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The map label for this gene is pilQ [H]

Identifier: 53720777

GI number: 53720777

Start: 3774618

End: 3775946

Strand: Reverse

Name: pilQ [H]

Synonym: BPSL3170

Alternate gene names: 53720777

Gene position: 3775946-3774618 (Counterclockwise)

Preceding gene: 53720778

Following gene: 53720776

Centisome position: 92.67

GC content: 69.98

Gene sequence:

>1329_bases
GTGCCGCTCGCGCCGGCGCAACGCATGAGCGACGAGCATCGTTCGTCGCCGCCGGCCGCCGGCGCCGTATCGACCGCGAG
CGTCGCCGGCACCGGCACCGAGACGGGCGATCCATCCGGCGACAATCGCCCGATCTCCATCAATCTGCAACAGGCGAGCC
TCGCCGCGGTCTTCGATGCATTCGCGCGTTTCACGGGCCTCAATATCGTGGTCAGCGAGCGGGTGCGCGGCACGGTGTCG
TTGCGTCTGAACAATGTCCGCTGGCGCAGTGCGTTCGATGCGCTGCTGGACGCCCACGGCCTCGCGATGGCGCGGCGCGG
CAGCGTGATATGGGTGGCGCCCGTCGCGGAACTCGCCGAGCGCGAGCGCCAGCGTTTCGATGCGCATGCGCGCGCCGCCC
AGCTCGAGCCGCTCGCGAGCCGCGGCTTCGTGCTGCGCTACGCGCGCGCGGCCGACGTGCAGCGTCTGCTCGCAGGCTCG
GCCGGCCAGCGCATCCTGTCCAAGCGCGGCTCGGTGTTGGCCGATCCTCGGACGAATCTGCTGTTCGTCACCGATCTGTC
CGGACGCCTCGCGCAGATCGCCGATCTGATCGGCAAGCTCGATACGCCGTCGCGCCAGGTATTGATCGAAGCGAGGATCG
TCGAGGGCGATCGCGGGTTCTCGCGCAATCTCGGCGCGCGCCTCGCGCTGCGCGCGCCCGATGCGGGCGAACGCGCGACG
GGCATCGTCGCCGGCCGCAACGGCACGCTGGCGGAGCTCGCCGCCAGGCCGATCAGCGGCTTCGACGCGGCGACGGCCGG
CCTCACGCTGTTCGCCGCGCGCGCGAGCCGCCTGCTCGACGTCGAGTTGAGCGCGCTCGAGGCCGAGGGCCGGGGCCAGA
TCGTGTCGAGCCCGCGCGTCGTGACGGCGGACCGGACCAAGGCCGTCGTCGAGCAGGGCGCCGAACTGCCGTACCAGGCG
AAGGTCGGCAACGGCGTATCCGGCGTCCAGTTCCGGCGCGCGACCTTGAAGCTCGAGGTCGAGCCGCAGATCACGCCCGA
CGGGCGTGTGATTCTCGATCTCGACGTCGCGAAGGATAGCGTCGGCGAGGAAACCGCGTCCGGCCCCGCGATTCATACGA
AGCATGTGCAGACGCGAGTGGAAGTCGAAAACGGCGGAACGGTGTCGATCGGCGGGATTTTCGAGAGCGACGACCGCGAC
GATGTGACTCGCGTGCCGCTCTTGGGCAAAATACCGGTGTTGGGCGCGCTTTTCAGGCATCGCGCGCAGCGTGCGCAGCG
CAGCGAGCTCGTCGTCTACATCACGCCGACCGTCGTGATCGGGCCCTGA

Upstream 100 bases:

>100_bases
GGCGGAACCGGCCCGCTCGACGTCCGCCGACGCCGGAACGTCGAGCGCAGTGGCATCGGCGGGGTTGCAAGCGCAGGAGG
CCGCGCTGGAGGGGCCGCCC

Downstream 100 bases:

>100_bases
CGCCCGTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACTCACTGAAGCAGAGGAAGCCG
TTGCAAGCGCGGGACCCACA

Product: putative secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPLAPAQRMSDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDAFARFTGLNIVVSERVRGTVS
LRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLLAGS
AGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERAT
GIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRVVTADRTKAVVEQGAELPYQA
KVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRD
DVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Sequences:

>Translated_442_residues
MPLAPAQRMSDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDAFARFTGLNIVVSERVRGTVS
LRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLLAGS
AGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERAT
GIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRVVTADRTKAVVEQGAELPYQA
KVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRD
DVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
>Mature_441_residues
PLAPAQRMSDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDAFARFTGLNIVVSERVRGTVSL
RLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLLAGSA
GQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERATG
IVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRVVTADRTKAVVEQGAELPYQAK
VGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDD
VTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=403, Percent_Identity=33.9950372208437, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=27.4869109947644, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 46958; Mature: 46827

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLAPAQRMSDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDA
CCCCCHHHHCHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
FARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAE
HHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHH
RERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNL
HHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCE
LFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERAT
EEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCE
GIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRV
EEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEECCCEE
VTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDS
EECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCC
VGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRH
CCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECCCCCCCHHHHHHHHH
RAQRAQRSELVVYITPTVVIGP
HHHHHHHCCEEEEEECEEEECC
>Mature Secondary Structure 
PLAPAQRMSDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDA
CCCCHHHHCHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
FARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAE
HHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHH
RERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNL
HHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCE
LFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERAT
EEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCE
GIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRV
EEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEECCCEE
VTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDS
EECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCC
VGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRH
CCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECCCCCCCHHHHHHHHH
RAQRAQRSELVVYITPTVVIGP
HHHHHHHCCEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]