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The map label for this gene is crp [C]

Identifier: 53721756

GI number: 53721756

Start: 979524

End: 980234

Strand: Reverse

Name: crp [C]

Synonym: BPSS0730

Alternate gene names: 53721756

Gene position: 980234-979524 (Counterclockwise)

Preceding gene: 53721759

Following gene: 53721754

Centisome position: 30.89

GC content: 69.2

Gene sequence:

>711_bases
GTGCGAGCGCCGGCCGCGGCGGCCGGCGCGGGCGAGCTGCGCGCGCTGTTCTCCCGCTGCGGCTGGTTCAACACGCTCGC
GCCCGAGCATCAGGCGCTCGTCGTCGCGCAGTCGCACGCCGAGTACCGCGACGCGGGCGACTGGGTCGCGCGCCGGCAGG
CGCCTTCCGAATACTGGATCGGCGTGCACCGCGGGCTCGTGAAGCTCGCGATCTACAACGCGTCCGGGCGCGGCTGCACG
TTCTCCGGCGTGCCGTCGGGCGGCTGGTTCGGCGAAGGCAGCGTGATCAAGCGCGAGCTGCGCAAGTACGACGTGATCGC
GATCCAGCGCTCGCTCGTGCTGTTCGTGCCGAGCGCGACGTTCCACGCGCTCCTCGACAGCAGCCTGCCGTTCACGGGCT
TCGTGATCCGCCAGTTGAACAACCGGATGGGCGAATTCATCGCGTCGATCCAGAACAGCCGGCTACTCGACGTGAACGCG
CGCGTCGCGCAGTCGCTCGCCCAGCTGTTCAACCCGGACCTGTATCCGGACACCGGCGCGACGCTCGCGATCTCGCAGGA
GGAGCTCGGGATGCTGGTCGGCGTGTCGCGGCAGCGAATCAATCAGGCGCTTCAGCATCTCGAGCGGCTCGGCGCGGTGC
GGCTCGCGTACAACCAGATCGACGTGCTCGATCTGCCGAAGCTCGCGGCGTTCGGGATGGAGCAGATCTGA

Upstream 100 bases:

>100_bases
GGATGAAGCGGCCCGCGCCGACGAGGCTGCCGCAGAGCCTGCCTCGGCGCCGGCCGAAGCGCCCGTCGAAGCGCCCGTCG
AAACATCAGCCGCCGCGCCC

Downstream 100 bases:

>100_bases
CGGCCCGGTTGGCGGCCGCGGCCGCCATCGCGTTTCGCCGTCCATGATGCCGACCGGTCGCGGCCACGCGCGGCCTGCGC
TGTCGCCGCCGCCGTCCGCT

Product: regulatory protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcription Regulator Protein; Cyclic-Nucleotide-Gated Cation Channel; CNMP Regulatory Protein; HTH Crp Family Transcriptional Regulator; Regulatory Protein; Transcriptional Regulator Crp; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCT
FSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNA
RVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Sequences:

>Translated_236_residues
MRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCT
FSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNA
RVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
>Mature_236_residues
MRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCT
FSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNA
RVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25894; Mature: 25894

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHH
GVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSAT
HHHHCEEEEEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHH
FHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCCCC
TLAISQEELGMLVGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHH
GVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSAT
HHHHCEEEEEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHH
FHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCCCC
TLAISQEELGMLVGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA