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The map label for this gene is soxB

Identifier: 53722395

GI number: 53722395

Start: 1873103

End: 1874347

Strand: Reverse

Name: soxB

Synonym: BPSS1369

Alternate gene names: 53722395

Gene position: 1874347-1873103 (Counterclockwise)

Preceding gene: 53722396

Following gene: 53722394

Centisome position: 59.07

GC content: 67.15

Gene sequence:

>1245_bases
ATGAGCCGCTACTCGATATTCAGCCTGTTTCGCAACGGCCTGTCGTATCACGAGAACTGGGAAAAGCAGTGGAAGAGCCC
GGAGCCGAAGCGCGAGTACGACGTCGTGATCGTCGGCGGCGGCGGGCATGGGCTCGCCACCGCGTACTACCTCGCGAAGG
AGCATGGCGTGACGAACGTCGCGATTCTCGAGAAGGGCTGGATCGGCGGCGGCAACACCGCGCGCAACACGACGATCGTC
CGCTCGAACTACCTGTGGGACGAATCCGCCGGGCTCTACGAGAAGGCGATGAAGCTGTGGGAAGGGCTCGCGCAGGACTT
GAACTACAACGTGATGTTCAGCCAGCGTGGCGTGATGAACCTCGCGCATACGCTGCAGGACGTGCGCGACACCGAGCGCC
GCGTGAACGCGAACCGGCTGAACGGCGTCGACGCCGAGTTCCTCACGCCCGCGCAGATCAAGGAGATCGAGCCGACGATC
AACCTGAACAGCCGCTACCCGGTGCTCGGCGCGTCGATCCAGCGGCGCGGCGGCGTGGCGCGGCACGACGCGGTGGCCTG
GGGCTTCGCGCGCGGCGCGGACCGCGCGGGCGTCGACATCATCCAGAACTGCCAGGTGACGGGCATCCGCCGCGAGGGCG
GGGCGGTGGTCGGCGTCGATACGGTCAAGGGCTTCATCAAGGCGAAGAAGGTCGCGGTGGTCGCGGCGGGCAACACGACG
ACGCTCGCCGACATGGCCGGCGTGCGGCTGCCGCTCGAAAGCCATCCGCTGCAGGCGCTCGTGTCCGAGCCGATCAAGCC
GGTCGTCAACACGGTCGTGATGTCGAACGCGGTGCATGCGTACATCAGCCAGTCCGACAAGGGCGACCTCGTGATCGGCG
CGGGTATCGACCAATACACGGGCTTCGGCCAGCGCGGCAGCTTCCAGATCATCGAAGGCACGCTGGAGGCGATCGTCGAG
ATGTTCCCGGTGTTCTCGCGCGTGCGGATGAACCGCCAGTGGGGCGGCATCGTCGACGTGTCGCCGGACGCGTGCCCGAT
CATCAGCAAGACCGACGTGAAGGGCCTGTATTTCAACTGCGGCTGGGGCACGGGCGGCTTCAAGGCGACGCCGGGCTCGG
GCTGGGTGTTCGCGCATACGATCGCGCGCGACGAGCCGCACGCGCTGAACGCGCCGTTCGCGCTCGACCGGTTCTACACC
GGCCACCTGATCGACGAGCACGGCGCGGCCGCCGTCGCGCATTGA

Upstream 100 bases:

>100_bases
ATGCGCGAGACGGGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGCCTCGCCGTGAACGTCATCGAATG
CTAACGAAGGGTCCATCAAC

Downstream 100 bases:

>100_bases
ACGAACCGCCGCGCATTGAGGCGCATGGGGCCGGGGGAGCGTTGAAGCGTGAACTCGGGTCGAGTGTGAAGCATGGGGCC
GGAGTAAGTGCTCAAGCGCC

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGVTNVAILEKGWIGGGNTARNTTIV
RSNYLWDESAGLYEKAMKLWEGLAQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKEIEPTI
NLNSRYPVLGASIQRRGGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFQIIEGTLEAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHALNAPFALDRFYT
GHLIDEHGAAAVAH

Sequences:

>Translated_414_residues
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGVTNVAILEKGWIGGGNTARNTTIV
RSNYLWDESAGLYEKAMKLWEGLAQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKEIEPTI
NLNSRYPVLGASIQRRGGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFQIIEGTLEAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHALNAPFALDRFYT
GHLIDEHGAAAVAH
>Mature_413_residues
SRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGVTNVAILEKGWIGGGNTARNTTIVR
SNYLWDESAGLYEKAMKLWEGLAQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKEIEPTIN
LNSRYPVLGASIQRRGGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTTT
LADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFQIIEGTLEAIVEM
FPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHALNAPFALDRFYTG
HLIDEHGAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=393, Percent_Identity=23.9185750636132, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI21361378, Length=393, Percent_Identity=23.9185750636132, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24797151, Length=397, Percent_Identity=23.6775818639798, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI194306651, Length=383, Percent_Identity=23.2375979112272, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787438, Length=328, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20130091, Length=383, Percent_Identity=24.0208877284595, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45098; Mature: 44966

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGVTNV
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEE
AILEKGWIGGGNTARNTTIVRSNYLWDESAGLYEKAMKLWEGLAQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKEIEPTINLNSRYPVLGASIQRRGGVA
HHHHHHHHHHHHHHCCCHHCCCCCCHHCCCHHHHHCCCCEECCCCCCCCCCCHHHCCCCC
RHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEEECCCEEEEHHHHHHHHEEEEEEEEECCCCC
TLADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYT
CHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFQIIEGTLEAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNC
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHALNAPFALDRFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHEECCEECCCCCEECCC
>Mature Secondary Structure 
SRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGVTNV
CCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEE
AILEKGWIGGGNTARNTTIVRSNYLWDESAGLYEKAMKLWEGLAQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKEIEPTINLNSRYPVLGASIQRRGGVA
HHHHHHHHHHHHHHCCCHHCCCCCCHHCCCHHHHHCCCCEECCCCCCCCCCCHHHCCCCC
RHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEEECCCEEEEHHHHHHHHEEEEEEEEECCCCC
TLADMAGVRLPLESHPLQALVSEPIKPVVNTVVMSNAVHAYISQSDKGDLVIGAGIDQYT
CHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFQIIEGTLEAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNC
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHALNAPFALDRFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHEECCEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]