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The map label for this gene is aroK

Identifier: 53720776

GI number: 53720776

Start: 3773983

End: 3774537

Strand: Reverse

Name: aroK

Synonym: BPSL3169

Alternate gene names: 53720776

Gene position: 3774537-3773983 (Counterclockwise)

Preceding gene: 53720777

Following gene: 53720775

Centisome position: 92.64

GC content: 65.41

Gene sequence:

>555_bases
TTGCAAGCGCGGGACCCACACGTGAACGTAATTTTCGTCGGGCTCATGGGGGCGGGTAAGACCACCGTGGGCCGGGCGGT
CGCGCGCCGGCTCGACAGACCCTTCTTCGATTCGGATCACGAGATCGAGGCGCGCACCGGCGCGCGCATTCCGGTCATCT
TCGAACTCGAGGGCGAAGCGGGCTTCCGTGACCGCGAGGCGCAGATGATCGCCGAGCTCACGCAGCGCGAGAACATCGTG
CTGGCGACGGGCGGCGGCGCGATCCTGCGCCCCGAGAACCGCAAGCTGCTTCACGAACGGGGCCTCGTCGTCTATCTGCG
CGCGAATCCGCACGATCTCTGGCTGCGCACCCGCAAGGACAAGAATCGCCCGCTGTTGCAGACCGACGATCCGAAAGCCA
AGCTCGAAGCGCTGTACGAAGCGCGCGATCCGCTCTACCGCGAATGCGCGCACTTCGTCATCGAAACCGGGCGGCCGTCC
GTCAACGGGCTCGTCAACATGGTGCTGATGCAGCTCGAAATGGCGGGCATCGTCGCCAAGCCACTCCAAGCATGA

Upstream 100 bases:

>100_bases
CCGTCGTGATCGGGCCCTGACGCCCGTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACT
CACTGAAGCAGAGGAAGCCG

Downstream 100 bases:

>100_bases
TTACCGTCAACGTCGACCTGGGCGAGCGCGCCTATCCGATCCACATCGGCGCCGATCTGATCGGCCGCACCGAGCTGTTC
GCGCCGCACATCGCGGGCGC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFRDREAQMIAELTQRENIV
LATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPS
VNGLVNMVLMQLEMAGIVAKPLQA

Sequences:

>Translated_184_residues
MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFRDREAQMIAELTQRENIV
LATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPS
VNGLVNMVLMQLEMAGIVAKPLQA
>Mature_184_residues
MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFRDREAQMIAELTQRENIV
LATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPS
VNGLVNMVLMQLEMAGIVAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=48.7951807228916, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=38.0645161290323, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_BURMA (Q62GA9)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_104265.1
- ProteinModelPortal:   Q62GA9
- SMR:   Q62GA9
- GeneID:   3091211
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA2747
- TIGR:   BMA2747
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- PhylomeDB:   Q62GA9
- ProtClustDB:   PRK00131
- BioCyc:   BMAL243160:BMA_2747-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20715; Mature: 20715

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS01128 SHIKIMATE_KINASE; PS00267 TACHYKININ

Important sites: BINDING 39-39 BINDING 63-63 BINDING 85-85 BINDING 123-123 BINDING 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGEA
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEECCCC
GFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKD
CCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCHHHHHHCCEEEEEECCCCEEEEEECCC
KNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
PLQA
CCCC
>Mature Secondary Structure
MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGEA
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEECCCC
GFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKD
CCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCHHHHHHCCEEEEEECCCCEEEEEECCC
KNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
PLQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA