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The map label for this gene is 54025421

Identifier: 54025421

GI number: 54025421

Start: 3657054

End: 3658562

Strand: Reverse

Name: 54025421

Synonym: nfa34510

Alternate gene names: NA

Gene position: 3658562-3657054 (Counterclockwise)

Preceding gene: 54025422

Following gene: 54025420

Centisome position: 60.76

GC content: 69.78

Gene sequence:

>1509_bases
GTGAAGGGGCACCCGCCCCGGGAAGGAGTCGCCGCCGTGGCGACCGACAACACTGCCGCGCACGTCCCCGTGGTGATCAT
CGGGGCGGGCATCGCGGGCATCGCCCTCGGCGTCGAACTGCGCGCCGCGGGCCTCACCGACTTCGTCGTCCTGGAACGCG
CCGAGGGCCTCGGCGGCACCTGGCGGGCCAACACCTATCCCGGCTGCGCCTGCGACGTGCCCTCGCAGCTGTACTCGTAT
TCCTTTGCGCCCAACCCGGACTGGTCACGCACCTACGGCACCCAGCCGGAGATCCTCGGCTACCTCGAGCGTGTCGCCAC
CGAACACGGCGTCGTGGCGCACATGCGGTTCGGCACCGAGTTGCGCGACGCGCGCTGGGACGAGGACGCCGAGGTCTGGC
GCGTGTCGACCAGCCGCGGCGACTACACCGCGGGCGTGCTGATCTCCGCGGTCGGGCCGTTCAGCGAGGCCAGCATCCCC
GACCTGCCGGGCCGGGCGAGCTTCGCCGGCACCCAGTTCCATTCGCTGCACTGGGATCACGAGCACGACCTGCGCGGTGA
GCGGGTCGCGGTGATCGGCACCGGCGCCTCGGCGGTGCAGTTCATCCCGGAGATCCAGCCACTGGTCGGGCAGCTGACGG
TATTCCAGCGGTCGGCGCCGTGGATCGTGTCGCGGCTGGATCGCAGCACCACCGGCGTGGAGCGGGCACTGCTGCGACGC
CTGCCCGCGCTCGGCAAGGCGATCCGCAGCGCCTACTACACCGGCATCGAGAGCTTCGGCCTGGTCGGTTTCGTGGACAA
GCGCTTCCGTCACCCGTTCGAGACCTTGGCCAAACTGCAACTGCTGCGGCAGGTCCGCGATCCGCGGCTGCGGCGCATCC
TCACCCCCGACTATGTGATCGGCTGTAAGCGGGCGATCTTCTCCGACGCCTACTATCCCGCCCTGACCCAGCCGAACGTC
GAGGTCGTCACCGCGGGCATCGCCGAGATCCGGCCGCACTCCATCGTCACCGTGGACGGCGCCGAGTACCCGATCGACAC
GCTGATCTGGGGCACCGGCTTCGGGGTGCCGCCCGCGATCTTCCAGCGGGTGCACGGCGTCGACGGACGCTCCATCGCCG
ACATCTACCGGGAACGGCCCAGCAGCTACCTCGGCGCGGCCATCGGCGGATTCCCGAACTTCTTCTGCACCCTCGGCCCG
TTCGGCGCGGCGGGCAACCAGTCGGCCATCTTCATGATCGAGGCGCAGGCCCGCTACATCGTCGACGCGCTGAAAACCAT
GCGCGCCCAGCGTGTCACGCGGGTGGCGGTGCGCCCGGAGGTGCAGCGAGCCTTCCTCGACGACGTCAACGCCCGCAGTC
GCGACACCGCCTGGCTGACCGGCGGGTGCCGCAGCTACTACCAGACCGCCGACGGCGCCAACTCCGGTCTGTACCCGAAC
TGGAGCTTCGAATACGCTCGCCGCACACGGCATTTCGACGCCGACTCGTACGAGATGAGGACCCGATGA

Upstream 100 bases:

>100_bases
AGGTGGATCACCGCGACCGCGCGTTGTCGGCCGCCGAGCGAGCCGAATCGATGCTCACCTGCGTCTCGCGCGCCGCCGAC
GGCGACCTGGTGCTGGATCT

Downstream 100 bases:

>100_bases
AACTGCCAGGGCTGCGCGGACTGCTCGCCGCCGTCCCGTTCGCCGCGGTCTCCGGCCCGCCGATCTTCGACCTGGAGGGA
CGGGTCGCGCTGGTCACCGG

Product: putative monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKGHPPREGVAAVATDNTAAHVPVVIIGAGIAGIALGVELRAAGLTDFVVLERAEGLGGTWRANTYPGCACDVPSQLYSY
SFAPNPDWSRTYGTQPEILGYLERVATEHGVVAHMRFGTELRDARWDEDAEVWRVSTSRGDYTAGVLISAVGPFSEASIP
DLPGRASFAGTQFHSLHWDHEHDLRGERVAVIGTGASAVQFIPEIQPLVGQLTVFQRSAPWIVSRLDRSTTGVERALLRR
LPALGKAIRSAYYTGIESFGLVGFVDKRFRHPFETLAKLQLLRQVRDPRLRRILTPDYVIGCKRAIFSDAYYPALTQPNV
EVVTAGIAEIRPHSIVTVDGAEYPIDTLIWGTGFGVPPAIFQRVHGVDGRSIADIYRERPSSYLGAAIGGFPNFFCTLGP
FGAAGNQSAIFMIEAQARYIVDALKTMRAQRVTRVAVRPEVQRAFLDDVNARSRDTAWLTGGCRSYYQTADGANSGLYPN
WSFEYARRTRHFDADSYEMRTR

Sequences:

