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The map label for this gene is pcaQ [H]

Identifier: 53722323

GI number: 53722323

Start: 1779761

End: 1780765

Strand: Reverse

Name: pcaQ [H]

Synonym: BPSS1299

Alternate gene names: 53722323

Gene position: 1780765-1779761 (Counterclockwise)

Preceding gene: 53722326

Following gene: 53722321

Centisome position: 56.12

GC content: 73.93

Gene sequence:

>1005_bases
ATGCATAACCGGATCGCCGACGGCCGGGTCAAGTTCCGGCACCTGCAGTGCTTTCTCGCCGTTGCGCAGTTCGGCAGCGT
GCAGAAGGCCGCGCACAGCCTGTCGATCACGCAGCCCGCCGTGTCGAAGACGATCGCCGAGCTCGAATCGATCCTCGGCG
TGCGGCTGTTCGAGCGCGGCCGGCAGGGCGCGCGGCCCACGCGCGAGGGCCAGCTTTTCATGCCGCACGCGAGCGCGTGC
GTGCTCGCGCTGCGGCAGGGCGTGGGGCTGCTCGCGCGCGAGGGCGGCGGCGCGGCGGCCACTCTCGAGATCGGCATGCT
GCCGACCGTCGCCGCGTCGCTCGCGCCCGCCGTGCTGAAAACGCTCGCGGCCGAATGGCCGCGCGCGGTCGTGCGGATCA
CGACCGTCGCGAACGCCGAGCTGCTCGAGCGGCTGAAGGCGGGGGCAATCGAATGCGCGATCGGGCGGCTGTCGGAGCCC
GAGCGGATGGTGGGGCTGTCGTTCGAGCATCTGTACAACGAGCCGCTCGTCGCGGTCGTGCGCGCGGGCCATCCGCTTGC
GGCGAGCGCTTCGCCCGCCGCGCAGCTCGCGCGCTATCCGGTCGTGCTGCCGCCTTACGGCACGATGATCCGGCAAGCGG
CCGAGCAATTGTTGAGCGCGTGCGGCGCGCCGCCGCTCGAATCGTTCGTCGAGGTGCTGTCGGTGTCGGTCGCGCGCGCG
CTCGCGCTCGAGAACGACGCGGTGTGGTTCGTGCCGCGCTACGCGGCCGAATTCGATCTCGCGGCCGGCACGCTCACGCG
GCTCGCGCTGCCCGTCGACGGCGCGGACGAGCCGGTCGGGCTGATCCTGCGCACCGACGCGCAGCCGTCACCCGTCGCGC
GCGCGCTGATCGACGCGGTGCGCGCGATTGCGCGGCGGCGGCTTGCCGGAGCGGGCACGACGAGCGGGCGCGCGCGCGGC
GCGCGAGGCGCGACGGGCAAGGGGCGCGGTCGGCGGGACGCGTGA

Upstream 100 bases:

>100_bases
GTCTCCAGATTGATGATTGTCAAGGGGGGTGACAGGACTTTAGCTAATGCGGAAAGTTATGCAAAATGATGTTTTATCGC
GAATCGTATAACTAACTGTT

Downstream 100 bases:

>100_bases
GGCCGGCGGCCGGCGTTCGACGCCGTGACGGCGCGGCGACGATCGGTTTTGCGGATCGGACCGGCAAGCGACCGGGCGTG
TAGGGTTCCGGGCGGAGCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHNRIADGRVKFRHLQCFLAVAQFGSVQKAAHSLSITQPAVSKTIAELESILGVRLFERGRQGARPTREGQLFMPHASAC
VLALRQGVGLLAREGGGAAATLEIGMLPTVAASLAPAVLKTLAAEWPRAVVRITTVANAELLERLKAGAIECAIGRLSEP
ERMVGLSFEHLYNEPLVAVVRAGHPLAASASPAAQLARYPVVLPPYGTMIRQAAEQLLSACGAPPLESFVEVLSVSVARA
LALENDAVWFVPRYAAEFDLAAGTLTRLALPVDGADEPVGLILRTDAQPSPVARALIDAVRAIARRRLAGAGTTSGRARG
ARGATGKGRGRRDA

