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The map label for this gene is dppA [H]

Identifier: 53722326

GI number: 53722326

Start: 1782617

End: 1783444

Strand: Reverse

Name: dppA [H]

Synonym: BPSS1302

Alternate gene names: 53722326

Gene position: 1783444-1782617 (Counterclockwise)

Preceding gene: 53722327

Following gene: 53722323

Centisome position: 56.21

GC content: 72.1

Gene sequence:

>828_bases
ATGAAAGTCCTGATTTCGACCGATATCGAAGGCGTGGCGGGCGTCGTGAGCGTCGAGCAGACGCGCGCCGGCAATCCCGA
ATACGAGCGCGCGCGCCGCTGGATGACCGCGGAGGCGAACGCGGCCGTCGAGGGCGCATTCGCGGGCGGCGCGACGCGCG
TGTGGGTCAACGATTCGCACGGCGGCTTTCGCAACCTGCTGCCCGACGGGATCGACGCGCGCGCGCGCGTCGTACTCGGC
AAGCCGCGCCCGCTCGGAATGATGGCGGGCCTCGAGGCGGGGCCGGACCTCGTGTTCATGATCGGCTATCACGCGAAGGC
GCAGACGCGCGGGCTGCTCGCGCACACGATCAACAGCAGCGCGTTCGCGCGCGTCGTGCTCGACGGGCGCGACGTCGGCG
AGGCGGGGCTCTACGGCGCGCTCGCGCACGAATACGGCGCGCATGTCGCGCTTTTGTCCGGCGACGACGTGTTCGTCGAC
GAGACGCGGCCGCTCTTTCCGGCGGCGCAGTTCGTGACCGTGAAGGAGGCGGCGGGATTCGCGAGCGGCGCGTCGATGAC
GCCCGCGGCCGCATGCGGGGCGATCGGCGTGGCCGCGCGGCAGGCGGTCGAGCAGGCGCGCGAGGGGGCGCGCGCGGCGC
GCCCGCATGCGCCGCGCGCGGCGCGTTGCGAGCTGCAGGCGCAGAGCGTCGCGGCCGCCGACCTGTTCTGTCAGTGGCCG
TCGCTCGAGCGCGTCGACGCGCTCACGCTGCGCTTTTTCGCGCCATCGATCGAGCACGTCGTGCGGACGCTGAACTGCCT
GTCGGCGATGTCGTTCATGCTGAGGTGA

Upstream 100 bases:

>100_bases
CGACGCGCGTCACCGGCCGCGACGGTCACACACGGCGCGCGTTGCGCGACGCCGCGCCGGAACTCGAACGATGGTTGCGC
GCGGCGCGCGCGGGAGCATG

Downstream 100 bases:

>100_bases
ACGCGCCGGGGCGCGCCCTCGCGCGGCGGCGCGCGGGCGCGTAGGGCTATGACGATGCGCCGCGGCTCGCTTGCAGGCGG
CCGCGTGGCGCGCCGGACGG

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKVLISTDIEGVAGVVSVEQTRAGNPEYERARRWMTAEANAAVEGAFAGGATRVWVNDSHGGFRNLLPDGIDARARVVLG
KPRPLGMMAGLEAGPDLVFMIGYHAKAQTRGLLAHTINSSAFARVVLDGRDVGEAGLYGALAHEYGAHVALLSGDDVFVD
ETRPLFPAAQFVTVKEAAGFASGASMTPAAACGAIGVAARQAVEQAREGARAARPHAPRAARCELQAQSVAAADLFCQWP
SLERVDALTLRFFAPSIEHVVRTLNCLSAMSFMLR

Sequences:

>Translated_275_residues
MKVLISTDIEGVAGVVSVEQTRAGNPEYERARRWMTAEANAAVEGAFAGGATRVWVNDSHGGFRNLLPDGIDARARVVLG
KPRPLGMMAGLEAGPDLVFMIGYHAKAQTRGLLAHTINSSAFARVVLDGRDVGEAGLYGALAHEYGAHVALLSGDDVFVD
ETRPLFPAAQFVTVKEAAGFASGASMTPAAACGAIGVAARQAVEQAREGARAARPHAPRAARCELQAQSVAAADLFCQWP
SLERVDALTLRFFAPSIEHVVRTLNCLSAMSFMLR
>Mature_275_residues
MKVLISTDIEGVAGVVSVEQTRAGNPEYERARRWMTAEANAAVEGAFAGGATRVWVNDSHGGFRNLLPDGIDARARVVLG
KPRPLGMMAGLEAGPDLVFMIGYHAKAQTRGLLAHTINSSAFARVVLDGRDVGEAGLYGALAHEYGAHVALLSGDDVFVD
ETRPLFPAAQFVTVKEAAGFASGASMTPAAACGAIGVAARQAVEQAREGARAARPHAPRAARCELQAQSVAAADLFCQWP
SLERVDALTLRFFAPSIEHVVRTLNCLSAMSFMLR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 29070; Mature: 29070

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLISTDIEGVAGVVSVEQTRAGNPEYERARRWMTAEANAAVEGAFAGGATRVWVNDSH
CEEEEECCCCCHHHEEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCC
GGFRNLLPDGIDARARVVLGKPRPLGMMAGLEAGPDLVFMIGYHAKAQTRGLLAHTINSS
CCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCEEEECCCC
AFARVVLDGRDVGEAGLYGALAHEYGAHVALLSGDDVFVDETRPLFPAAQFVTVKEAAGF
CEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCCHHEEEEHHHCCC
ASGASMTPAAACGAIGVAARQAVEQAREGARAARPHAPRAARCELQAQSVAAADLFCQWP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHEECCC
SLERVDALTLRFFAPSIEHVVRTLNCLSAMSFMLR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLISTDIEGVAGVVSVEQTRAGNPEYERARRWMTAEANAAVEGAFAGGATRVWVNDSH
CEEEEECCCCCHHHEEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCC
GGFRNLLPDGIDARARVVLGKPRPLGMMAGLEAGPDLVFMIGYHAKAQTRGLLAHTINSS
CCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCEEEECCCC
AFARVVLDGRDVGEAGLYGALAHEYGAHVALLSGDDVFVDETRPLFPAAQFVTVKEAAGF
CEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCCHHEEEEHHHCCC
ASGASMTPAAACGAIGVAARQAVEQAREGARAARPHAPRAARCELQAQSVAAADLFCQWP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHEECCC
SLERVDALTLRFFAPSIEHVVRTLNCLSAMSFMLR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]