>Translated_502_residues
MKGHPPREGVAAVATDNTAAHVPVVIIGAGIAGIALGVELRAAGLTDFVVLERAEGLGGTWRANTYPGCACDVPSQLYSY
SFAPNPDWSRTYGTQPEILGYLERVATEHGVVAHMRFGTELRDARWDEDAEVWRVSTSRGDYTAGVLISAVGPFSEASIP
DLPGRASFAGTQFHSLHWDHEHDLRGERVAVIGTGASAVQFIPEIQPLVGQLTVFQRSAPWIVSRLDRSTTGVERALLRR
LPALGKAIRSAYYTGIESFGLVGFVDKRFRHPFETLAKLQLLRQVRDPRLRRILTPDYVIGCKRAIFSDAYYPALTQPNV
EVVTAGIAEIRPHSIVTVDGAEYPIDTLIWGTGFGVPPAIFQRVHGVDGRSIADIYRERPSSYLGAAIGGFPNFFCTLGP
FGAAGNQSAIFMIEAQARYIVDALKTMRAQRVTRVAVRPEVQRAFLDDVNARSRDTAWLTGGCRSYYQTADGANSGLYPN
WSFEYARRTRHFDADSYEMRTR
>Mature_502_residues
MKGHPPREGVAAVATDNTAAHVPVVIIGAGIAGIALGVELRAAGLTDFVVLERAEGLGGTWRANTYPGCACDVPSQLYSY
SFAPNPDWSRTYGTQPEILGYLERVATEHGVVAHMRFGTELRDARWDEDAEVWRVSTSRGDYTAGVLISAVGPFSEASIP
DLPGRASFAGTQFHSLHWDHEHDLRGERVAVIGTGASAVQFIPEIQPLVGQLTVFQRSAPWIVSRLDRSTTGVERALLRR
LPALGKAIRSAYYTGIESFGLVGFVDKRFRHPFETLAKLQLLRQVRDPRLRRILTPDYVIGCKRAIFSDAYYPALTQPNV
EVVTAGIAEIRPHSIVTVDGAEYPIDTLIWGTGFGVPPAIFQRVHGVDGRSIADIYRERPSSYLGAAIGGFPNFFCTLGP
FGAAGNQSAIFMIEAQARYIVDALKTMRAQRVTRVAVRPEVQRAFLDDVNARSRDTAWLTGGCRSYYQTADGANSGLYPN
WSFEYARRTRHFDADSYEMRTR

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=461, Percent_Identity=22.9934924078091, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4503757, Length=221, Percent_Identity=24.4343891402715, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI50541965, Length=351, Percent_Identity=24.2165242165242, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI50541961, Length=351, Percent_Identity=24.2165242165242, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI221316672, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI221316674, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI221316678, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145785, Length=349, Percent_Identity=22.3495702005731, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55255; Mature: 55255

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGHPPREGVAAVATDNTAAHVPVVIIGAGIAGIALGVELRAAGLTDFVVLERAEGLGGT
CCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHEEEECCCHHEEEEECCCCCCCC
WRANTYPGCACDVPSQLYSYSFAPNPDWSRTYGTQPEILGYLERVATEHGVVAHMRFGTE
EECCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCH
LRDARWDEDAEVWRVSTSRGDYTAGVLISAVGPFSEASIPDLPGRASFAGTQFHSLHWDH
HHHCCCCCCCCEEEEECCCCCEEHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCC
EHDLRGERVAVIGTGASAVQFIPEIQPLVGQLTVFQRSAPWIVSRLDRSTTGVERALLRR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHH
LPALGKAIRSAYYTGIESFGLVGFVDKRFRHPFETLAKLQLLRQVRDPRLRRILTPDYVI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
GCKRAIFSDAYYPALTQPNVEVVTAGIAEIRPHSIVTVDGAEYPIDTLIWGTGFGVPPAI
HHHHHHHCCCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCCHHHEEECCCCCCCHHH
FQRVHGVDGRSIADIYRERPSSYLGAAIGGFPNFFCTLGPFGAAGNQSAIFMIEAQARYI
HHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECHHHHH
VDALKTMRAQRVTRVAVRPEVQRAFLDDVNARSRDTAWLTGGCRSYYQTADGANSGLYPN
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCC
WSFEYARRTRHFDADSYEMRTR
CCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKGHPPREGVAAVATDNTAAHVPVVIIGAGIAGIALGVELRAAGLTDFVVLERAEGLGGT
CCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHEEEECCCHHEEEEECCCCCCCC
WRANTYPGCACDVPSQLYSYSFAPNPDWSRTYGTQPEILGYLERVATEHGVVAHMRFGTE
EECCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCH
LRDARWDEDAEVWRVSTSRGDYTAGVLISAVGPFSEASIPDLPGRASFAGTQFHSLHWDH
HHHCCCCCCCCEEEEECCCCCEEHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCC
EHDLRGERVAVIGTGASAVQFIPEIQPLVGQLTVFQRSAPWIVSRLDRSTTGVERALLRR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHH
LPALGKAIRSAYYTGIESFGLVGFVDKRFRHPFETLAKLQLLRQVRDPRLRRILTPDYVI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
GCKRAIFSDAYYPALTQPNVEVVTAGIAEIRPHSIVTVDGAEYPIDTLIWGTGFGVPPAI
HHHHHHHCCCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCCHHHEEECCCCCCCHHH
FQRVHGVDGRSIADIYRERPSSYLGAAIGGFPNFFCTLGPFGAAGNQSAIFMIEAQARYI
HHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECHHHHH
VDALKTMRAQRVTRVAVRPEVQRAFLDDVNARSRDTAWLTGGCRSYYQTADGANSGLYPN
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCC
WSFEYARRTRHFDADSYEMRTR
CCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]