIDALGMYLIGKGHKVAVLAVDPSSTRTGGSILG
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCC
DKTRMARLSVEPNAFIRPSPTAGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVT
CCHHEEEEEECCCCEECCCCCCCCHHHHHHHHHHEEEEEEECCCCEEEEEEECCCCCHHH
VANMVDVFCFLTLARTGDQLQGIKKGVLELAEIVAVNKADGKHAIEAKSAARELAGALRL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IHPRDALWRPPVLTMSGLEGTGLDEFWETVLKHRRVLTDAGAFDEKRRRQLIDWTWTMVH
CCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DQLLRRLAEAPEVKAIRADVEREVREGTLTPALAAERLLDAFDSSAVRR
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]