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The map label for this gene is lipA1

Identifier: 53722762

GI number: 53722762

Start: 2390190

End: 2391284

Strand: Reverse

Name: lipA1

Synonym: BPSS1741

Alternate gene names: 53722762

Gene position: 2391284-2390190 (Counterclockwise)

Preceding gene: 53722763

Following gene: 53722761

Centisome position: 75.36

GC content: 66.94

Gene sequence:

>1095_bases
ATGGCCAGAACGATGCGATCCAGGGCAGTGGCGGCGGCAGTCGCGTTCGCGGTGAGCGCGGCGCCCGCCGCGGGCATCGG
GACTTTCCTCTCGCTTGCAGGCACGCAAGCCGCCGCCGCGGCGACGAGCGCCGTCGACAACTACGCGGCCACCCAATATC
CGATCATCCTCGTGCACGGTCTGACCGGCACCGACAAATACGCGAACGTTCTCGAATACTGGTACGGCATCCGGGAAGAC
TTGCAGGCGCACGGCGCGCAGGTCTATGTCGCGAACCTGTCCGGCTTCCAGAGCGACGACGGGCCGAACGGACGCGGCGA
ACAGCTGCTCGCATACGTGCAGCAGGTGCTCGCCGCGACGGGCGCATCGAAGGTGAATCTGATCGGCCACAGCCAGGGCG
GGCTGACCTCGCGCTACGTCGCGGCCGTCGCGCCGCAACTGGTCGCATCGGTGACGACGATCGGCACGCCGCATCGCGGT
TCGGAGTTCGCGGACTTCGTGCAAACCGTGCTCGCGTACGATCCGACCGGCTTGTCGTCGACGGTGATCGCCGCGTTCGT
CAATGTGTTCGGCATCCTGACGAGCAGCACCAACAACACGAACCAGGACGCGCTCGCCGCGCTGAAGACGCTGACGACTT
CGCAGGCCGCGACGTACAACCAGAACTATCCGAGCGCGGGCCTCGGCGCGCCGGGCTCGTGCCAGACAGGGGCGCAGACC
GAGACCGTAGGCGGCAACACGCATCTGCTGTATTCGTGGGGTGGCACGGCGATCCAGCCGACGCTGTCGATTCTCGGCGT
GACGGGCGCGACCGACACGAGCACGATTCCCGTCGTCGATCCGGCGAACGTGCTCGATGCGTCGACGCTCGCGATGCTCG
GCTCCGGCACCGTGATGATCAATCGCGGCTCCGGTGCGAACGACGGCCTCGTGTCGCGCTGCAGCTCGCTGTACGGCCAG
GTGCTCGGCACGAGCTACAAGTGGAACCACCTCGACGAGATCAACCAGTTGCTCGGCGTGCGCGGCGCGTACGCGGAGGA
TCCGGTCGCGGTGATCCGCACGCATGCGAACCGGTTGAAGACGCAGGGTGTGTGA

Upstream 100 bases:

>100_bases
GGGTCGGCGTGCATGCCGCGTGTGCGGGCGACGCGAAACGTAGGCGTGCGAACAGAAGCAATATTCCCATCCGATACGAT
TCAAACAACAGGAGACGTAC

Downstream 100 bases:

>100_bases
TCGATGAAGGGAGAAGGCAGCGTTGCGCGGCGCGTCGCGCTTTACTGTGTGGCCGGCGCTGTCGCGGCCGGCGCGGTGTG
GTATGTCGTCGGCGCGCCGG

Product: lipase precursor

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MARTMRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIRED
LQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRG
SEFADFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQT
ETVGGNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQ
VLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV

Sequences:

>Translated_364_residues
MARTMRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIRED
LQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRG
SEFADFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQT
ETVGGNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQ
VLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV
>Mature_363_residues
ARTMRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIREDL
QAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGS
EFADFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTE
TVGGNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQV
LGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=165, Percent_Identity=30.9090909090909, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 37404; Mature: 37273

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTMRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHG
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEC
LTGTDKYANVLEYWYGIREDLQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAAT
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQTVLAYDPTGLSS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHH
TVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ETVGGNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMI
EECCCCEEEEEECCCCCCCCHHHEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEE
NRGSGANDGLVSRCSSLYGQVLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLK
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TQGV
CCCC
>Mature Secondary Structure 
ARTMRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEC
LTGTDKYANVLEYWYGIREDLQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAAT
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQTVLAYDPTGLSS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHH
TVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ETVGGNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMI
EECCCCEEEEEECCCCCCCCHHHEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEE
NRGSGANDGLVSRCSSLYGQVLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLK
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TQGV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1987151; 9032073; 9032074 [H]