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The map label for this gene is sdaB

Identifier: 53722396

GI number: 53722396

Start: 1874364

End: 1875749

Strand: Reverse

Name: sdaB

Synonym: BPSS1370

Alternate gene names: 53722396

Gene position: 1875749-1874364 (Counterclockwise)

Preceding gene: 53722398

Following gene: 53722395

Centisome position: 59.12

GC content: 68.4

Gene sequence:

>1386_bases
ATGAACGTCAGCGTTTTCGATCTGTTCAAGATCGGCATCGGTCCGTCGAGCTCGCATACCGTCGGGCCGATGATCGCCGC
GTGCCGGTTCGCGTCGCACGTCGAGGACGCGAACCTGCTCGGTTTCGTGCGCCGCGTGCGGGCCGAGCTGTACGGCTCGC
TCGGCGCGACGGGCAAGGGCCACGGCACCGACAAGGCGGTGCTGCTCGGCCTCGAAGGGCACTTGCCCGATTCGGTCGAC
CCCGATCTGATCGAGCCCCGCTTGAAGGCGATCCGCGCGGAGAAGTCGCTCGCGTTGCTCGGCAAGCGCGGCATCCGCTT
CGACGAGAAGGACGACATCGGCTTCTACCGCAAGCTGATGAGCGGCACGAGCGTCGTCCATCCGAACGGCATGCGCTTCC
AGGCGTTCGACGAGCACGGCCAGTTGCTCGTCGAGAAGGAGTATTACTCGGTCGGCGGCGGCTTCGTCGTCAATCGCGAC
GGCGATCGCGTGAACGGCGTGCGTGCGGCGGCCGACGTGCCGTATCCGTTTCGCACCGGCGACGATCTGATGCGCGCGTG
CCGCGCGAGCGGCCTGTCGATCGCCGAGCTCACGTTTCGCAACGAGTGCGCGCTGCGCCCGGCCGACGAGGTGCGCGCGG
GCCTCGTCGCGATCTGGAGGACGATGGCCGCGTGCGTCGAGCGCGGCTGCAAGGCCGACGGCGAGCTGCCCGGCCCGATG
CGCGTGAAGCGCCGCGCGGCCGAGCTCTACACGCGGCTGCGCGATCGGTCGGAGGAATCGCTGCGCGATCCGCTGTCGAT
GCTCGACTGGGTAAACCTCTATGCGATGGCGGTCAACGAGGAGAACGCGGCGGGCGGGCGCGTCGTCACCGCGCCGACGA
ACGGCGCGGCGGGCGTGATTCCGGCCGTGCTCCATTACTACGTGAAGTTCGTGCCGGGCTCGACCGAGCAGGGGATCGTC
GATTTCCTGCTGACCGCCGCCGCGATCGGGATCATCTACAAGGAAACCGCGTCGATCTCCGGCGCGGAGGTCGGCTGCCA
GGGCGAGGTGGGCGTCGCGTGCTCGATGGCCGCGGCCGCGCTCGCCGCGGTGATGGGCGGCACGCCCGGCCAGGTCGAGA
ACGCGGCCGAGATCGGCATGGAGCACAACCTCGGGATGACGTGCGATCCCGTGGGCGGCCTCGTGCAGATCCCGTGCATC
GAGCGCAACGCGATGGGCGCGATCAAGGCGCTCAACGCGTCGCGCCTCGCGCTCAAGGGCGACGGCCAGCACTACGTGTC
GCTCGATTCCGTCATCAAGACGATGCGCGAGACGGGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGCC
TCGCCGTGAACGTCATCGAATGCTAA

Upstream 100 bases:

>100_bases
GCGTCCCACGCCGATGCCGTTTTTGTTCTATCGGCGGATTTTACGCTTTGATGTACTGACGCCCAACGTCAACCAAGCAT
CGTCACGCAAGGGCAGCCAG

Downstream 100 bases:

>100_bases
CGAAGGGTCCATCAACATGAGCCGCTACTCGATATTCAGCCTGTTTCGCAACGGCCTGTCGTATCACGAGAACTGGGAAA
AGCAGTGGAAGAGCCCGGAG

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVD
PDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRD
GDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAELTFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPM
RVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSTEQGIV
DFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRLALKGDGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC

Sequences:

>Translated_461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVD
PDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRD
GDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAELTFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPM
RVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSTEQGIV
DFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRLALKGDGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
>Mature_461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVD
PDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRD
GDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAELTFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPM
RVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSTEQGIV
DFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRLALKGDGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=462, Percent_Identity=50.8658008658009, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1788116, Length=460, Percent_Identity=50.2173913043478, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=51.3100436681223, Blast_Score=443, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49178; Mature: 49178

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKG
CCCEEEEHEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
HGTDKAVLLGLEGHLPDSVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLM
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTG
CCCCEECCCCCEEEEECCCCCEEEEEHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCC
DDLMRACRASGLSIAELTFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPM
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHH
PAVLHYYVKFVPGSTEQGIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRLALKG
HHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEEC
DGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
CCCEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKG
CCCEEEEHEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
HGTDKAVLLGLEGHLPDSVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLM
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTG
CCCCEECCCCCEEEEECCCCCEEEEEHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCC
DDLMRACRASGLSIAELTFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPM
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHH
PAVLHYYVKFVPGSTEQGIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRLALKG
HHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEEC
DGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
CCCEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]