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The map label for this gene is fabZ [H]

Identifier: 53719757

GI number: 53719757

Start: 2577935

End: 2578444

Strand: Reverse

Name: fabZ [H]

Synonym: BPSL2148

Alternate gene names: 53719757

Gene position: 2578444-2577935 (Counterclockwise)

Preceding gene: 53719758

Following gene: 53719756

Centisome position: 63.28

GC content: 61.57

Gene sequence:

>510_bases
TTGCAGTCATCACCGCGCAGCCATTGCGTGAGACGAACCATCATGAGCACTGAAAAAATCAACTTCGACATTCACAAGAT
CCTCACGCTGCTGCCGCACCGCTATCCGATTCTGCTCGTCGATCGCGTGCTCGAACTCGAACCGCACAAGGCCATCAAGG
CGCTGAAGAACGTGACGGTCAACGAGCCGTTCTTCACCGGCCACTTTCCGAAGCGGCCGGTGATGCCGGGCGTGCTGATC
ATCGAGGCGCTCGCGCAGGCGGCCGCGCTCCTCACGTTCGCCGAGGCGCAGCCGAAGGATCCGGAGAACACGCTGTATTA
CTTCGTCGGCATCGACAACGCGCGCTTCAAGCGCGTCGTCGAGCCGGGCGACCAGTTGATCCTGAACGTGACGTTCGAGC
GCTATATTCGCGGCATCTGGAAGTTCAAGGCCGTTGCGGAAGTGGACGGCAAGGTCGCGGCGGAAGCCGAGCTGATGTGC
ACGGTCAAGACGGCCGACGCGGCGCCCTGA

Upstream 100 bases:

>100_bases
CACGTCGGCCGCAACCGCGCGCCGCAGCACTCGCAGGCTGCCCGCCGCACCGGCCGATCGAACCGCGCGCCGCTTTCCCC
GACGCGGCCCGCATCAGCAT

Downstream 100 bases:

>100_bases
GCGCGCGGCACGCAAGGCTACGCAACGCGACATAGACATTGAGAGGCAACGGCGCATGAGCAGGATTCACCCCACGGCGA
TCATCGAGCCGGGCGCGCAG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQSSPRSHCVRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLI
IEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMC
TVKTADAAP

Sequences:

>Translated_169_residues
MQSSPRSHCVRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLI
IEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMC
TVKTADAAP
>Mature_169_residues
MQSSPRSHCVRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLI
IEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMC
TVKTADAAP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=57.5342465753425, Blast_Score=177, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 19053; Mature: 19053

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSPRSHCVRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTV
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NEPFFTGHFPKRPVMPGVLIIEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVV
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHC
EPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
CCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC
>Mature Secondary Structure
MQSSPRSHCVRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTV
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NEPFFTGHFPKRPVMPGVLIIEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVV
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHC
EPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
CCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA