| Definition | Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_006350 |
| Length | 4,074,542 |
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The map label for this gene is livF [H]
Identifier: 53721016
GI number: 53721016
Start: 4047620
End: 4048375
Strand: Reverse
Name: livF [H]
Synonym: BPSL3409
Alternate gene names: 53721016
Gene position: 4048375-4047620 (Counterclockwise)
Preceding gene: 53721017
Following gene: 53721015
Centisome position: 99.36
GC content: 62.04
Gene sequence:
>756_bases ATGGATCGAGAGGCGAAGCCGGTGTTGGCGGTACAGAATCTGTCGGTGCGCTACGGCAAGGTCGAGGCGTTGCATCGTGC GGCCCTGACGGTCGGAGCAGGGCAGATCGTCACAGTGATTGGGCCGAACGGGGCGGGAAAGTCGACGCTGCTCAATGCGG TGATGGGCGCGTTGCCGACGAATGGCCATGCTGCCGGTACGGTTCTTTACCGCGGCGACGATGTGGATGCATTGCCGGTC GAGCAGCGTGTCGCGCTCGGTATGTGCCTCGTGCCGGAAAAGCGTGAGCTATTCGGCACGATGTCGGTAGAGGACAATTT GGTGTTAGGCGCATACCGGCGAAAGATGGCCGGCGACGCGAGCTTCCTGGATCAGCTCGAGCCGGTTTTTTCGCTGTTTC CGAGGTTGAAGGAGCGACGCAAGCAAGCGGCCGGCACGCTTTCGGGTGGCGAGCGGCAGATGCTGGCTGTCGGGCGCGCG CTGATGGGCAAACCCGATTTGCTGATGCTCGACGAGCCGAGCCTTGGGCTTGCACCGCTGATCGTGAAGGAGATTTTCCA TATCATCAGCGCGCTGCGCGGGACCGGCGTTGCGACGCTGTTGATCGAGCAGAACGCGCGGGCGGCATTGCAGATATCGG ATTACGGGTATGTCCTCGAGACCAGTGAGATTGCTCTGGAGGGCCCGGCGGGCGAACTCGCGCAGAATCCGCAAGTGATC GAAACCTACCTGGGGCTCGCAAGAAAGGCGGTCTAG
Upstream 100 bases:
>100_bases TCGTGATGGAGTTCGGTACGCGGATCGCCGAAGGCTTGCCACAGGATGTGCAGAAGGATCCGGCAGTGCTGGAAGCCTAT CTCGGTGGGGTGGAGTGATG
Downstream 100 bases:
>100_bases CAGGGGCTCCGCTGGTTCCGGTCGACGGCGTGTTTCACGTGAAACACGCCGTTTTTTATGGTCGGCCGTTCGAACAAGAT TCGGGCCAAAACCGAACCCG
Product: putative branched-chain amino acid ABC transporter ATP-binding subunit
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHAAGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETSEIALEGPAGELAQNPQVI ETYLGLARKAV
Sequences:
>Translated_251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHAAGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETSEIALEGPAGELAQNPQVI ETYLGLARKAV >Mature_251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHAAGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETSEIALEGPAGELAQNPQVI ETYLGLARKAV
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27262624, Length=178, Percent_Identity=30.3370786516854, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI27262626, Length=178, Percent_Identity=30.3370786516854, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI45446740, Length=190, Percent_Identity=30, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI47078218, Length=190, Percent_Identity=30, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI105990541, Length=172, Percent_Identity=32.5581395348837, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI27881501, Length=183, Percent_Identity=28.4153005464481, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI30795238, Length=183, Percent_Identity=28.4153005464481, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI27477115, Length=194, Percent_Identity=32.4742268041237, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI153792144, Length=184, Percent_Identity=33.1521739130435, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI27436953, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI21536376, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI148612844, Length=223, Percent_Identity=29.5964125560538, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI31657092, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI255708477, Length=223, Percent_Identity=29.5964125560538, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI46592898, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI46592964, Length=208, Percent_Identity=25, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI46592956, Length=207, Percent_Identity=25.1207729468599, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI46592915, Length=207, Percent_Identity=25.1207729468599, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI46592971, Length=207, Percent_Identity=25.1207729468599, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI46592978, Length=207, Percent_Identity=25.1207729468599, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI87082268, Length=240, Percent_Identity=44.1666666666667, Blast_Score=204, Evalue=4e-54, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=31.9066147859922, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI1789593, Length=237, Percent_Identity=31.6455696202532, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI1787792, Length=257, Percent_Identity=29.1828793774319, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1790162, Length=242, Percent_Identity=28.5123966942149, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1789672, Length=241, Percent_Identity=27.3858921161826, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788053, Length=173, Percent_Identity=35.8381502890173, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1790190, Length=213, Percent_Identity=30.9859154929577, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=25.8333333333333, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI48994943, Length=242, Percent_Identity=30.5785123966942, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI87081709, Length=254, Percent_Identity=27.1653543307087, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI87081782, Length=232, Percent_Identity=30.1724137931034, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788472, Length=230, Percent_Identity=29.1304347826087, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=26.2931034482759, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1789991, Length=216, Percent_Identity=26.8518518518519, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=24.8927038626609, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787370, Length=227, Percent_Identity=26.431718061674, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=28.6343612334802, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789586, Length=248, Percent_Identity=28.2258064516129, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786698, Length=209, Percent_Identity=32.0574162679426, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1790525, Length=247, Percent_Identity=25.5060728744939, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788897, Length=232, Percent_Identity=28.448275862069, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787105, Length=246, Percent_Identity=27.6422764227642, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI1786563, Length=206, Percent_Identity=29.6116504854369, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=27.7056277056277, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=30.622009569378, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87081834, Length=219, Percent_Identity=27.8538812785388, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1790467, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786872, Length=238, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI48995001, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787712, Length=222, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1787759, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786319, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87082267, Length=163, Percent_Identity=31.9018404907975, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1788450, Length=227, Percent_Identity=25.9911894273128, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1790544, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1788165, Length=244, Percent_Identity=26.6393442622951, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI48994883, Length=229, Percent_Identity=25.3275109170306, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1790739, Length=247, Percent_Identity=25.1012145748988, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789032, Length=227, Percent_Identity=30.3964757709251, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787164, Length=221, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1788644, Length=247, Percent_Identity=27.1255060728745, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI71983516, Length=203, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71983510, Length=203, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71983523, Length=203, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17510237, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17565586, Length=177, Percent_Identity=31.638418079096, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193208177, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI115532730, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI115533608, Length=169, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322640, Length=226, Percent_Identity=27.4336283185841, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI221512771, Length=177, Percent_Identity=30.5084745762712, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI24666092, Length=180, Percent_Identity=31.1111111111111, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI28574533, Length=245, Percent_Identity=26.9387755102041, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI28574150, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007328, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24643674, Length=181, Percent_Identity=26.5193370165746, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI19920532, Length=215, Percent_Identity=26.9767441860465, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580930, Length=215, Percent_Identity=26.9767441860465, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28573573, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28573571, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24650853, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24650855, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI281362751, Length=225, Percent_Identity=27.5555555555556, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571209, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26726; Mature: 26726
Theoretical pI: Translated: 6.81; Mature: 6.81
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPT CCCCCCCEEEEECCEEEHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHCCC NGHAAGTVLYRGDDVDALPVEQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDA CCCCEEEEEECCCCCCCCCHHHHHHHCEEECCCHHHHEEECCCCCCEEEHHHHHHHCCCH SFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETSEIALEGPAGELAQNPQVI HHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEEECCCEEEECCCHHHHCCCHHH ETYLGLARKAV HHHHHHHHHCC >Mature Secondary Structure MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPT CCCCCCCEEEEECCEEEHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHCCC NGHAAGTVLYRGDDVDALPVEQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDA CCCCEEEEEECCCCCCCCCHHHHHHHCEEECCCHHHHEEECCCCCCEEEHHHHHHHCCCH SFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETSEIALEGPAGELAQNPQVI HHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEEECCCEEEECCCHHHHCCCHHH ETYLGLARKAV HHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]