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The map label for this gene is mocR [H]

Identifier: 53721754

GI number: 53721754

Start: 975934

End: 977442

Strand: Reverse

Name: mocR [H]

Synonym: BPSS0726

Alternate gene names: 53721754

Gene position: 977442-975934 (Counterclockwise)

Preceding gene: 53721756

Following gene: 53721753

Centisome position: 30.8

GC content: 74.09

Gene sequence:

>1509_bases
ATGGACTACGGTGTGTTGCTGTCGAACTTCGAACGGGACACCGCGCGCGACGCGCTCGCGCGCGCGTCGCAGCAGCACCG
GCTCTACGCGTGCCTGCGCGCGGCGATCCTGAACGGCACGCTCGAAGCCGGCACGTACCTGATGTCGTCGCGCGCGCTCG
CCGAGACGCTGCGGATCGCGCGCAACACGGTGCTCTACGCCTACGAACGGCTCGCCGCCGAGGGCTTCGTCGTCGCGCGG
CGGCAAGGCACGATGGTCGCGCGTGTGGGGCTGCCCGCGGCGAGCGCGACCGCCTCGCCCGCGCACGCGCGGCCCGCGCT
CGCGCGGCGCGTCACCGGGCTGCCGGACATCGACGCCGACGACGAGCGCGAGCCGCTGCCGTTCCTGCCGGGCATGCCCG
CGCTCGACCAGTTTCCGCTCGCGCCGTGGCGGCGCGCGGTCGAGCGCGCATGGCGGCGAATCGGTCCGGCGCAGCTCGGT
CACGCGCCGCTCGGCGGCAATCTGCGGCTGCGGCAGGCGATCGCCGAATATCTGCGCGTGTCGCGCGGCATCGGCTGCGA
TGCGCGGCAGGTGTTCATCACCGACGGCACGCAGCACGGCCTCGATCTGTGCGCGCGCACGCTCGCCGACGCGGGCGATA
CCGTCTGGATCGAACATCCCGGCTACGCCGGCGCGCGCGCCGCGTTCGAGGCGGCCGACCTGCGGCTCGTGCCGATCCCC
GTCGATGCGGACGGCCTCGCGCCGAGCGCCGAGCACTGGCGTGCGCATCCGCCGCGGCTTGTCTACATCACGCCGTCGCA
CCAGTATCCGCTCGGCGCGGTGATGAGCGTGGAGCGGCGCGTCGCGCTCGTCGCGAACGCGCGCGCGGCGGGCGCGTGGA
TCGTGGAGGACGATTACGACAGCGAGTTCCGCCACTTCGGCGCGCCGCTCGCCGCGCTGCAAAGTCTCGGCGACGACGCG
CCCGTCGTCTATCTCGGCACGTTCAGCAAGACGATGTTTCCGACGCTGCGCATCGGCTTCGTCGTCGCGTCGGCGGCGCT
CGCGCCGCAACTGCGCCACACGATCGGCGCGCTCGCGCCGCGCGGGCGCCTTGCCGAGCAGCTCGCGCTCGCCGACTTCA
TCGAAGCGGGCCATTTCACCCGGCATCTGCGCCGGATGCGCCGGCTCTACGAAGAGCGGCGCGACGCACTGCAGGACGCG
CTCGCGCGCCATCTCGGCGGCGCGCTGACGGTGTCGGGCGGCGCGGGCGGCATGCATCTGTCCGCGCGGCTCGATGCGCC
TGTCGCCGACGTCGACGTCGCGCGCGCGGCGCTCGCCCGCGCGATCACCGTGCGGCCGCTGTCGCGCTTCTGCCTGCCGG
GCACCGATCGCGCCGCATACAACGGCCTCGTGCTCGGCTACGGCGCGGTGCCGACCGAGCAGATCGACGCTTGCGTGCGG
CGGCTCGGCGCCGCGATCGACGATGCGCTGCGCGAGGTGACGCGGGCGCCGCGCGACGCCGCGAGATGA

Upstream 100 bases:

>100_bases
CGGGGCTCCTGCATCGGCATGTTCGTTTCGAAGAGCTCGACGATAGAAAATCTGTGGCACCATGGATAGATCCATGCGAT
TACTGAATTTTGGAGCCACG

Downstream 100 bases:

>100_bases
ACCCCATGGCGGCGCGCGAGCGCGGCGTCTTCGCTTCGTCGGCGGCCACTATCGCCTCTGCATCCTCTGCAGCCGCCGCT
GCCTCTATCGCCTCTATCGC

Product: GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERLAAEGFVVAR
RQGTMVARVGLPAASATASPAHARPALARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLG
HAPLGGNLRLRQAIAEYLRVSRGIGCDARQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEAADLRLVPIP
VDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLAALQSLGDDA
PVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDA
LARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVPTEQIDACVR
RLGAAIDDALREVTRAPRDAAR

Sequences:

>Translated_502_residues
MDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERLAAEGFVVAR
RQGTMVARVGLPAASATASPAHARPALARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLG
HAPLGGNLRLRQAIAEYLRVSRGIGCDARQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEAADLRLVPIP
VDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLAALQSLGDDA
PVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDA
LARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVPTEQIDACVR
RLGAAIDDALREVTRAPRDAAR
>Mature_502_residues
MDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERLAAEGFVVAR
RQGTMVARVGLPAASATASPAHARPALARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLG
HAPLGGNLRLRQAIAEYLRVSRGIGCDARQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEAADLRLVPIP
VDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLAALQSLGDDA
PVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDA
LARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVPTEQIDACVR
RLGAAIDDALREVTRAPRDAAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=319, Percent_Identity=24.1379310344828, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI33469970, Length=319, Percent_Identity=24.1379310344828, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1787710, Length=475, Percent_Identity=26.7368421052632, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790797, Length=464, Percent_Identity=26.2931034482759, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54238; Mature: 54238

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RNTVLYAYERLAAEGFVVARRQGTMVARVGLPAASATASPAHARPALARRVTGLPDIDAD
HHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
DEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLGHAPLGGNLRLRQAIAEYLRV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHH
SRGIGCDARQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEAADLRLVPIP
HCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCEEEEEEC
VDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYD
CCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEECCCC
SEFRHFGAPLAALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAP
HHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDALARHLGGALTVSGGAGGMHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
SARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVPTEQIDACVR
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCHHHHHHHHH
RLGAAIDDALREVTRAPRDAAR
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RNTVLYAYERLAAEGFVVARRQGTMVARVGLPAASATASPAHARPALARRVTGLPDIDAD
HHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
DEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLGHAPLGGNLRLRQAIAEYLRV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHH
SRGIGCDARQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEAADLRLVPIP
HCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCEEEEEEC
VDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYD
CCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEECCCC
SEFRHFGAPLAALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAP
HHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDALARHLGGALTVSGGAGGMHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
SARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVPTEQIDACVR
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCHHHHHHHHH
RLGAAIDDALREVTRAPRDAAR
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]