Sequences:

>Translated_334_residues
MHNRIADGRVKFRHLQCFLAVAQFGSVQKAAHSLSITQPAVSKTIAELESILGVRLFERGRQGARPTREGQLFMPHASAC
VLALRQGVGLLAREGGGAAATLEIGMLPTVAASLAPAVLKTLAAEWPRAVVRITTVANAELLERLKAGAIECAIGRLSEP
ERMVGLSFEHLYNEPLVAVVRAGHPLAASASPAAQLARYPVVLPPYGTMIRQAAEQLLSACGAPPLESFVEVLSVSVARA
LALENDAVWFVPRYAAEFDLAAGTLTRLALPVDGADEPVGLILRTDAQPSPVARALIDAVRAIARRRLAGAGTTSGRARG
ARGATGKGRGRRDA
>Mature_334_residues
MHNRIADGRVKFRHLQCFLAVAQFGSVQKAAHSLSITQPAVSKTIAELESILGVRLFERGRQGARPTREGQLFMPHASAC
VLALRQGVGLLAREGGGAAATLEIGMLPTVAASLAPAVLKTLAAEWPRAVVRITTVANAELLERLKAGAIECAIGRLSEP
ERMVGLSFEHLYNEPLVAVVRAGHPLAASASPAAQLARYPVVLPPYGTMIRQAAEQLLSACGAPPLESFVEVLSVSVARA
LALENDAVWFVPRYAAEFDLAAGTLTRLALPVDGADEPVGLILRTDAQPSPVARALIDAVRAIARRRLAGAGTTSGRARG
ARGATGKGRGRRDA

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=299, Percent_Identity=39.4648829431438, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=28.2312925170068, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788887, Length=188, Percent_Identity=30.8510638297872, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790399, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788297, Length=171, Percent_Identity=30.4093567251462, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789506, Length=242, Percent_Identity=24.7933884297521, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=227, Percent_Identity=27.3127753303965, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789204, Length=182, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=229, Percent_Identity=24.8908296943231, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35141; Mature: 35141

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNRIADGRVKFRHLQCFLAVAQFGSVQKAAHSLSITQPAVSKTIAELESILGVRLFERG
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
RQGARPTREGQLFMPHASACVLALRQGVGLLAREGGGAAATLEIGMLPTVAASLAPAVLK
CCCCCCCCCCEEECCHHHHHHHHHHHCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHH
TLAAEWPRAVVRITTVANAELLERLKAGAIECAIGRLSEPERMVGLSFEHLYNEPLVAVV
HHHHHCCHHHEEEEHHCCHHHHHHHHHCHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHHE
RAGHPLAASASPAAQLARYPVVLPPYGTMIRQAAEQLLSACGAPPLESFVEVLSVSVARA
ECCCCCCCCCCHHHHHHHCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LALENDAVWFVPRYAAEFDLAAGTLTRLALPVDGADEPVGLILRTDAQPSPVARALIDAV
HHHCCCCEEEEECHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHH
RAIARRRLAGAGTTSGRARGARGATGKGRGRRDA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHNRIADGRVKFRHLQCFLAVAQFGSVQKAAHSLSITQPAVSKTIAELESILGVRLFERG
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
RQGARPTREGQLFMPHASACVLALRQGVGLLAREGGGAAATLEIGMLPTVAASLAPAVLK
CCCCCCCCCCEEECCHHHHHHHHHHHCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHH
TLAAEWPRAVVRITTVANAELLERLKAGAIECAIGRLSEPERMVGLSFEHLYNEPLVAVV
HHHHHCCHHHEEEEHHCCHHHHHHHHHCHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHHE
RAGHPLAASASPAAQLARYPVVLPPYGTMIRQAAEQLLSACGAPPLESFVEVLSVSVARA
ECCCCCCCCCCHHHHHHHCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LALENDAVWFVPRYAAEFDLAAGTLTRLALPVDGADEPVGLILRTDAQPSPVARALIDAV
HHHCCCCEEEEECHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHH
RAIARRRLAGAGTTSGRARGARGATGKGRGRRDA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]