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The map label for this gene is nhaR [H]

Identifier: 53723035

GI number: 53723035

Start: 2728076

End: 2728954

Strand: Reverse

Name: nhaR [H]

Synonym: BPSS2017

Alternate gene names: 53723035

Gene position: 2728954-2728076 (Counterclockwise)

Preceding gene: 53723039

Following gene: 53723033

Centisome position: 86.01

GC content: 73.27

Gene sequence:

>879_bases
ATGCTGAATTTTCGCCATCTGTACTACTTCTGGGTGGTCGTGAAGGAAGGCGGCTTCGCGCGCGCGGCCGGCCGGCTCGA
CATGGCCGTGCAGACGATCAGCGCGCAGGTGCGCGAGCTGGAGCGATCGATCGGGCACCAGTTGCTGAAGCCGGCGGGCC
GCGGCGTGACGATGACGGACGCCGGGCAGGCCGCGTTCGCGCGCGCCGAGGAAATCTTCCGGATCGGGCAACTGATCGAG
GACGAGGTGCGCGAGGCCGCGCGCGGCGAGGGCGTGCGGCTCGCGGTCGGCCTGACGGACGGCATCTCGAAGCTCACCGC
GCACGCGGTGCTCGAGCCCGCGCTCGCGGCGCCGTCGCTGCGGCTGCTGTGCCACGACGGCGAGTACGAGGAGCTGCTCG
GCGAGCTCGCGCTGCATCGGCTCGATCTCGTGCTCGCGGGCGAGCCCGCGCCGCGCCGCGCGAACCTGCGGCTTGCGAGC
GAGCGGATCGTCGCGTCGCCCGTCGACTGGTACGGGCCGACGGCGATCGCAGCGGCCGCGCGCGGTCGCTTTCCGCAGTG
CCTGGCCGAGTTGCCGGTGCTGTTGCCGACCGGGCACGCGGCGCTGCGCGCGCGGCTCGACCGCTGGTTCGATGCGCACG
GGATCAGGCCGCGAATCGTCGGCGAGTTCGAGGACAGCGCGCTGATGGCGGTGTTCGCCGCGCGCGGCCTCGGCGTGTTT
GCGCTCAGCGAGCCGGGCGCGGGCGACGTCGCGCTGCTGCGCGGGCTGCGGCGGCTCGGGCGCGCGCAGGGCGTGACCGA
GGAGATCTATGCGATCCGCTCGCATCGCGGCCAACATCATCCGCTTGTCGCGCAGGTGCTGGCCGCGGCGTCGCGGTGA

Upstream 100 bases:

>100_bases
GGAGGATGATCGGCGTTTTCGGATTTCGGAAAAACCAGTTGAAAACTGAATTATTATTCGGTTTTTACGAAGCTTGAATG
ACGACGGAGCGACGGGCGCG

Downstream 100 bases:

>100_bases
GCGGCGCGCACCGTTCGCGCGCGCGAAGCCCTTCGTCTGCGGCAGACTGCGGCGCGCATGAAGGCCGAACGCGAAGATCG
TGCCGCTCGCGATGAACGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLNFRHLYYFWVVVKEGGFARAAGRLDMAVQTISAQVRELERSIGHQLLKPAGRGVTMTDAGQAAFARAEEIFRIGQLIE
DEVREAARGEGVRLAVGLTDGISKLTAHAVLEPALAAPSLRLLCHDGEYEELLGELALHRLDLVLAGEPAPRRANLRLAS
ERIVASPVDWYGPTAIAAAARGRFPQCLAELPVLLPTGHAALRARLDRWFDAHGIRPRIVGEFEDSALMAVFAARGLGVF
ALSEPGAGDVALLRGLRRLGRAQGVTEEIYAIRSHRGQHHPLVAQVLAAASR

Sequences:

>Translated_292_residues
MLNFRHLYYFWVVVKEGGFARAAGRLDMAVQTISAQVRELERSIGHQLLKPAGRGVTMTDAGQAAFARAEEIFRIGQLIE
DEVREAARGEGVRLAVGLTDGISKLTAHAVLEPALAAPSLRLLCHDGEYEELLGELALHRLDLVLAGEPAPRRANLRLAS
ERIVASPVDWYGPTAIAAAARGRFPQCLAELPVLLPTGHAALRARLDRWFDAHGIRPRIVGEFEDSALMAVFAARGLGVF
ALSEPGAGDVALLRGLRRLGRAQGVTEEIYAIRSHRGQHHPLVAQVLAAASR
>Mature_292_residues
MLNFRHLYYFWVVVKEGGFARAAGRLDMAVQTISAQVRELERSIGHQLLKPAGRGVTMTDAGQAAFARAEEIFRIGQLIE
DEVREAARGEGVRLAVGLTDGISKLTAHAVLEPALAAPSLRLLCHDGEYEELLGELALHRLDLVLAGEPAPRRANLRLAS
ERIVASPVDWYGPTAIAAAARGRFPQCLAELPVLLPTGHAALRARLDRWFDAHGIRPRIVGEFEDSALMAVFAARGLGVF
ALSEPGAGDVALLRGLRRLGRAQGVTEEIYAIRSHRGQHHPLVAQVLAAASR

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=286, Percent_Identity=31.8181818181818, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788297, Length=254, Percent_Identity=27.5590551181102, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=28.3842794759825, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31642; Mature: 31642

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAGRLDMAVQTISAQVRELERSIGHQLLKPAGRGVTMTD
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
AGQAAFARAEEIFRIGQLIEDEVREAARGEGVRLAVGLTDGISKLTAHAVLEPALAAPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCE
RLLCHDGEYEELLGELALHRLDLVLAGEPAPRRANLRLASERIVASPVDWYGPTAIAAAA
EEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEHHHHHHCCCCCCCCHHHHHHHH
RGRFPQCLAELPVLLPTGHAALRARLDRWFDAHGIRPRIVGEFEDSALMAVFAARGLGVF
CCCCHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHCCCCEE
ALSEPGAGDVALLRGLRRLGRAQGVTEEIYAIRSHRGQHHPLVAQVLAAASR
EECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAGRLDMAVQTISAQVRELERSIGHQLLKPAGRGVTMTD
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
AGQAAFARAEEIFRIGQLIEDEVREAARGEGVRLAVGLTDGISKLTAHAVLEPALAAPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCE
RLLCHDGEYEELLGELALHRLDLVLAGEPAPRRANLRLASERIVASPVDWYGPTAIAAAA
EEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEHHHHHHCCCCCCCCHHHHHHHH
RGRFPQCLAELPVLLPTGHAALRARLDRWFDAHGIRPRIVGEFEDSALMAVFAARGLGVF
CCCCHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHCCCCEE
ALSEPGAGDVALLRGLRRLGRAQGVTEEIYAIRSHRGQHHPLVAQVLAAASR
EECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]