BacMap

Definition	Nocardia farcinica IFM 10152 chromosome, complete genome.
Accession	NC_006361
Length	6,021,225

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The map label for this gene is ephD [H]

Identifier: 54025420

GI number: 54025420

Start: 3656110

End: 3657057

Strand: Reverse

Name: ephD [H]

Synonym: nfa34500

Alternate gene names: 54025420

Gene position: 3657057-3656110 (Counterclockwise)

Preceding gene: 54025421

Following gene: 54025418

Centisome position: 60.74

GC content: 74.89

Gene sequence:

>948_bases
ATGAAACTGCCAGGGCTGCGCGGACTGCTCGCCGCCGTCCCGTTCGCCGCGGTCTCCGGCCCGCCGATCTTCGACCTGGA
GGGACGGGTCGCGCTGGTCACCGGCGCGGGCACCGGCATCGGCCGGGAACTGGCCCGGCTGCTCGCCGCGCGCGGCGCCC
ACGTGGCCGTCGTCGACATCGACGCCGCCGCGGCCGAATCCGCGGCCCGTGATCTGCGCATCCGCGGGTACGCCGTCGCC
GCCGATGTGCGCGACCGAGCGGCCATGCGCGCGGCCGTCGCCCGGGTGCGCGAACACTTCGGCCGCATCGATGTGGTGGT
CGCCAATGCCGGGGTGGTGCCCGAGCCCGCCACGATCCGCACGATGGACCCCGCCGACTTCGACCGTGTCGTCGCGGTGA
ATCTCACCGGCGTGTTCAACACCGTGCACCCCGCGCTGGACGACATCGTCGCCACCGGCGGCCACGTGGTGGTGGTCTCC
TCGGCCGCGGCGTTCGCCCCCGGCATGGCCGGCTCGCCGTACATGACCACCAAGGCCGCGGTCGAACAGTTCGGCCGGGC
CCTGCGGGTGGAGCTGGCCGGGCTCGGCGCCAGCGCGGGCGTGGCCTACCTGGGCATCGTGGAGACCGCGATGACCCGGC
ATACCCTCGACGAGGACGAGCTCGGCCGCGAGGTGGGCGGCCTGTTGCCCTGGCCGCTGGACCAGCGCATCACCGCCCGC
GAGGCCGCCGTCTCCATCGCCGACGGCATCCTGCGCCGCGCCCCCCGCACCATCGCCCCCCGCCAGTGGGAGGCCTACGC
CCTGCTGCGCGGCGTCGTCAACGTGGTCCTCGACGACCGGCTGGCCCGCGACGAGCGCGTCCGGTCCCTCATCCGCCGGG
TCGAGGAACGCCTCGCCGGGCGAGACGGACAGCCCGTGGACGCGCCGGTGACAAGCGCGCCGAGATAG

Upstream 100 bases:

>100_bases
CCGCCGACGGCGCCAACTCCGGTCTGTACCCGAACTGGAGCTTCGAATACGCTCGCCGCACACGGCATTTCGACGCCGAC
TCGTACGAGATGAGGACCCG

Downstream 100 bases:

>100_bases
CCGCACCGAACCCGAGCACGCCGTCGCGGCAGGCACCCTGGTCGGCATCGGGCCGCTGTGCCCACGCCCGAGCACAGCAT
GCTCAGATTCAGGAAGGACG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKLPGLRGLLAAVPFAAVSGPPIFDLEGRVALVTGAGTGIGRELARLLAARGAHVAVVDIDAAAAESAARDLRIRGYAVA
ADVRDRAAMRAAVARVREHFGRIDVVVANAGVVPEPATIRTMDPADFDRVVAVNLTGVFNTVHPALDDIVATGGHVVVVS
SAAAFAPGMAGSPYMTTKAAVEQFGRALRVELAGLGASAGVAYLGIVETAMTRHTLDEDELGREVGGLLPWPLDQRITAR
EAAVSIADGILRRAPRTIAPRQWEAYALLRGVVNVVLDDRLARDERVRSLIRRVEERLAGRDGQPVDAPVTSAPR

Sequences:

>Translated_315_residues
MKLPGLRGLLAAVPFAAVSGPPIFDLEGRVALVTGAGTGIGRELARLLAARGAHVAVVDIDAAAAESAARDLRIRGYAVA
ADVRDRAAMRAAVARVREHFGRIDVVVANAGVVPEPATIRTMDPADFDRVVAVNLTGVFNTVHPALDDIVATGGHVVVVS
SAAAFAPGMAGSPYMTTKAAVEQFGRALRVELAGLGASAGVAYLGIVETAMTRHTLDEDELGREVGGLLPWPLDQRITAR
EAAVSIADGILRRAPRTIAPRQWEAYALLRGVVNVVLDDRLARDERVRSLIRRVEERLAGRDGQPVDAPVTSAPR
>Mature_315_residues
MKLPGLRGLLAAVPFAAVSGPPIFDLEGRVALVTGAGTGIGRELARLLAARGAHVAVVDIDAAAAESAARDLRIRGYAVA
ADVRDRAAMRAAVARVREHFGRIDVVVANAGVVPEPATIRTMDPADFDRVVAVNLTGVFNTVHPALDDIVATGGHVVVVS
SAAAFAPGMAGSPYMTTKAAVEQFGRALRVELAGLGASAGVAYLGIVETAMTRHTLDEDELGREVGGLLPWPLDQRITAR
EAAVSIADGILRRAPRTIAPRQWEAYALLRGVVNVVLDDRLARDERVRSLIRRVEERLAGRDGQPVDAPVTSAPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=30.8056872037915, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=32.1637426900585, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI210032110, Length=273, Percent_Identity=24.9084249084249, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI15277342, Length=200, Percent_Identity=32, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=204, Percent_Identity=30.8823529411765, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.9644670050761, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=30.9644670050761, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4504505, Length=183, Percent_Identity=32.2404371584699, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=198, Percent_Identity=29.2929292929293, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=176, Percent_Identity=30.1136363636364, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI126723191, Length=177, Percent_Identity=32.2033898305085, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=26.9607843137255, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19743808, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI186928839, Length=212, Percent_Identity=30.6603773584906, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI83715985, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4758504, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI225579078, Length=216, Percent_Identity=28.2407407407407, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=37.1134020618557, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787335, Length=200, Percent_Identity=29.5, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790717, Length=203, Percent_Identity=33.9901477832512, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789057, Length=247, Percent_Identity=28.7449392712551, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=200, Percent_Identity=30, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787905, Length=144, Percent_Identity=32.6388888888889, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=168, Percent_Identity=29.7619047619048, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=176, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI2367175, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=172, Percent_Identity=26.1627906976744, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=175, Percent_Identity=30.8571428571429, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=181, Percent_Identity=32.5966850828729, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=184, Percent_Identity=30.9782608695652, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=175, Percent_Identity=27.4285714285714, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=174, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=174, Percent_Identity=28.1609195402299, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=28.8557213930348, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=194, Percent_Identity=30.9278350515464, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=176, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=197, Percent_Identity=29.4416243654822, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=27.7227722772277, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=189, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=235, Percent_Identity=32.7659574468085, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=214, Percent_Identity=34.1121495327103, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21355631, Length=267, Percent_Identity=27.7153558052434, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=33.5260115606936, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=31.2820512820513, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24639444, Length=190, Percent_Identity=32.1052631578947, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=30.2564102564103, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640492, Length=177, Percent_Identity=29.3785310734463, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571526, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45554248, Length=208, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640117, Length=208, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=30.6532663316583, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=171, Percent_Identity=29.8245614035088, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=177, Percent_Identity=29.9435028248588, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331218, Length=177, Percent_Identity=29.9435028248588, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33139; Mature: 33139

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPGLRGLLAAVPFAAVSGPPIFDLEGRVALVTGAGTGIGRELARLLAARGAHVAVVDI
CCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
DAAAAESAARDLRIRGYAVAADVRDRAAMRAAVARVREHFGRIDVVVANAGVVPEPATIR
CHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEE
TMDPADFDRVVAVNLTGVFNTVHPALDDIVATGGHVVVVSSAAAFAPGMAGSPYMTTKAA
ECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCHHHHHH
VEQFGRALRVELAGLGASAGVAYLGIVETAMTRHTLDEDELGREVGGLLPWPLDQRITAR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHH
EAAVSIADGILRRAPRTIAPRQWEAYALLRGVVNVVLDDRLARDERVRSLIRRVEERLAG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDGQPVDAPVTSAPR
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLPGLRGLLAAVPFAAVSGPPIFDLEGRVALVTGAGTGIGRELARLLAARGAHVAVVDI
CCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
DAAAAESAARDLRIRGYAVAADVRDRAAMRAAVARVREHFGRIDVVVANAGVVPEPATIR
CHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEE
TMDPADFDRVVAVNLTGVFNTVHPALDDIVATGGHVVVVSSAAAFAPGMAGSPYMTTKAA
ECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCHHHHHH
VEQFGRALRVELAGLGASAGVAYLGIVETAMTRHTLDEDELGREVGGLLPWPLDQRITAR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHH
EAAVSIADGILRRAPRTIAPRQWEAYALLRGVVNVVLDDRLARDERVRSLIRRVEERLAG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDGQPVDAPVTSAPR
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]