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The map label for this gene is cysNC [H]

Identifier: 53719842

GI number: 53719842

Start: 2687392

End: 2688891

Strand: Reverse

Name: cysNC [H]

Synonym: BPSL2233

Alternate gene names: 53719842

Gene position: 2688891-2687392 (Counterclockwise)

Preceding gene: 53719846

Following gene: 53719841

Centisome position: 65.99

GC content: 72.67

Gene sequence:

>1500_bases
ATGAGAGAGCGTAGACGGGGTATTGCCTTTATGCGGTCCTGCGATGACTTTCTACGGACATCGGAATTGTCCATCGCGGC
GGTCAACAGCCTGCGGCGCACCATCGCGCCGTCGCATCGGGTGCTGGACGCGTGCGGATCGGGCGCCGCCTGCCTGCTGG
CGTCGCGCTACGGCGCGAAGCAGGTGGTGGCGCTCGCGGCCGCAGAGGCGACGCTCGTGGGGGCGCGAGCCGGCGCGAAC
GGTCCCGGCGAACGGATATCGTTCGTCGACGCCGAGCAGGCCGCGGCGCTCGTCGCGCGGCAAGGGCGGTTCGACGTCGT
GCTCGGGCTCGCAGGCGGCGGGCGCGACGGGCTCGATCCGCATTACGGCGCTCGGCTCGACGCGTTCGCACGGCGCTTCG
GCACGGCGAACGTTGCCGTCGTGCCCAACGGTGTGCGCTACGACGCGCAACTCGTCGAATGGCGCGAGGCCGAGCGGCTC
GAGGCGGACGTCGCGGCCAGGCAGCGCGCCCTCGAAGCGCGCTACGACCTCACGCTTGGCCCGGTGCTCGACCAGGTGGC
CGCCGGGGCCGCGCCGCGTGGCCGCGTGCGCGCCGACGCGCTGCGCGCGCTCTGCGCGCGGCTGCCGTTTCTGTCGTGCC
GGCCGGGCGATGGCGGTGATGCCGGTACAAGCGGCACAAGCGGCACGGCGGCGCCCGAGCATGTCGAGTTGACCGCCGCG
CACGGCGGCCGTGCCGACGGCGTGCTGTGGACGCAGGAGCTGATACACGACGGCATCGTCATCGAACGGATTCAGGGGTG
CAGCTGGCTCGACGAACGCGTCGATCTCGAGGCGGGCGACGCGATCGCGGTGCCCGTCGCCGACATGGCGCGGGCCGGGC
CGCTCGACGGCGGCGAAGCGCCGCCGCAGCTCGCGCCCGCGCCGCGCGCATCCGGCGCGCCCGCGCCGCTCGTCTTCTGG
CTGACCGGTATCTCGGGGGCCGGCAAGACGACGATCGCGACACGTTTCAAGCAGCGGGCGGACGCCGACGCGTGGCCCAC
CGTCGTGCTCGACGGCGACACGCTGCGCGGCGGCCTCAACGCGGATCTCGGCTTCTGCGACGCGGACCGCGCGGAGAACG
TGCGCCGCATCGCCGAGGTCGCGGCGCTGATGGCCGACACGGGGCTCGTCGTCGTCGTCTCGTGCATTTCGCCCAGGCGG
TCGTTTCGCGAAACGGCGCGCGAAATCGTCGGCGCCGAGCGCTTCGTCGAGGTGTTCGTCGATACGCCGCCCGCGGTCGC
GCAGGCGCGCGATCCGAAAGGGCTGTATCGGCGCGCACGCGCGGGGTTGATCGCGTCGTTCACCGGCATCGATTCGGACT
ACGAGCCACCGCCGGATCCGCAATTGCGCATCGATACGACGACGCACGACGTCGAGGACGCGACGCAGATGCTGCGCCGC
TACTACGTCGACGCGCGCCTGTCCGGCGCGCGTGCGGGCACCGCCGAGTGCGCGGCGTGA

Upstream 100 bases:

>100_bases
CGGTTGCCTTTCCGTAGCGCCGCAGAAGATCAAATACGACATTCCGAGGGCGCGTGCCTGTATTGCACGCGCATGTCAAA
ACGATTAAATGACGACGTCC

Downstream 100 bases:

>100_bases
CGCCGCCGCTCCGTTCCTTCCTTCGCCGACGGCCAATAGCGAGACAAACGATGAGCGTTCACGACATGACTCACCCGGGC
GAGCTCGCACCGGTGCGAGC

Product: putative adenylylsulfate kinase

Products: NA

Alternate protein names: Sulfate adenylyltransferase subunit 1; ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MRERRRGIAFMRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGAN
GPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERL
EADVAARQRALEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAA
HGGRADGVLWTQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAGPLDGGEAPPQLAPAPRASGAPAPLVFW
LTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRR
SFRETAREIVGAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRR
YYVDARLSGARAGTAECAA

Sequences:

>Translated_499_residues
MRERRRGIAFMRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGAN
GPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERL
EADVAARQRALEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAA
HGGRADGVLWTQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAGPLDGGEAPPQLAPAPRASGAPAPLVFW
LTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRR
SFRETAREIVGAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRR
YYVDARLSGARAGTAECAA
>Mature_499_residues
MRERRRGIAFMRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGAN
GPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERL
EADVAARQRALEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAA
HGGRADGVLWTQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAGPLDGGEAPPQLAPAPRASGAPAPLVFW
LTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRR
SFRETAREIVGAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRR
YYVDARLSGARAGTAECAA

Specific function: APS kinase catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=161, Percent_Identity=53.416149068323, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI34447231, Length=161, Percent_Identity=51.5527950310559, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI62912492, Length=161, Percent_Identity=51.5527950310559, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1789107, Length=167, Percent_Identity=49.7005988023952, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17542422, Length=161, Percent_Identity=45.9627329192547, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322852, Length=172, Percent_Identity=44.1860465116279, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24667032, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667028, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667036, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667040, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007838, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24667044, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR000795
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF01583 APS_kinase; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 52678; Mature: 52678

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERRRGIAFMRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAK
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHH
QVVALAAAEATLVGARAGANGPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDP
HHHHHHHHHHHEEECCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
HYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRALEARYDLTLG
CCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
PVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAA
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
HGGRADGVLWTQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAGPLDGGEA
CCCCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCC
PPQLAPAPRASGAPAPLVFWLTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLN
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
ADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIVGAERFVEVFV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHC
DTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRR
CCCCHHHCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
YYVDARLSGARAGTAECAA
HHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MRERRRGIAFMRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAK
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHH
QVVALAAAEATLVGARAGANGPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDP
HHHHHHHHHHHEEECCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
HYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRALEARYDLTLG
CCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
PVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAA
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
HGGRADGVLWTQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAGPLDGGEA
CCCCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCC
PPQLAPAPRASGAPAPLVFWLTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLN
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
ADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIVGAERFVEVFV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHC
DTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRR
CCCCHHHCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
YYVDARLSGARAGTAECAA
HHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]